Molecular Nutrition

Effects of Yeast Mannan Oligosaccharides on Growth Performance, Serum Immune, Inflammatory and Antioxidant Indicators of Mongolian Sheep

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  • College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China

Received date: 2017-06-19

  Online published: 2018-01-04

Abstract

This experiment was conducted to investigate the effects of yeast mannan oligosaccharides on growth performance, serum immune, inflammatory and antioxidant indicators of Mongolian sheep. Eighteen Mongolian sheep with good body condition and similar body weight[(28.91±1.81) kg] were randomly allotted to three groups with six sheep per group. Sheep in control group were fed a basal diet, and those in mannan oligosaccharides group and rumensin group were fed the basal diet supplemented with 0.1% yeast mannan oligosaccharides (the supplemental level was on concentrated, the same as below) and 0.015% rumensin, respectively. The duration of the experiment was 70 days (the pre-test period was 10 days and the test period was 60 days). On the 1st and 30th day, dietary concentrated to forage ratio was 4:6, while on the 31st to 60th day, it was gradually turned into 7:3. On the 1st, 30th and 60th day of test period, empty stomach body weight was tested and serum was collected to determine concentrations of immunoglobulin M (IgM), lipopolysaccharide binding protein (LBP), interleukin 6 (IL-6), serum amyloid A (SAA) and nitric oxide (NO), total antioxidant capacity (T-AOC), and the activities of total superoxide dismutase (T-SOD) and glutathione peroxidase (GSH-Px). The results showed as follows:1) compared with control group, growth performance of Mongolian sheep (high concentrate feeding mode) was significantly increased by the addition of mannan oligosaccharides and rumensin, which showed significant increases in body weight (the 60th day) and average daily gain (P<0.05), and a significant decrease in feed/gain (P<0.05); furthermore on 1st to 30th day, stage daily gain in mannan oligosaccharides group was significantly higher than that in the other two groups (P<0.05), while on 31st to 60th day, rumensin group was significantly higher than control group (P<0.05). 2) Compared with control group, on 30th day, serum IgM concentration, LBP concentration and T-SOD activity in mannan oligosaccharides group was significantly increased (P<0.05); on 60th day, serum SAA concentration in mannan oligosaccharides group was significantly increased (P<0.05), while serum T-AOC and GSH-Px activity in mannan oligosaccharides group were significantly decreased (P<0.05), and serum T-AOC in rumensin group was also significantly decreased (P<0.05). It is concluded that addition of yeast mannan oligosaccharides can improve growth performance, serum immune and antioxidant functions of Mongolian sheep feeding high concentrate diet, and the effects are similar to rumensin; mannan oligosaccharides shows better effect when dietary concentrate to forage ratio is 4:6.

Cite this article

XIE Mingxin, WANG Hairong, YANG Jinli, WANG Guichao, LI Jingjing, LI Changrui . Effects of Yeast Mannan Oligosaccharides on Growth Performance, Serum Immune, Inflammatory and Antioxidant Indicators of Mongolian Sheep[J]. Chinese Journal of Animal Nutrition, 2018 , 30(1) : 219 -226 . DOI: 10.3969/j.issn.1006-267x.2018.01.027

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