Molecular Nutrition

Molecular Mechanisms of Ruminal Epithelial Cell Proliferation and Substance Transportation

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  • Key Laboratory of Feed Biotechnology of the Ministry of Agriculture, Feed Research Institute of Chinese Academy of Agricultural Sciences, Beijing 100081, China

Received date: 2017-01-12

  Online published: 2017-08-02

Abstract

The rumen is a critical organ mediating nutrient uptake and use in ruminants. A considerable research has been focused on the development of ruminal epithelium and substance transportation in nearly a half century. Many transporters and regulators associated with the ruminal epithelial cell proliferation and their metabolic pathway were explored, such as insulin-like growth factor and epidermal growth factor were associated with glucose transporters, and Na+/H+ exchanger protein, mono-carboxylate transporter family and G protein-coupled receptor were associated with short chain fatty acid transportation. However, hitherto the molecular mechanisms involved in the rumen development remain unclear. In this paper, the molecular mechanisms of ruminal epithelial cell proliferation and substance transportation were reviewed. It is important to further understand the process of rumen epithelium development and establish the best ruminant nutrition supply strategy.

Cite this article

LYU Xiaokang, WANG Jie, DIAO Qiyu, ZHANG Naifeng . Molecular Mechanisms of Ruminal Epithelial Cell Proliferation and Substance Transportation[J]. Chinese Journal of Animal Nutrition, 2017 , 29(8) : 2657 -2664 . DOI: 10.3969/j.issn.1006-267x.2017.08.007

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