[1] 卢德勋.国际动物营养学发展形势和我们的任务[J].畜牧与饲料科学,2010,31(6/7):449-453.
[2] DRACKLER J K,DONKIN S S,REYNOlLDS C K.Major advances in fundamental dairy cattle nutrition[J].Journal of Dairy Science,2006,89(4):1324-1336.
[3] CORELLA D,COLETLL O,MATTINGLEY G,et al.Utilizing nutritional genomics to tailor diets for the prevention of cardiovascular disease:a guide for upcoming studies and implementations[J].Expert Review of Molecular Diagnostics,2017,17(5):495-513.
[4] GARCIA C J,GARCÍA-VILLALBA R,GARRIDO Y,et al.Untargeted metabolomics approach using UPLC-ESI-QTOF-MS to explore the metabolome of fresh-cut iceberg lettuce[J].Metabolomics,2016,12(8):138.
[5] SUN H Z,WANG D M,WANG B,et al.Metabolomics of four biofluids from dairy cows:potential biomarkers for milk production and quality[J].Journal of Proteome Research,2015,14(2):1287-1298.
[6] NICHOLSON J K,CONNELLY J,LINDON J C,et al.Metabonomics:a platform for studying drug toxicity and gene function[J].Nature Reviews Drug Discovery,2002,1(2):153-161.
[7] MVLLER M,KERSTEN S.Nutrigenomics:goals and strategies[J].Nature Reviews Genetics,2003,4(4):315-322.
[8] LANE A N,FAN T W M.NMR-based stable isotope resolved metabolomics in systems biochemistry[J].Archives of Biochemistry NMR,2017,49(3/4):267-280.
[9] GARCÍA-VILLALBA R,TOMÁS-BARBERÁN F A,FANÇA-BERTHON P,et al.Targeted and untargeted metabolomics to explore the bioavailability of the secoiridoids from a seed/fruit extract (
Fraxinus angustifolia Vahl) in human healthy volunteers:a preliminary study[J].Molecules,2015,20(12):22202-22219.
[10] VELENOSI T J,HENNOP A,FEERE D A,et al.Untargeted plasma and tissue metabolomics in rats with chronic kidney disease given AST-120[J].Scientific Reports,2016,6:22526.
[11] TAYLOR J,KING R D,ALTMANN T,et al.Application of metabolomics to plant genotype discrimination using statistics and machine learning[J].Bioinformatics,2002,18(Suppl 2):241-248.
[12] FANG N H,YU S G,RONIS M J J,et al.Matrix effects break the LC behavior rule for analytes in LC-MS/MS analysis of biological samples[J].Experimental Biology and Medicine,2015,240(4):488-497.
[13] WENNER M I,MAKER G L,DAWSON L F,et al.The potential of metabolomic analysis techniques for the characterisation of α1-adrenergic receptors in cultured N1E-115 mouse neuroblastoma cells[J].Cytotechnology,2016,68(4):1561-1575.
[14] STOYANOVA R,BROWN T R.NMR spectral quantitation by principal component analysis:Ⅲ.A generalized procedure for determination of lineshape variations[J].Journal of Magnetic Resonance,2002,154(2):163-175.
[15] WELJIE A M,DOWLATABADI R,MILLER B J,et al.An inflammatory arthritis-associated metabolite biomarker pattern revealed by
1H-NMR spectroscopy[J].Journal of Proteome Research,2007,6(9):3456-3464.
[16] MARKLEY J L,BRVSCHWEILER R,EDISON A S,et al.The future of NMR-based metabolomics[J].Current Opinion in Biotechnology,2017,43:34-40.
[17] PUDAKALAKATTI S M,DUBEY A,JAIPURIA G,et al.A fast NMR method for resonance assignments:application to metabolomics[J].Journal of Biomolecular NMR,2014,58(3):165-173.
[18] SZOBOSZLAI N,GUO X H,OZOHANICS O,et al.Determination of energy metabolites in cancer cells by porous graphitic carbon liquid chromatography electrospray ionization mass spectrometry for the assessment of energy metabolism[J].Analytica Chimica Acta,2014,819:108-115.
[19] LIU M L,ZHENG P,LIU Z,et al.GC-MS based metabolomics identification of possible novel biomarkersforschizophrenia in peripheral blood mononuclear cells[J].Molecular BioSystems,2014,10(9):2398-2406.
[20] PERROT-DOCKÈS M,LÉVY-LEDUC C,CHIQUET J,et al.A multivariate variable selection approach for analyzing LC-MS metabolomics data[J/OL].[2017-06-08] [2017-05-31].https://arxiv.org/abs/1704.00076.
[21] VINAIXA M,SCHYMANSKI E L,NEUMANN S,et al.Mass spectral databases for LC/MS-and GC/MS-based metabolomics:State of the field and future prospects[J].TrAC:Trends in Analytical Chemistry,2016,78:23-35.
[22] DAGHIR-WOJTKOWIAK E,WICZLING P,WASZCZUK-JANKOWSKA M,et al.Multilevel pharmacokinetics-driven modeling of metabolomics data[J].Metabolomics,2017,13(3):31.
[23] WANG Y,TAO Y,LIN Y J,et al.Integrated analysis of serum and liver metabonome in liver transplanted rats by gas chromatography coupled with mass spectrometry[J].Analytica Chimica Acta,2009,633(1):65-70.
[24] BERTRAM H C,MALMENDAL A,PETERSEN B O,et al.Effect of magnetic field strength on NMR-based metabonomic human urine data.Comparative study of 250,400,500,and 800 MHz[J].Analytical Chemistry,2007,79(18):7110-7115.
[25] ZHANG Q W,WU H Y,WEN C C,et al.Metabolic changes in rats after intragastric administration of MGCD0103(
Mocetinostat),a HDAC class Ⅰ inhibitor[J].International Journal of Clinical and Experimental Pathology,2015,8(8):9320-9325.
[26] XIA J,SINELNIKOV I V,HAN B,et al.Metabo Analyst 3.0-making metabolomics more meaningful[J].Nucleic Acids Research,2015,43(W1):W251-W257.
[27] 肖英平.早期断奶仔猪血清代谢组学研究及谷氨酰胺对日粮消化吸收和代谢的影响[D].博士学位论文.杭州:浙江大学,2012.
[28] SUN J H,MONAGAS M,JANG S,et al.A high fat,high cholesterol diet leads to changes in metabolite patterns in pigs-A metabolomic study[J].Food Chemistry,2015,173:171-178.
[29] 聂存喜,张文举,闫理东,等.基于棉籽粕源发酵饲料的鸡血浆代谢组学研究[J].畜牧兽医学报,2013,44(5):737-744.
[30] 王小雪.代谢组学方法研究家猫在不同营养干预下机体的代谢应答[D].硕士学位论文.上海:上海交通大学,2008.
[31] 林刚.宫内生长受限猪胎盘磷酸戊糖途径受损及其营养调控的研究[D].博士学位论文.北京:中国农业大学,2014.
[32] 霍文婕.高谷物日粮改变山羊瘤胃代谢的微生物学机制研究[D].博士学位论文.南京:南京农业大学,2014.
[33] 时梦.后备母猪适宜净能需要量的研究[D].博士学位论文.北京:中国农业大学,2017.
[34] METZLER-ZEBELI B U,ERTL R,KLEIN D,et al.Explorative study of metabolic adaptations to various dietary calcium intakes and cereal sources on serum metabolome and hepatic gene expression in juvenile pigs[J].Metabolomics,2015,11(3):545-558.
[35] NOGUCHI Y,ZHANG Q W,SUGIMOTO T,et al.Network analysis of plasma and tissue amino acids and the generation of an amino index for potential diagnostic use[J].The American Journal of Clinical Nutrition,2006,83(2):513S-519S.
[36] ZHOU L P,FANG L D,SUN Y,et al.Effects of the dietary protein level on the microbial composition and metabolomic profile in the hindgut of the pig[J].Anaerobe,2016,38:61-69.
[37] RUAN Z,YANG Y H,WEN Y M,et al.Metabolomic analysis of amino acid and fat metabolism in rats with l-tryptophan supplementation[J].Amino Acids,2014,46(12):2681-2691.
[38] BOVO S,MAZZONI G,GALIMBERTI G,et al.Metabolomics evidences plasma and serum biomarkers differentiating two heavy pig breeds[J].Animal,2016,10(10):1741-1748.
[39] WANG X R,FANG C K,HE J H,et al.Comparison of the meat metabolite composition of
Linwu and Pekin ducks using 600 MHz
1H nuclear magnetic resonance spectroscopy[J].Poultry Science,2017,96(1):192-199.
[40] TRABI M,KELLER M D,JONSSON N N.NMR-based metabonomics of bovine blood:an investigation into the effects of long term storage on plasma samples[J].Metabolomics,2013,9(5):1041-1047.
[41] JUNG Y,LEE J,KWON J,et al.Discrimination of the geographical origin of beef by
1H NMR-based metabolomics[J].Journal of Agricultural and Food Chemistry,2010,58(19):10458-10466.
[42] REGAL P,ANIZAN S,ANTIGNAC J P,et al.Metabolomic approach based on liquid chromatography coupled to high resolution mass spectrometry to screen for the illegal use of estradiol and progesterone in cattle[J].Analytica Chimica Acta,2011,700(1/2):16-25.
[43] LU C F,WANG Y M,SHENG Z G,et al.NMR-based metabonomic analysis of the hepatotoxicity induced by combined exposure to PCBs and TCDD in rats[J].Toxicology and Applied Pharmacology,2010,248(3):178-184.
[44] 许梅燕.添加色素在鸡及其产品中代谢组学的GC-MS分析研究[D].硕士学位论文.长春:长春理工大学,2012.
[45] 施寿荣.肉鸡腹水综合征的代谢组学和转录组学研究[D].博士学位论文.北京:中国农业大学,2014.
[46] 孙玲伟,包凯,李影,等.奶牛临床和亚临床酮病的血浆代谢组学研究[J].中国农业科学,2014,47(8):1588-1599.
[47] BERTRAM H C,MALMENDAL A,NIELSEN N C,et al.NMR-based metabonomics reveals that plasma betaine increases upon intake of high-fiber rye buns in hypercholesterolemic pigs[J].Molecular Nutrition and Food Research,2009,53(8):1055-1062.
[48] HAILEMARIAM D,MANDAL R,SALEEM F,et al.Identification of predictive biomarkers of disease state in transition dairy cows[J].Journal of Dairy Science,2014,97(5):2680-2693.
[49] 田忠.糖尿病小型猪急性心肌缺血代谢组学研究[D].硕士学位论文.北京:北京协和医学院,2013.
[50] XIONG Y,DONG S,ZHAOX,et al.Gene expressions
