Molecular Nutrition

Effects of Glucose Oxidase on Growth Performance, Serum Biochemical Indexes and Antioxidant Function, and Nutrient Digestibility of Weaned Piglets

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  • 1. Institute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, China;
    2. Hunan Institute of Animal Science and Veterinary Medicine, Changsha 410131, China;
    3. Jinan Nornoon Biological Engineering Co., Ltd., Ji'nan 250003, China

Received date: 2017-03-30

  Online published: 2017-09-28

Abstract

This experiment was designed to study the effects of dietary supplementation of glucose oxidase (GOD) on growth performance, serum biochemical indexes, serum antioxidant function and nutrient digestibility of weaned piglets. A total of one hundred and fifty 28-day-old weaned piglets[average body weight was (8.41±0.06) kg] were randomly assigned to five groups with 3 replicates per group and 10 piglets (half male and half female) per replicate. Piglets in control group were fed a basal diet and those in test groups Ⅰ to Ⅳ were fed the basal diet supplemented with 120, 180, 240 and 300 U/kg GOD, respectively. The experiment lasted for 30 d. The results as follows:1) compared with control group, final weight, average daily gain (ADG), average daily feed intake (ADFI) and feed to gain ratio (F/G) of piglets were not significantly changed by GOD supplementation (P>0.05). Diarrhea rate of piglets in test group Ⅱ was significantly decreased (P<0.05). 2) Serum albumin (ALB) content of piglets in test group Ⅳ was significantly higher than that in control group (P<0.05). Serum urea nitrogen (UN) content of piglets in test groups Ⅲ and Ⅳ was significantly higher than that in control group (P<0.05). 3) Serum superoxide dismutase (SOD) activity of piglets in test group Ⅱ was significantly higher than that in test groups Ⅲ and Ⅳ (P<0.05). Serum malondialdehyde (MDA) content in test groups Ⅱ and Ⅲ was significantly lower than that in control group and test group Ⅳ (P<0.05). 4) Dry matter digestibility of piglets in test group Ⅱ was significant higher than that in control group and test group Ⅰ (P<0.05). Crude protein digestibility of piglets in test groups Ⅰ, Ⅱ and Ⅲ was significantly higher than that in control group (P<0.05). Gross energy digestibility of piglets in test groups Ⅱ and Ⅲ was significantly higher than that in control group (P<0.05). The results indicate that dietary supplementation of GOD can significantly improve serum antioxidant ability, reduce diarrhea rate and promote metabolism absorption of protein, glucose and lipid of weaned piglets, finally increase production performance. The suggested supplemental level of GOD is 180 U/kg.

Cite this article

HOU Zhenping, JIANG Guitao, WU Duanqin, LI Chuang, LIU Yanjie, WANG Haowei, DAI Qiuzhong . Effects of Glucose Oxidase on Growth Performance, Serum Biochemical Indexes and Antioxidant Function, and Nutrient Digestibility of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2017 , 29(10) : 3482 -3488 . DOI: 10.3969/j.issn.1006-267x.2017.10.008

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