Molecular Nutrition

Effects of Zearalenone on Reproductive Performance and Placenta Immunity Related Gene Expression of Sows

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  • 1. College of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China;
    2. Key Laboratory of Animal Immunology, Henan Academy of Academy of Agricultural Sciences, Key Laboratory of Animal Immunology of Ministry of Agriculture, Zhengzhou 450002, China;
    3. College of Life Science Technology, Gansu Agriculture University, Lanzhou 730070, China

Received date: 2017-04-15

  Online published: 2017-09-28

Abstract

This experiment was to conducted to study the effects of dietary zearalenone (ZEN) on reproductive performance and placenta immunity related gene expression of sows. Forty 30 days gestation sows with similar parity and 200 kg body weight were randomly divided into 2 groups with 20 replicates per group and 1 pig per replicate. Pigs in the control group were fed a basal diet, while others in the experimental group were fed the basal diet supplemented with 1.5 mg/kg ZEN. The experiment lasted for 74 days. The results showed that compared with the control group:1) dietary supplemented with ZEN significantly increased the number of stillborn piglets and number of weak born piglets of pregnant sows (P<0.05), and significantly decreased the number of total born piglets of sows (P<0.05); 2) dietary supplemented with ZEN significantly increased the serum progesterone content of pregnant sows (P<0.05); 3) dietary supplemented with ZEN significantly increased the expressions of Toll-like receptor-2 (TLR-2) and progesterone receptor (PGR) in placenta of pregnant sows (P<0.05). In conclusion, dietary supplemented with 1.5 mg/kg ZEN can significantly decrease the number of total born piglets, and significantly increase the number of stillborn piglets and number of weak born piglets of pregnant sows. Dietary low level of ZEN still has adverse effect on reproductive performance of sows.

Cite this article

WANG Xiangsheng, SUN Yaning, RUAN Chongmei, ZHANG Quanwei, ZHANG Yong, HU Xiaofei . Effects of Zearalenone on Reproductive Performance and Placenta Immunity Related Gene Expression of Sows[J]. Chinese Journal of Animal Nutrition, 2017 , 29(10) : 3696 -3702 . DOI: 10.3969/j.issn.1006-267x.2017.10.032

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