Effects of Dietary Tributyrin and Nucleotide on Growth Performance, Serum Biochemical Indices and Intestinal Morphology of Weaned Piglets

ZHU Rongsheng, WANG Huaizhong, QI Bo, HUANG Baohua, SUN Shouli, WANG Jiancai, WEI Bin, HU Hongmei

doi:10.3969/j.issn.1006-267x.2018.02.036

2018 , Vol. 30 >Issue 2: 707 - 716

DOI: https://doi.org/10.3969/j.issn.1006-267x.2018.02.036

Molecular Nutrition

Effects of Dietary Tributyrin and Nucleotide on Growth Performance, Serum Biochemical Indices and Intestinal Morphology of Weaned Piglets

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1. Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Ji'nan 250100, China;
2. Key Laboratory of Disease Control and Animal Breeding of Shandong Province, Ji'nan 250100, China;
3. College of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China;
4. Ji'nan Haihua Organisma Science and Technology Co., Ltd., Ji'nan 250108, China

Received date: 2017-08-07

Online published: 2018-02-02

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Abstract

This experiment was conducted to investigate the effects of dietary tributyrin and nucleotide on growth performance, serum biochemical indices and intestinal morphology of weaned piglets. One hundred and sixty 21-day-old healthy Duroc×Landrace×Yorkshire piglets with about 8.4 kg body weight were randomly allotted into two groups with 10 replicates each and 8 pigs in each replicate. The piglets in the control group were fed a basal diet and in the experimental group were fed the basal diet supplemented with 0.20% tributyrin and 0.15% nucleotide, and the trial lasted for 38 days. The results showed as follows:1) compared with the control group, dietary tributyrin and nucleotide significantly increased the average daily gain (P<0.05), extremely significantly decreased the diarrhea rate (P<0.01), significantly increased the contents of immunoglobulin A, immunoglobulin G, immunoglobulin M and globulin in serum (P<0.05), and significantly decreased the diamine oxidase activity and glucose content in serum (P<0.05) of weaned piglets. 2) Compared with the control group, dietary tributyrin and nucleotide significantly increased villus height and the ratio of villus height to crypt depth in duodenum and jejunum (P<0.05), and significantly increased the activities of trypsin and maltase in jejunum contents (P<0.05) of weaned piglets. Thus, it can be seen that dietary tributyrin and nucleotide can improve the growth performance, enhance immunity of organism, reduce the damage of weaning stress to the intestine, increase digestive enzyme activity, and enhance digestion-absorption function of weaned piglets.

Key words： tributyrin; nucleotide; weaned piglets; growth performance; serum biochemical indices; intestinal morphology

Cite this article

ZHU Rongsheng, WANG Huaizhong, QI Bo, HUANG Baohua, SUN Shouli, WANG Jiancai, WEI Bin, HU Hongmei . Effects of Dietary Tributyrin and Nucleotide on Growth Performance, Serum Biochemical Indices and Intestinal Morphology of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2018 , 30(2) : 707 -716 . DOI: 10.3969/j.issn.1006-267x.2018.02.036

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