Effects of Yeast Cell Wall Polysaccharide on Peripheral Blood and Gut Immunity of Weaned Piglets

HE Qin, WANG Zirui, YOU Jinming, LUO Bowen, LU Yafei, LI Lanhai

doi:10.3969/j.issn.1006-267x.2017.07.035

Chinese Journal of Animal Nutrition >

2017 , Vol. 29 >Issue 7: 2502 - 2511

DOI: https://doi.org/10.3969/j.issn.1006-267x.2017.07.035

Molecular Nutrition

Effects of Yeast Cell Wall Polysaccharide on Peripheral Blood and Gut Immunity of Weaned Piglets

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Nutrition Feed Development Engineering Center of Jiangxi Province, Key Laboratory of Animal Nutrition in Jiangxi Province, Jiangxi Agricultural University, Nanchang 330045, China

Received date: 2017-01-20

Online published: 2017-07-05

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Abstract

This experiment was conducted to determine the effects of yeast cell wall polysaccharide on peripheral blood and gut immunity of weaned piglets. The experiment was used a single factor experimental design method, a total of 180 piglets with the similar genetic background and health condition weaned at 21 days of age were randomly allotted to 4 groups with 5 replicates per group and 9 pigs per replicate. Pigs in the 4 groups were fed the experimental diets supplemented with 0 (control group), 0.15%, 0.30% and 0.45% yeast cell wall polysaccharide, respectively. The experiment lasted for 21 days. The results showed as follows: 1) compared with the control group, diets supplemented with 0.15%, 0.30% and 0.45% yeast cell wall polysaccharide significantly increased the serum immunoglobulin A content of weaned piglets (P<0.05), diets supplemented with 0.30% and 0.45% yeast cell wall polysaccharide significantly increased the serum immunoglobulin G content of weaned piglets (P<0.05). 2) Compared with the control group, diets supplemented with 0.15%, 0.30% and 0.45% yeast cell wall polysaccharide significantly decreased the serum interferon-γ content of weaned piglets (P<0.05), diets supplemented with 0.30% yeast cell wall polysaccharide significantly increased the serum interleukin-10 content of weaned piglets (P<0.05). Diets supplemented with yeast cell wall polysaccharide had no significant effects on the contents of interleukin-2, interleukin-6 and tumor necrosis factor-α in serum of weaned piglets (P>0.05). 3) Compared with the control group, diets supplemented with 0.30% and 0.45% yeast cell wall polysaccharide significantly increased the ileum CD4⁺ lymphocytes content of weaned piglets (P<0.05), diets supplemented with yeast cell wall polysaccharide could increased the ileum CD8⁺ and CD20⁺ lymphocytes contents of weaned piglets to a certain extent, but the difference was not significant (P>0.05). These findings indicate that yeast cell wall polysaccharide may enhance the peripheral blood and gut immunity in weaned piglets,relieve the weaning stress of the piglets.

Key words： yeast cell wall polysaccharide; weaned piglets; immunoglobulin; lymphocytes

Cite this article

HE Qin, WANG Zirui, YOU Jinming, LUO Bowen, LU Yafei, LI Lanhai . Effects of Yeast Cell Wall Polysaccharide on Peripheral Blood and Gut Immunity of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2017 , 29(7) : 2502 -2511 . DOI: 10.3969/j.issn.1006-267x.2017.07.035

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