Molecular Nutrition

Research Progress in Relevant Candidate Genes of Animal Intramuscular Fat Deposition

Expand
  • State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China

Received date: 2016-11-01

  Online published: 2017-05-13

Abstract

Intramuscular fat (IMF) content is an important factor in the evaluation of meat quality,which plays important roles in flavor, tenderness and texture of meat sensory quality, however, the regulation of intramuscular fat deposition is mainly affected by three metabolic pathways, namely, fat uptake, synthesis and decomposition. This paper reviewed the related candidate genes of intramuscular fat deposition, preliminarily revealing the influence mechanism of fat metabolism, so as to provide a theoretical basis for further study of the regulation of intramuscular fat deposition.

Cite this article

WANG Yiping, XU Chenchen, LUO Hailing . Research Progress in Relevant Candidate Genes of Animal Intramuscular Fat Deposition[J]. Chinese Journal of Animal Nutrition, 2017 , 29(5) : 1475 -1480 . DOI: 10.3969/j.issn.1006-267x.2017.05.004

References

[1] HOCQUETTE J F,GONDRET F,BAÉZA E,et al.Intramuscular fat content in meat-producing animals:development,genetic and nutritional control,and identification of putative markers[J].Animal,2010,4(2):303-319.  

[2] GAO S Z,ZHAO S M.Physiology,affecting factors and strategies for control of pig meat intramuscular fat[J].Recent Patents on Food,Nutrition & Agriculture,2009,1(1):59-74.  

[3] WATKINS P J,FRANK D,SINGH T K,et al.Sheepmeat flavor and the effect of different feeding systems:a review[J].Journal of Agricultural and Food Chemistry,2013,61(15):3561-3579.  

[4] MATEESCU R G,GARRICK D J,GARMYN A J,et al.Genetic parameters for sensory traits in longissimus muscle and their associations with tenderness,marbling score,and intramuscular fat in Angus cattle[J].Journal of Animal Science,2015,93(1):21-27.  

[5] 罗嘉,蒲强,余霞,等.猪肌内脂肪沉积机理研究进展[J].猪业科学,2014(10):114-116.

[6] GAJDA A M,STORCH J.Enterocyte fatty acid-binding proteins (FABPs):different functions of liver and intestinal FABPs in the intestine[J].Prostaglandins,Leukotrienes and Essential Fatty Acids,2015,93:9-16.

[7] HE J,CHEN J C,LU L Z,et al.A novel SNP of liver-type fatty acid-binding protein gene in duck and its associations with the intramuscular fat[J].Molecular Biology Reports,2012,39(2):1073-1077.  

[8] KURIAN E,KIRK W R.Prendergast F G.Affinity of fatty acid for rRat intestinal fatty acid binding protein:further examination[J].Biochemistry,1996,35(12):3865-3874.  

[9] LEE S H,CHOI Y M,CHOE J H,et al.Association between polymorphisms of the heart fatty acid binding protein gene and intramuscular fat content,fatty acid composition,and meat quality in Berkshire breed[J].Meat Science,2010,86(3):794-800.  

[10] CHO K H,KIM M J,JEON G J,et al.Association of genetic variants for FABP3 gene with back fat thickness and intramuscular fat content in pig[J].Molecular Biology Reports,2011,38(3):2161-2166.  

[11] HOCQUETTE J F,CASSAR-MALEK I,JURIE C,et al.Relationships between muscle growth potential,intramuscular fat content and different indicators of muscle fibre types in young Charolais bulls[J].Animal Science Journal,2012,83(11):750-758.  

[12] GUO B,KONGSUWAN K,GREENWOOD P L,et al.A gene expression estimator of intramuscular fat percentage for use in both cattle and sheep[J].Journal of Animal Science and Biotechnology,2014,5:35.

[13] YANG Y,SONG J,FU R Q,et al.AMPK subunit expression regulates intramuscular fat content and muscle fiber type in chickens[J].Agricultural Science & Technology,2015,16(5):1006-1010.

[14] JEONG J,KWON E G,IM S K,et al.Expression of fat deposition and fat removal genes is associated with intramuscular fat content in longissimus dorsi muscle of Korean cattle steers[J].Journal of Animal Science,2012,90(6):2044-2053.  

[15] DALRYMPLE B P,GUO B,ZHOU G H,et al.Using muscle gene expression to estimate triacylglyceride deposition,and relative contributions of fatty acid synthesis and fatty acid import in intramuscular fat in cattle[J].Animal Production Science,2014,54(9):1436-1442.

[16] BONNET M,FAULCONNIER Y,LEROUX C,et al.Glucose-6-phosphate dehydrogenase and leptin are related to marbling differences among Limousin and Angus or Japanese Black×Angus steers[J].Journal of Animal Science,2007,85(11):2882-2894.  

[17] YANG Z Q,BAO L B,ZHAO X H,et al.Nicotinic acid supplementation in diet favored intramuscular fat deposition and lipid metabolism in finishing steers[J].Experimental Biology and Medicine,2016,241(11):1195-1201.  

[18] ZHAO X H,YANG Z Q,BAO L B,et al.Daidzein enhances intramuscular fat deposition and improves meat quality in finishing steers[J].Experimental Biology and Medicine,2015,240(9):1152-1157.  

[19] CHOI M S,JUNG U J,YEO J,et al.Genistein and daidzein prevent diabetes onset by elevating insulin level and altering hepatic gluconeogenic and lipogenic enzyme activities in non-obese diabetic (NOD) mice[J].Diabetes/Metabolism Research and Reviews,2008,24(1):74-81.  

[20] 李洁琼,郑世学,喻子牛,等.乙酰辅酶A羧化酶:脂肪酸代谢的关键酶及其基因克隆研究进展[J].应用与环境生物学报,2011,17(5):753-758.

[21] DE JAGER N,HUDSON N J,REVERTER A,et al.Gene expression phenotypes for lipid metabolism and intramuscular fat in skeletal muscle of cattle[J].Journal of Animal Science,2013,91(3):1112-1128.  

[22] WARD R E,WOODWARD B,OTTER N,et al.Relationship between the expression of key lipogenic enzymes,fatty acid composition,and intramuscular fat content of Limousin and Aberdeen Angus cattle[J].Livestock Science,2010,127(1):22-29.  

[23] CUI H X,ZHENG M Q,LIU R R,et al.Liver dominant expression of fatty acid synthase (FAS) gene in two chicken breeds during intramuscular-fat development[J].Molecular Biology Reports,2012,39(4):3479-3484.  

[24] ANTON I,KOVÁCS K,HOLLÓ G,et al.Effect of leptin,DGAT1 and TG gene polymorphisms on the intramuscular fat of Angus cattle in Hungary[J].Livestock Science,2011,135(2/3):300-303.

[25] WU X X,YANG Z P,SHI X K,et al.Association of SCD1 and DGAT1 SNPs with the intramuscular fat traits in Chinese Simmental cattle and their distribution in eight Chinese cattle breeds[J].Molecular Biology Reports,2012,39(2):1065-1071.  

[26] LI T,XU D Q,ZUO B,et al.Ectopic overexpression of porcine DGAT1 increases intramuscular fat content in mouse skeletal muscle[J].Transgenic Research,2013,22(1):187-194.  

[27] AVILÉS C,HORCADA A,POLVILLO O,et al.Association study between variability in the SCD gene and the fatty acid profile in perirenal and intramuscular fat deposits from Spanish goat populations[J].Small Ruminant Research,2016,136:127-131.

[28] RENAVILLE B,PRANDI A,FAN B,et al.Candidate gene marker associations with fatty acid profiles in heavy pigs[J].Meat Science,2013,93(3):495-500.  

[29] LI C,ALDAI N,VINSKY M,et al.Association analyses of single nucleotide polymorphisms in bovine stearoyl-CoA desaturase and fatty acid synthase genes with fatty acid composition in commercial cross-bred beef steers[J].Animal Genetics,2012,43(1):93-97.  

[30] 任善茂,赵旭庭,周春宝,等.猪HSL基因多态性与胴体性状及肌肉品质的相关性分析[J].湖南农业科学,2014(13):55-57.

[31] QIAO Y,HUANG Z G,LI Q F,et al.Developmental changes of the FAS and HSL mRNA expression and their effects on the content of intramuscular fat in Kazak and Xinjiang sheep[J].Journal of Genetics and Genomics,2007,34(10):909-917.  

[32] XU X C,WEI X,YANG Y X,et al.mRNA transcription and protein expression of PPARγ,FAS,and HSL in different parts of the carcass between fat-tailed and thin-tailed sheep[J].Electronic Journal of Biotechnology,2015,18(3):215-220.  

[33] 王刚,曾勇庆,武英,等.猪肌肉组织LPL基因表达的发育性变化及其与肌内脂肪沉积关系的研究[J].畜牧兽医学报,2007,38(3):253-257.

[34] WANG W,XUE W,ZHOU X,et al.Effects of candidate genes' polymorphisms on meat quality traits in pigs[J].Acta Agriculturae Scandinavica,Section A:Animal Science,2012,62(3):120-126.  

[35] ZHANG X D,LI Q H,LOU L F,et al.High-resolution melting curve analysis of the ADSL and LPL genes and their correlation with meat quality and blood parameters in chickens[J].Genetics and Molecular Research,2015,14(1):2031-2040.  
Outlines

/