Molecular Nutrition

Evaluation of Mycotoxin Toxicity Based on Cell Model in Vitro

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  • 1. Institute of Quality Standard & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences; Key Laboratory of Agro-Food Safety and Quality, Ministry of Agriculture, Beijing 100081, China;
    2. College of Animal Science and Technology, Beijing University of Agriculture, Beijing 102206, China

Received date: 2017-02-01

  Online published: 2017-08-02

Abstract

Mycotoxins are secondary metabolites produced by various fungi, which are widely found in food and feed. The contamination of mycotoxins on food and feed will result a large risk in livestock production and quality and safety of animal products. It is necessary to study the toxic mechanism of mycotoxins in order to evaluating the risk of food and feed safety. As a commonly used method in vitro, cell model is widely used in toxicology research. This paper reviews general property, toxicity and toxic mechanism of aflatoxin B1, ochratoxin A, deoxynivalenol, zearalenone and patulin based on cell model in vitro.

Key words: mycotoxin; toxicity; cell model

Cite this article

QIU Siqi, XU Zhenzhen, SHEN Hong, YANG Shuming, CHEN Ailiang, ZHAO Yan . Evaluation of Mycotoxin Toxicity Based on Cell Model in Vitro[J]. Chinese Journal of Animal Nutrition, 2017 , 29(8) : 2665 -2675 . DOI: 10.3969/j.issn.1006-267x.2017.08.008

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