Molecular Nutrition

Effects of Blood Ammonia on Animal Health

Expand
  • 1. Beijing Animore Science & Technology Co., Ltd., Beijing 100193, China;
    2. National Feed Engineering Technology Research Center, Beijing 100193, China;
    3. Linzhou Animore Science & Technology Co., Ltd., Linzhou 456550, China

Received date: 2017-08-17

  Online published: 2018-02-02

Abstract

Ammonia is produced from metabolism of different tissues' amino acids and converted of gastrointestinal microbiological degradation, following absorbed into blood. High blood ammonia severely impairs animal health and gradually becomes paid close attention by animal husbandry. This review summarized metabolic characteristics and the effect on animal of blood ammonia, and provided data reference for blood ammonia detection in husbandry production.

Cite this article

AN Ya'nan, WU Fei, GUO Zhimin, WANG Chunping, ZHANG Haiyan, He Jinming . Effects of Blood Ammonia on Animal Health[J]. Chinese Journal of Animal Nutrition, 2018 , 30(2) : 491 -497 . DOI: 10.3969/j.issn.1006-267x.2018.02.012

References

[1] 罗献梅,甘玲.动物生物化学[M].重庆:西南师范大学出版社,2015:172-173.

[2] KIRK E.Amino acid and ammonia metabolism in liver diseases[J].JAMA,1936,107(25):2079.

[3] 汤其群.生物化学与分子生物学[M].上海:复旦大学出版社,2015:174-175.

[4] BARSOTTI R J.Measurement of ammonia in blood[J].The Journal of Pediatrics[J],2001,138(1):S11-S20.

[5] DAVIDOVICH A,BARTLEY E E,CHAPMAN T E,et al.Ammonia toxicity in cattle.Ⅱ.Changes in carotid and jugular blood components associated with toxicity[J].Journal of Animal Science,1977,44(4):702-709.  

[6] LEWIS D,HILL K J,ANNISON E F.Studies on the portal blood of sheep.1.Absorption of ammonia from the rumen of the sheep[J].Biochemical Journal,1957,66(4):587-592.  

[7] LOBLEY G E,WEIJS P J M,CONNELL A,et al.The fate of absorbed and exogenous ammonia as influenced by forage or forage-concentrate diets in growing sheep[J].British Journal of Nutrition,1996,76(2):231-248.  

[8] MILANO G D,LOBLEY G E.Liver nitrogen movements during short-term infusion of high levels of ammonia into the mesenteric vein of sheep[J].British Journal of Nutrition,2001,86(4):507-513.  

[9] MILANO G D,HOTSTON-MOORE A,LOBLEY G E.Influence of hepatic ammonia removal on ureagenesis,amino acid utilization and energy metabolism in the ovine liver[J].British Journal of Nutrition,2000,83(3):307-315.  

[10] LOSTE A,RAMOS J J,GARCÍA L,et al.High prevalence of ulcerative posthitis in rasa aragonesa rams associated with a legume-rich diet[J].Transboundary and Emerging Diseases,2005,52(4):176-179.

[11] 张桂芳,石蕊,姜发彬,等.不同精粗比日粮对泌乳奶山羊肝脏氨基酸代谢和产奶性能的影响[J].南京农业大学学报,2013,36(6):73-79.

[12] 应诗家,聂海涛,张国敏,等.不同营养水平对湖羊黄体期血液理化指标及卵泡发育的影响[J].中国农业科学,2011,45(8):1606-1612.

[13] 臧莹安,王艳玲,夏艳勋.不同来源的日粮蛋白质对山羊血清胃泌素水平的影响[J].中国草食动物,2002,22(3):6-9.

[14] HWANG S Y,LEE M J,PEH H C.Diurnal variations in milk and blood urea nitrogen and whole blood ammonia nitrogen in dairy cows[J].Asian-Australasian Journal of Animal Sciences,2001,14(12):1683-1689.  

[15] CLAYPOOL D W,PANGBOAN M C,ADAMS H P.Effect on dietary protein on high-producing dairy cows in early lactation1[J].Journal of Dairy Science,1980,63(5):833-837.  

[16] 彭春雨,孟庆翔,任丽萍,等.植物提取物对奶牛产奶性能和血液指标的影响[J].饲料研究,2011(7):8-10.

[17] 邓丽青.糊化淀粉尿素质量评价及其对奶牛氮代谢影响的研究[D].博士学位论文.北京:中国农业科学院,2011.

[18] PICCIONE G,GRASSO F,FAZIO F,et al.Influence of different schedules of feeding on daily rhythms of blood urea and ammonia concentration in cows[J].Biological Rhythm Research,2007,38(2):133-139.  

[19] SINCLAIR K D,KURAN M,GEBBIE F E,et al.Nitrogen metabolism and fertility in cattle:Ⅱ.Development of oocytes recovered from heifers offered diets differing in their rate of nitrogen release in the rumen[J].Journal of Animal Science,2000,78(10):2670-2680.  

[20] HUNTINGTON G B,HARMON D L,KRISTENSEN N B,et al.Effects of a slow-release urea source on absorption of ammonia and endogenous production of urea by cattle[J].Animal Feed Science and Technology,2006,130(3):225-241.

[21] 江兰,孟庆翔,任丽萍,等.饲粮尿素添加水平对生长育肥牛生长性能和血液生化指标的影响[J].中国农业科学,2012,45(4):761-767.

[22] 查翘楚,张力凡,韩超,等.不同浓度枯草芽孢杆菌对蛋鸡血液生化指标的影响[J].中国饲料,2017(6):15-18.

[23] 佟建明,萨仁娜.持续、低剂量金霉素对肉仔鸡肠道微生物、血氨、尿酸和生产性能的影响[J].畜牧兽医学报,2001,32(5):403-409.

[24] 孙得发,徐秀容,张宏福,等.脲酶抑制剂对肉仔鸡代谢氨浓度的影响[J].西北农林科技大学学报:自然科学版,2002,30(2):59-62.

[25] 宋弋,王忠,姚中磊,等.氨气对肉鸡生产性能、血氨和尿酸的影响研究[J].中国家禽,2008,30(13):10-12,16.

[26] 程时军,马立保,张伟.溶菌酶对肉鸡肠黏膜形态、微生物数量及血氨浓度的影响[J].饲料工业,2009,30(20):13-16.

[27] 许金华,谭翔文,印遇龙,等.果胶对猪血氨的影响[J].南华大学学报·医学版,2005,33(2):188-191.

[28] 孙召君.瓜氨酸添加水平对哺乳仔猪生长性能及相关理化指标的影响[D].硕士学位论文.保定:河北农业大学,2012.

[29] 汪澎.破壁全酵母粉完全替代血浆蛋白在仔猪教槽料中的应用评价研究[D].硕士学位论文.长沙:湖南农业大学,2015.

[30] 陈楠.N-氨甲酰谷氨酸对哺乳仔猪生长性能及相关理化指标的影响[D].硕士学位论文.保定:河北农业大学,2012.

[31] 孙玉丽.L-亮氨酸对新生哺乳仔猪肠道发育及氨基酸转运影响的研究[D].博士学位论文.北京:中国农业大学,2015.

[32] 黄飞若.猪营养代谢与表观遗传学[M].北京:化学工业出版社,2016.

[33] 江雪梅.饲粮添加L-精氨酸或N-氨甲酰谷氨酸对母猪繁殖性能及血液参数的影响[D].硕士学位论文.雅安:四川农业大学,2011.

[34] 刘俊锋,吴琛,孔祥峰,等.精氨酸对妊娠环江香猪胎儿生长发育的影响[J].中国农业科学,2011,44(5):1040-1045.

[35] 刘星达,吴信,印遇龙,等.妊娠后期日粮中添加不同水平N-氨甲酰谷氨酸对母猪繁殖性能的影响[J].畜牧兽医学报,2011,42(11):1550-1555.

[36] 钱瑛.不同叶酸水平对母猪泌乳性能影响的研究[D].硕士学位论文.雅安:四川农业大学,2007.

[37] 周笑犁,印遇龙,孔祥峰,等.N-氨甲酰谷氨酸对环江香猪生长性能、营养物质消化率及血浆游离氨基酸含量的影响[J].动物营养学报,2011,23(11):1970-1975.

[38] 查伟.饲粮添加脯氨酸对环江香猪繁殖性能及其后代生长发育的影响[D].硕士学位论文.南昌:江西农业大学,2015.

[39] AÇIKALIN A,DI?EL N R,DIREK E Ç,et al.A rare cause of postpartum coma:isolated hyperammonemia due to urea cycle disorder[J].The American Journal of Emergency Medicine,2016,34(7):1324.e3-1324.e4.

[40] PARKER D S,LOMAX M A,SEAL C J,et al.Metabolic implications of ammonia production in the ruminant[J].Proceedings of the Nutrition Society,1995,54(2):549-563.  

[41] 林永焕.实用临床危重症诊疗学[M].北京:中国医药科技出版社,2000:522-523.

[42] 冯定远.饲料加工及检测技术[M].北京:中国农业出版社,2012:105-106.

[43] WILTON J C,GILL M,LOMAX M A.Uptake of ammonia across the liver of forage-fed cattle[J].Proceedings of the Nutrition Society,1988,47:153A.

[44] ANTONELLI A C,TORRES G A S,SOARES P C,et al.Ammonia poisoning causes muscular but not liver damage in cattle[J].Arquivo Brasileiro de Medicina Veterinária e Zootecnia,2007,59(1):8-13.  

[45] ANTONELLI A C,MORI C S,SOARES P C,et al.Experimental ammonia poisoning in cattle fed extruded or prilled urea:clinical findings[J].Brazilian Journal of Veterinary Research and Animal Science,2004,41(1):67-74.

[46] 蔡治华.氨对肉鸡增重的影响[J].安徽科技学院学报,2007,21(4):8-9.

[47] 鲁宁,易学武,谯仕彦.低蛋白日粮下赖氨酸水平对生长猪氮平衡和生长性能的影响[J].中国畜牧杂志,2011,47(5):34-38.

[48] 中华人民共和国农业部质量标准办公室.NY/T 388-1999畜禽场环境质量标准[S].北京:中国标准出版社,1999.
Outlines

/