Effects of Illicium verum and Eucommia Leaf Extracts on Growth Performance, Serum Enzyme Activities and Distribution and Expression of Tumor Necrosis Factor &alpha; in Liver of Weaned Piglets

CHEN Peng, YANG Zaibin, HUANG Libo, DING Xiao, JIANG Shuzhen

doi:10.3969/j.issn.1006-267x.2017.03.018

2017 , Vol. 29 >Issue 3: 874 - 881

DOI: https://doi.org/10.3969/j.issn.1006-267x.2017.03.018

Molecular Nutrition

Effects of Illicium verum and Eucommia Leaf Extracts on Growth Performance, Serum Enzyme Activities and Distribution and Expression of Tumor Necrosis Factor α in Liver of Weaned Piglets

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College of Animal Science and Technology, Shandong Agricultural University, Tai'an 271018, China

Received date: 2016-09-02

Online published: 2017-03-09

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Abstract

The aims of this study were to investigate the effects of Illicium verum and Eucommia leaf extracts on growth performance, serum enzyme activities and distribution and expression of tumor necrosis factor α (TNF-α) in liver of weaned piglets. The single factorial experimental design was adopted in this experiment. Forty-eight healthy weaned piglets (Duroc×Large White×Landrace) were randomly allocated into 4 groups with 3 replicates per group and 4 piglets per replicate. Piglets in the control group were fed a basal diet, and the others were fed basal diets supplemented with Illicium verum extract (500 mg/kg), Eucommia leaf extract (250 mg/kg) and aureomycin (50 mg/kg), respectively. The trial lasted for 42 days after 7 days adaptation. The results showed that compared with the control group, dietary supplemented with Illicium verum extract, Eucommia leaf extract and aureomycin significantly increased the average daily gain of weaned piglets (P<0.05), dietary supplemented with Illicium verum and Eucommia leaf extracts significantly reduced the activities of glutamic-pyruvic transaminase and alkaline phosphatase in serum and the mRNA relative expression level of TNF-α in liver of weaned piglets (P<0.05). There was a higher intensity of immunopositive staining of TNF-α in blood sinus and among hepatic lobule of liver. The results suggested that dietary supplemented with Illicium verum and Eucommia leaf extracts can improve the growth performance of weaned piglets, and the ability of resist inflammation and oxidative stress of the liver is also observed.

Key words： Illicium verum extract; Eucommia leaf extract; weaned piglets; growth performance; serum enzyme

Cite this article

CHEN Peng, YANG Zaibin, HUANG Libo, DING Xiao, JIANG Shuzhen . Effects of Illicium verum and Eucommia Leaf Extracts on Growth Performance, Serum Enzyme Activities and Distribution and Expression of Tumor Necrosis Factor α in Liver of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2017 , 29(3) : 874 -881 . DOI: 10.3969/j.issn.1006-267x.2017.03.018

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