Molecular Nutrition

Effects of Bacillus subtilis CGMCC 1.921 on Performance, Routine Blood Parameters, Serum Biochemical Parameters and Immunoglobulin Contents of Laying Hens

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  • Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China

Received date: 2016-08-28

  Online published: 2017-02-17

Abstract

This study was conducted to investigate the effects of Bacillus subtilis CGMCC 1.921 on performance, routine blood parameters, serum biochemical parameters and immunoglobulin contents of laying hens. A total of 360 twenty-seven-week-old healthy Hy-Line brown laying hens were randomly allocated into 5 groups with 6 replicates per group and 12 birds per replicate. The control group (group 1) was fed a basal diet, and the experimental groups (groups 2 to 5) were fed the basal diets supplemented with 1.0×105, 1.0×106, 1.0×107 and 1.0×108 CFU/g Bacillus subtilis CGMCC 1.921, respectively. The experiment lasted for 24 weeks. The results showed that there were no significant differences in egg production, feed intake, egg weight, egg weight per hen and mortality among all groups (P>0.05). However, group 2, 4, 5 significantly decreased feed to egg ratio compared with the control group (P<0.05). Dietary Bacillus subtilis CGMCC 1.921 supplementation significantly increased serum glucose content (weeks 2, 3, 12, 16 and 20) (P<0.05), and significantly decreased serum urea content (weeks 2, 3, 8 and 12) (P<0.05). Dietary Bacillus subtilis CGMCC 1.921 supplementation significantly increased blood leucocytes (weeks 1, 3, 4, 8, 12, 16, 20 and 24) and lymphocytes counts (weeks 2, 3, 4, 8, 12, 16, 20 and 24) (P<0.05), and significantly increased serum immunoglobulin G (weeks 1 and 4) and immunoglobulin M contents (weeks 2, 4, 8 and 16) (P<0.05). Therefore, dietary Bacillus subtilis CGMCC 1.921 supplementation can decrease the feed to egg ratio, improve serum glucose and urea contents and routine blood test parameters, and enhance immunity of laying hens to a certain extent.

Cite this article

GUO Junrui, DONG Xiaofang, TONG Jianming . Effects of Bacillus subtilis CGMCC 1.921 on Performance, Routine Blood Parameters, Serum Biochemical Parameters and Immunoglobulin Contents of Laying Hens[J]. Chinese Journal of Animal Nutrition, 2017 , 29(2) : 465 -478 . DOI: 10.3969/j.issn.1006-267x.2017.02.014

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