Molecular Nutrition

Research Advancement of Innate Immunity and Pattern Recognition Receptors

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  • College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China

Received date: 2017-05-18

  Online published: 2017-10-31

Abstract

Innate immunity is the first defense against the pathogen aggression. Toll-like receptors (TLRs), nucleotide-binding oligomerization domain-like receptors (NLRs) and RIG-1-like receptors (RLRs) serve as pattern recognition receptors (PRRs) that recognize different but overlapping microbial components, formation of the corresponding signal transduction to generate immune response. The study on innate immunity and PRRs has received grade advancement in recent years that provides a way for the treatment of immune related diseases. This review summarized characteristics of PRRs and the interplay across different PRR signaling pathways.

Cite this article

HE Shaoping, HE Jianhua, CHEN Jiayi, CHEN Fu, OU Shuqi . Research Advancement of Innate Immunity and Pattern Recognition Receptors[J]. Chinese Journal of Animal Nutrition, 2017 , 29(11) : 3844 -3851 . DOI: 10.3969/j.issn.1006-267x.2017.11.002

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