[1] CHELOMBIT'KO V A,MURAV,EVA D A.Bocconia microcarpe,source of the alkaloids cheleritrine and sanguinarine[J].Pharmaceutical Chemistry Journal,1968,2(2):103-105.
[2] GODOWSKI K C,WOLFF E D,THOMPSON D M,et al.Whole mouth microbiota effects following subgingival delivery of sanguinarium[J].Journal of Periodontology,1995,66(10):870-877.
[3] LENFELD J,KROUTIL M,MARŠÁLEK E,et al.Antiinflammatory activity of quaternary benzophenanthridine alkaloids from
Chelidonium majus[J].Planta Medica,1981,43(10):161-165.
[4] CHATURVEDI M M,KUMAR A,DARNAY B G,et al.Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-κB activation,IκBα phosphorylation,and degradation[J].Journal of Biological Chemistry,1997,272(48):30129-30134.
[5] NIU X F,FAN T,LI W F,et al.The anti-inflammatory effects of sanguinarine and its modulation of inflammatory mediators from peritoneal macrophages[J].European Journal of Pharmacology,2012,689(1/2/3):262-269.
[6] P ěN?ÍKOVÁK,KOLLÁR P,MVLLER ZÁVALOVÁ V M,et al.Investigation of sanguinarine and chelerythrine effects on LPS-induced inflammatory gene expression in THP-1 cell line[J].Phytomedicine,2012,19(10):890-895.
[7] LI H W,ZHAI Z J,LIU G W,et al.Sanguinarine inhibits osteoclast formation and bone resorption via suppressing RANKL-induced activation of NF-κB and ERK signaling pathways[J].Biochemical and Biophysical Research Communications,2013,430(3):951-956.
[8] LI W F,LI H N,YAO H,et al.Pharmacokinetic and anti-inflammatory effects of sanguinarine solid lipid nanoparticles[J].Inflammation,2014,37(2):632-638.
[9] NIU X F,FAN T,LI W F,et al.Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice[J].Toxicology and Applied Pharmacology,2013,267(3):256-265.
[10] LI W F,LI H N,MU Q L,et al.Protective effect of sanguinarine on LPS-induced endotoxic shock in mice and its effect on LPS-induced COX-2 expression and COX-2 associated PGE2 release from peritoneal macrophages[J].International Immunopharmacology,2014,22(2):311-317.
[11] VRBA J,HRBÁ? J,ULRICHOVÁ J,et al.Sanguinarine is a potent inhibitor of oxidative burst in DMSO-differentiated HL-60 cells by a non-redox mechanism[J].Chemico-Biological Interactions,2004,147(1):35-47.
[12] LIU Y,JIAO R,MA Z G,et al.Sanguinarine inhibits angiotensin Ⅱ induced apoptosis in H9c2 cardiac cells via restoring reactive oxygen speciesmediated decreases in the mitochondrial membrane potential[J].Molecular Medicine Reports,2015,12(3):3400-3408.
[13] VRBA J,OROLINOVA E,ULRICHOVA J.Induction of heme oxygenase-1 by
Macleaya cordata extract and its constituent sanguinarine in RAW264.7 cells[J].Fitoterapia,2012,83(2):329-335.
[14] 姚雯.血根碱抗氧化活性及其对MKN-45和TE-1癌细胞凋亡的研究[D].硕士学位论文.杨凌:西北农林科技大学,2014.
[15] 漆俊.血根碱对大鼠肠平滑肌细胞活性和细胞凋亡的影响[D].硕士学位论文.长沙:湖南农业大学,2012.
[16] 王慧.血根碱对大鼠小肠平滑肌收缩的抑制作用及信号传导通路研究[D].博士学位论文.长沙:湖南农业大学,2012.
[17] WANG H,YIN G H,YU C H,et al.Inhibitory effect of sanguinarine on PKC-CPI-17 pathway mediating by muscarinic receptors in dispersed intestinal smooth muscle cells[J].Research in Veterinary Science,2013,95(3):1125-1133.
[18] 李杰,伍树松,熊兴耀,等.博落回生物碱对猪肠上皮细胞增殖的影响[J].动物营养学报,2014,26(6):1632-1637.
[19] VRUBLOVA E,VOSTÁLOVÁ J,EHRMANN J,et al.The phytogenic feed additive modulates dextran sulfate sodium-induced colitis in rats[J].Veterinární Medicína,2010,55(12):610-618.
[20] DRSATA J,ULRICHOVÁ J,WALTEROVÁ D.Sanguinarine and chelerythrine as inhibitors of aromatic amino acid decarboxylase[J].Journal of Enzyme Inhibition,1996,10(4):231-237.
[21] GU S,YANG X C,XIANG X Y,et al.Sanguinarine-induced apoptosis in lung adenocarcinoma cells is dependent on reactive oxygen species production and endoplasmic reticulum stress[J].Oncology Reports,2015,34(2):913-919.
[22] WANG Y,ZHANG B L,LIU W,et al.Noninvasive bioluminescence imaging of the dynamics of sanguinarine induced apoptosis via activation of reactive oxygen species[J].Oncotarget,2016,7(16):22355-22367.
[23] LEE T K,PARK C,JEONG S J,et al.Sanguinarine induces apoptosis of human oral squamous cell carcinoma kb cells via inactivation of the PI3K/Akt signaling pathway[J].Drug Development Research,2016,77(5):227-240.
[24] RAHMAN A,THAYYULLATHIL F,PALLICHANKANDY S,et al.Hydrogen peroxide/ceramide/Akt signaling axis play a critical role in the antileukemic potential of sanguinarine[J].Free Radical Biology and Medicine,2016,96:273-289.
[25] 张鸿.血根碱对细胞的增殖抑制和凋亡诱导作用研究[D].硕士学位论文.呼和浩特:内蒙古工业大学,2010.
[26] MALÍKOVÁ J,ZDA ?ILOVÁ A,HLOBILKOVÁ A,et al.The effect of chelerythrine on cell growth,apoptosis,and cell cycle in human normal and cancer cells in comparison with sanguinarine[J].Cell Biology and Toxicology,2006,22(6):439-453.
[27] VOGT A,TAMEWITZ A,SKOKO J,et al.The benzo[c]phenanthridine alkaloid,sanguinarine,is a selective,cell-active inhibitor of mitogen-activated protein kinase phosphatase-1[J].Journal of Biological Chemistry,2005,280(19):19078-19086.
[28] LOPUS M,PANDA D.The benzophenanthridine alkaloid sanguinarine perturbs microtubule assembly dynamics through tubulin binding.A possible mechanism for its antiproliferative activity[J].FEBS Journal,2006,273(10):2139-2150.
[29] DZINK J L,SOCRANSKY S S.Comparative
in vitro activity of sanguinarine against oral microbial isolates[J].Antimicrobial Agents and Chemotherapy,1985,27(4):663-665.
[30] 刘靖.博落回生物碱对黄羽肉鸡生长的影响[D].硕士学位论文.长沙:湖南农业大学,2010.
[31] 苏红,白华,骆延波,等.Sangrovit对临床多抗菌株的抑制作用及对肉鸡生长促进的饲养试验[J].饲料工业,2012,33(7):27-33.
[32] HAMOUD R,REICHLING J,WINK M.Synergistic antibacterial activity of the combination of the alkaloid sanguinarine with EDTA and the antibiotic streptomycin against multidrug resistant bacteria[J].Journal of Pharmacy and Pharmacology,2015,67(2):264-273.
[33] OBIANG-OBOUNOU B W,KANG O H,CHOI J G,et al.The mechanism of action of sanguinarine against methicillin-resistant
Staphylococcus aureus[J].The Journal of Toxicological Sciences,2011,36(3):277-283.
[34] HAMOUD R,REICHLING J,WINK M.Synergistic antimicrobial activity of combinations of sanguinarine and EDTA with vancomycin against multidrug resistant bacteria[J].Drug Metabolism Letters,2014,8(2):119-128.
[35] OBIANG-OBOUNOU B W,KANG O H,CHOI J G,et al.
In vitro potentiation of ampicillin,oxacillin,norfloxacin,ciprofloxacin,and vancomycin by sanguinarine against methicillin-resistant
Staphylococcus aureus[J].Foodborne Pathogens and Disease,2011,8(8):869-874.
[36] BEURIA T K,SANTRA M K,PANDA D.Sanguinarine blocks cytokinesis in bacteria by inhibiting FtsZ assembly and bundling[J].Biochemistry,2005,44(50):16584-16593.
[37] 王静慧.血根碱对细菌生物被膜的作用研究[D].硕士学位论文.杭州:浙江工商大学,2012.
[38] YANG X J,MIAO F,YAO Y,et al.
In vitro antifungal activity of sanguinarine and chelerythrine derivatives against phytopathogenic fungi[J].Molecules,2012,17(12):13026-13035.
[39] WATAMOTO T,EGUSA H,SAWASE T,et al.Screening of pharmacologically active small molecule compounds identifies antifungal agents against
Candida biofilms[J].Frontiers in Microbiology,2015,6:1453.
[40] BIANCO F,BASINI G,GRASSELLI F.The plant alkaloid sanguinarine affects swine granulosa cell activity[J].Reproductive Toxicology,2006,21(3):335-340.
[41] BASINI G,SANTINI S E,BUSSOLATI S,et al.The plant alkaloid sanguinarine is a potential inhibitor of follicular angiogenesis[J].Journal of Reproduction and Development,2007,53(3):573-579.
[42] CHAN W H.Hazardous effects of sanguinarine on maturation of mouse oocytes,fertilization,and fetal development through apoptotic processes[J].Environmental Toxicology,2015,30(8):946-955.
[43] CHAN W H.Embryonic toxicity of sanguinarine through apoptotic processes in mouse blastocysts[J].Toxicology Letters,2011,205(3):285-292.
[44] 满意,张春勇,李美荃,等.博落回提取物对早期断奶仔猪生长性能和血清免疫参数的影响[J].动物营养学报,2013,25(1):126-132.
[45] 何夏阳.血根碱对断奶仔猪生长性能、养分消化率和血液生化指标的影响[D].硕士学位论文.长沙:湖南农业大学,2010.
[46] GUDEV D,RALCHEVA S P,MONEVA P,et al.Effect of supplemental Sangrovit on some biochemical indices and leukocytes phagocytic activity in growing pigs[J].Archiva Zootechnica,2004,7:123-134.
[47] KANTAS D,PAPATSIROS V G,TASSIS P D,et al.The effect of a natural feed additive (
Macleaya cordata),containing sanguinarine,on the performance and health status of weaning pigs[J].Journal of Animal Science,2015,86(1):92-98.
[48] 贺喜,岳龙,张石蕊,等.低蛋白质饲粮中植物源血根碱替代色氨酸对仔猪门静脉血浆流率及氨基酸代谢的影响[J].动物营养学报,2015,27(6):1861-1867.
[49] ARTUSO-PONTE V,ABLEY M,MOLLA B,et al.Activity of Sangrovit against
Lawsonia intracellularis in grower pigs and its impact on gut physiology and host immunity[A/OL].Retrieved from the University of Minnesota Digital Conservancy,2011.http://hdl.handle.net/11299/152107.
[50] VIEIRA S L,BERRES J,REIS R N,et al.Studies with sanguinarine like alkaloids as feed additive in broiler diets[J].Revista Brasileira de Ciência Avícola,2008,10(1):28-33.
[51] LEE K W,KIM J S,OH S T,et al.Effects of dietary sanguinarine on growth performance,relative organ weight,cecal microflora,serum cholesterol level and meat quality in broiler chickens[J].The Journal of Poultry Science,2015,52(1):15-22.
[52] KHADEM A,SOLER L,EVERAERT N,et al.Growth promotion in broilers by both oxytetracycline and
Macleaya cordata extract is based on their anti-inflammatory properties[J].British Journal of Nutrition,2014,112(7):1110-1118.
[53] KARIMI M,FOROUDI F,ABEDINI M R.Effect of sangrovit on performance and morphology of small intestine and immune response of broilers[J].Biosciences Biotechnology Research Asia,2014,11(2):855-861.
[54] YAKHKESHI S,RAHIMI S,GHARIB N K.The effects of comparison of herbal extracts,antibiotic,probiotic and organic acid on serum lipids,immune response,GIT microbial population,intestinal morphology and performance of broilers[J].Journal of Medicinal Plants,2011,10(37):80-95.
[55] VIEIRA S L,OYARZABAL O A,FREITAS D M,et al.Performance of broilers fed diets supplemented with sanguinarine-like alkaloids and organic acids[J].The Journal of Applied Poultry Research,2008,17(1):128-133.
[56] BAVARSADI M,MAHDAVI A H,ANSARI-MAHYARI S,et al.Effects of different levels of sanguinarine on antioxidant indices,immunological responses,ileal microbial counts and jejunal morphology of laying hens fed diets with different levels of crude protein[J].Journal of Animal Physiology and Animal Nutrition,2017,101(5):936-948.
[57] GAMMAZ H A,FAYEZ M M,ABDEL-NABY E A.Effect of sanguinarine and vitamins AD3E on growth performance in cyprinus carpio[J].SCVMJ,2010,15(1):27-44.
[58] RAWLING M D,MERRIFIELD D L,DAVIES S J.Preliminary assessment of dietary supplementation of Sangrovit on red tilapia (
Oreochromis niloticus) growth performance and health[J].Aquaculture,2009,294(1/2):118-122.
[59] IMANPOOR M R,ROOHI Z.Effects of Sangrovit-supplemented diet on growth performance,blood biochemical parameters,survival and stress resistance to salinity in the Caspian roach (
Rutilus rutilus) fry[J].Aquaculture Research,2016,47(9):2874-2880.
[60] ABDELNABY E A,MOHAMED M F,GAMMAZ H A K.Pharmacological studies of feed additives (sanguinarine and
Saccharomyces cerevisiae) on growth performance,haematological and intestinal bacterial count with challenge test by Aeromonas hydrophila in
Cyprinus carpio[J].Global Animal Science Journal,2013,1(1):1154-1172.
[61] ZHANG C,LING F,CHI C,et al.Effects of praziquantel and sanguinarine on expression of immune genes and susceptibility to Aeromonas hydrophila in goldfish (
Carassius auratus) infected with
Dactylogyrus intermedius[J].Fish & Shellfish Immunology,2013,35(4):1301-1308.
[62] RAIRAT T,CHUCHIRD N,LIMSUWAN C.Effect of Sangrovit WS on growth,survival and prevention of
Vibrio harveyi in rearing of pacific white shrimp (
Litopenaeus vannamei)[Z/OL].2013.http://anchan.lib.ku.ac.th/kukr/handle/003/24543.
[63] AGUILAR-HERNÁNDEZ J A,URÍAS-ESTRADA J D,LÓPEZ-SOTO M A,et al.Evaluation of isoquinoline alkaloid supplementation levels on ruminal fermentation,characteristics of digestion,and microbial protein synthesis in steers fed a high-energy diet[J].Journal of Animal Science,2016,94(1):267-274.
[64] ESTRADA-ANGULO A,AGUILAR-HERNÁNDEZ A,OSUNA-PÉREZ M,et al.Influence of quaternary benzophenantridine and protopine alkaloids on growth performance,dietary energy,carcass traits,visceral mass,and rumen health in finishing ewes under conditions of severe temperature-humidity index[J].Asian-Australasian Journal of Animal Sciences,2016,29(5):652-658.
