Molecular Nutrition

Safety Evaluation of Enterococcus faecium WEI-10 on Weaned Piglets

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  • Beijing Daweijia Biotechnology Co., Ltd., Beijing Engineering Laboratory of Probiotics Key Technology Development, Beijing Engineering and Technology Research Center of Feeding Probiotics, Beijing 100085, China

Received date: 2017-05-26

  Online published: 2017-12-04

Abstract

In order to evaluate the safety of study Enterococcus faecium WEI-10 on weaned piglets, Enterococcus faecium WEI-10 was added in diet to determine the effects on activity condition, diarrhea score, growth performance, histopathology changes and bacteremia in weaned piglets. Two batch tests were designed. In each batch test, two hundred and fifty-three crossbred (Large White×Landrace×Duroc) weaned piglets at 26 days of age with average body weight of (7.44±1.02) kg and (8.11±1.51) kg, respectively, were randomly assigned to two groups. Control group was fed only with a basal diet without antibiotics and probiotics, and test group was fed the basal diet supplemented with Enterococcus faecium WEI-10 (1×108 and 1×107 CFU Enterococcus faecium WEI-10 per gram of basal diet in two batch tests, respectively). The trial lasted for 38 days. The results showed as follows:1) there were no significant differences between test group and control group in activity score, average daily gain and feed to gain ratio in two batch tests (P>0.05). 2) Compared with control groups, diarrhea score of test groups on day 5, 10 and 38 was significantly decreased (P<0.05); on day 38, diarrhea score of test groups reduced to 0, while that of control groups was about 0.6. 3)Bacteremia and pathology changes in heart, liver, spleen, lung, kidney, duodenum and jejunum did not occur in test groups and control groups of two batch tests. The study indicates that Enterococcus faecium WEI-10 has no safety problems and can reduce diarrhea of weaned piglets.

Cite this article

FENG Yuanyuan, QIAO Lin, YAO Hongming, JIE Linxia, GAO Changbin, LIU Rui . Safety Evaluation of Enterococcus faecium WEI-10 on Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2017 , 29(12) : 4588 -4596 . DOI: 10.3969/j.issn.1006-267x.2017.12.041

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