Molecular Nutrition

Effects of Cysteamine Hydrochloride on Performance of Heat-Stressed Mid-Lactating Dairy Cows

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  • 1. College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China;
    2. State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Science, Beijing 100193, China;
    3. Beijing Dairy Cattle Center, Beijing 100192, China;
    4. Ministry of Agriculture-Milk and Dairy Product Inspection Center (Beijing), Beijing 100193, China;
    5. Jinrijiankang Dairy Co., Ltd., Tianjin Mengde Group, Tianjin 300400, China

Received date: 2017-02-01

  Online published: 2017-08-02

Abstract

This study aimed at researching the effects of cysteamine hydrochloride (CSH) on performance of mid-lactating cows suffered from heat stress in free stall barn. Forty-eight healthy mid-lactation Holstein dairy cows with body weight of (562.25±37.85) kg, milk yield of (26.58±1.58) kg, (1.23±0.42) parities and (123.64±10.67) d in milk were randomly divided into 4 groups (12 cows per group). Cows in 4 groups were fed diets containing 0 (control), 3, 15 and 30 g/kg CSH in diet, respectively. The pre-trial lasted for 12 d, and the trial lasted for 30 d. The results showed as follows: with the increase of CSH supplemental level, respiratory rate and rectal temperature was linearly significantly reduced (P<0.05); dry matter intake, 4% fat-corrected milk yield, energy-corrected milk yield, milk fat percentage and milk protein percentage were quadratically significantly change of firstly increased and then decreased (P<0.05), and 3 g/kg group showed better effects; at the end of trial period, compared with control group, serum thyroxin concentration in 3 and 15 g/kg groups was significantly decreased (P<0.05), and serum cortisol concentration in 15 g/kg group was significantly increased (P<0.05). The results indicate that CSH can effectively relief heat stress of mid-lactating cows in free stall barn, and increase milk yield and milk quality. The optimum CSH supplemental level in diet is 3 g/kg under the conditions in the present study.

Cite this article

LYU Zhongwang, LIU Hui, LIU Wei, BU Dengpan, SUN Peng, WANG Jiaqi, YU Xiong, YANG Kailun, WANG Zhiming, YU Qing . Effects of Cysteamine Hydrochloride on Performance of Heat-Stressed Mid-Lactating Dairy Cows[J]. Chinese Journal of Animal Nutrition, 2017 , 29(8) : 2777 -2784 . DOI: 10.3969/j.issn.1006-267x.2017.08.021

References

[1] XIAO D,LIN H R.Effect of cysteamine hydrochloride on growth hormone secretion from hypothalamus-pituitary tissue in juvenile grass carp (Ctenopharyngodon idellus)[J].Acta Zoologica Sinica,2002,49(5):600-605.

[2] HU Y,NI Y,REN L,et al.Leptin is involved in the effects of cysteamine on egg laying of hens,characteristics of eggs,and posthatch growth of broiler offspring[J].Poultry Science,2008,87(9):1810-1817.  

[3] DU G,SHI Z,XIA D,et al.Cysteamine improves growth performance and gastric ghrelin expression in preweaning piglets[J].Domestic Animal Endocrinology,2012,42(4):203-209.  

[4] LIU G M,WANG Z S,WU D,et al.Effects of dietary cysteamine supplementation on growth performance and whole-body protein turnover in finishing pigs[J].Livestock Science,2009,122(1):86-89.  

[5] LI Y,LIU X C,ZHANG Y,et al.Effects of cysteamine on mRNA levels of growth hormone and its receptors and growth in orange-spotted grouper (Epinephelus coioides)[J].Fish Physiology and Biochemistry,2013,39(3):605-613.  

[6] 叶继丹,王子甲,王琨.饲料中不同半胱胺添加水平对牙鲆生长性能及血液生化指标的影响[J].水产学杂志,2009,22(3):19-22.

[7] 张英杰,刘月琴,孙洪新.饲喂半胱胺对绵羊小肠主要消化酶活性的影响[J].畜牧兽医学报,2006,37(10):999-1002.

[8] 王月影,王艳玲,杨国宇,等.半胱胺促进奶山羊乳腺发育的试验研究[J].家畜生态学报,2006,26(6):9-12.

[9] 王艳玲,李振田,董秀钿,等.半胱胺对奶牛产奶量及血浆生长抑素、生长激素水平的影响[J].中国畜牧杂志,1999,35(6):14-15.

[10] 沈赞明,张荣飞,解红梅,等.半胱胺盐酸盐对泌乳20-42周奶牛产奶性能和部分免疫指标的影响[J].畜牧兽医学报,2005,36(7):667-673.

[11] CHOPRA V S,CHALIFOUR L E,SCHIPPER H M.Differential effects of cysteamine on heat shock protein induction and cytoplasmic granulation in astrocytes and glioma cells[J].Molecular Brain Research,1995,31(1/2):173-184.  

[12] SAKATANI M,BALBOULA A Z,YAMANAKA K,et al.Effect of heat shock and cysteamine during in vitro fertilization on preimplantation development of bovine embryo[C]//Biology of Reproduction.Madison:SOC Study Reproduction,2010:107-108.

[13] 沈赞明,张荣飞.半胱胺盐酸盐对高温条件下泌乳后期奶牛生产性能的影响[J].中国应用生理学杂志,2005,20(4):402-405.

[14] 高俊梅,陈军,丁威,等.CT2000对高温季节奶牛产奶性能的影响[J].家畜生态学报,2008,29(2):30-34.

[15] 张荣飞,沈赞明.半胱胺盐酸盐对高温季节奶牛生产性能的影响[J].动物营养学报,2007,19(2):153-156.

[16] PAN L,BU D P,WANG J Q,et al.Effects of Radix bupleuri extract supplementation on lactation performance and rumen fermentation in heat-stressed lactating Holstein cows[J].Animal Feed Science and Technology,2014,187:1-8.  

[17] HAISAN J,SUN Y,GUAN L L,et al.The effects of feeding 3-nitrooxypropanol on methane emissions and productivity of Holstein cows in mid lactation[J].Journal of Dairy Science,2014,97(5):3110-3119.  

[18] BU D P,WANG J Q,DHIMAN T R,et al.Effectiveness of oils rich in linoleic and linolenic acids to enhance conjugated linoleic acid in milk from dairy cows[J].Journal of Dairy Science,2007,90(2):998-1007.  

[19] WEST J W.Effects of heat-stress on production in dairy cattle[J].Journal of Dairy Science,2003,86(6):2131-2144.  

[20] RAVAGNOLO O,MISZTAL I.Genetic component of heat stress in dairy cattle,parameter estimation[J].Journal of Dairy Science,2000,83(9):2126-2130.  

[21] MACKLE T R,DWYER D A,INGVARTSEN K L,et al.Effects of insulin and amino acids on milk protein concentration and yield from dairy cows[J].Journal of Dairy Science,1999,82(7):1512-1524.  

[22] MACKLE T R,DWYER D A,INGVARTSEN K L,et al.Effects of insulin and postruminal supply of protein on use of amino acids by the mammary gland for milk protein synthesis[J].Journal of Dairy Science,2000,83(1):93-105.  

[23] SZABO S,REICHLIN S.Somatostatin in rat tissues is depleted by cysteamine administration[J].Endocrinology,1981,109(6):2255-2257.  

[24] MCLEOD K R,HARMON D L,SCHILLO K K,et al.Effects of cysteamine on pulsatile growth hormone release and plasma insulin concentrations in sheep[J].Comparative Biochemistry and Physiology Part B:Biochemistry and Molecular Biology,1995,112(3):523-533.  

[25] UMPHREY J E,MOSS B R,WILCOX C J,et al.Interrelationships in lactating Holsteins of rectal and skin temperatures,milk yield and composition,dry matter intake,body weight,and feed efficiency in summer in Alabama[J].Journal of Dairy Science,2001,84(12):2680-2685.  

[26] 李建国,桑润滋,张正珊,等.热应激对奶牛生理常值、血液生化指标、繁殖及泌乳性能的影响[J].河北农业大学学报,1998,21(4):69-75.

[27] 宋代军,何钦,姚焰础.热应激对不同泌乳阶段奶牛生产性能和血清激素浓度的影响[J].动物营养学报,2013,25(10):2294-2302.

[28] AL-SAIADY M Y,AL-SHAIKH M A,AL-MUFARREJ S I,et al.Effect of chelated chromium supplementation on lactation performance and blood parameters of Holstein cows under heat stress[J].Animal feed science and technology,2004,117(3/4):223-233.
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