Effects of Dietary Different Glutamate and Aspartate Levels on Organ Indexes, Serum Biochemical Parameters and Hormone Contents of Piglets

LI Yuying, HAN Hui, WANG Qian, LI Chunyong, YAO Jiming, DENG Jinping, FAN Wenjun, LI Tiejun

doi:10.3969/j.issn.1006-267x.2018.04.013

2018 , Vol. 30 >Issue 4: 1303 - 1310

DOI: https://doi.org/10.3969/j.issn.1006-267x.2018.04.013

Molecular Nutrition

Effects of Dietary Different Glutamate and Aspartate Levels on Organ Indexes, Serum Biochemical Parameters and Hormone Contents of Piglets

Expand

1. Key Laboratory of Agri-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences;National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha 410125, China;
2. University of Chinese Academy of Sciences, Beijing 100039, China;
3. Department of Animal Science, Hunan Agriculture University, Changsha 410125, China;
4. Guangdong Wangda Group Academician Workstation for Clean Feed Technology Research and Development in Swine, Guangzhou 510663, China;
5. College of Animal Science of South China Agricultural University, Guangzhou 510642, China;
6. Hunan Co-Innovation Center of Animal Production Safety, Changsha 410128, China

Received date: 2017-09-30

Online published: 2018-04-03

Fold

Abstract

The aim of this study was to investigate the effects of dietary different glutamate and aspartate levels on organ indexes, serum biochemical parameters and hormone contents of piglets. Forty-two healthy crossbred weaned piglets (Duroc×Landrace×Yorkshire) were randomly divided into 6 groups with 7 replicates per group and 1 pig per replicate. Dietary glutamate and aspartate levels in the control group (NC group) were 2.9% and 1.5%, respectively; and dietary glutamate and aspartate levels in other groups were adjusted to 2.9% and 1.3% (LA group), 2.9% and 1.7% (HA group), 2.6% and 1.5% (LG group), 3.2% and 1.5% (HG group), 3.5% and 1.5% (HHG group) based on NC group diet, respectively. The experiment lasted for 21 days. The organ indexes, serum biochemical parameters and hormone contents were measured at the end of the experiment. The results showed as follows:1) dietary different glutamate and aspartate levels had no significant effects on organ indexes of piglets (P>0.05). 2) The serum triglyceride content of LA group and NC group was significantly lower than that of HA group (P<0.05), the serum triglyceride content of HG group and HHG group was significantly lower than that of LG group (P<0.05), the serum albumin content of LG group was significantly lower than that of NC group and HG group (P<0.05), the serum glucose content of LG group and HG group was significantly lower than that of HHG group (P<0.05). 3) The serum gastric inhibitory polypeptide content of HA group was significantly lower than that of LA group (P<0.05), the serum insulin content of LG group and HG group was significantly higher than that of HHG group (P<0.05), the serum glucagon content of LG group and HG group was significantly lower than that of HHG group (P<0.05), the serum growth hormone content of LG group and NC group was significantly lower than that of HHG group (P<0.05). It is concluded that dietary different glutamate and aspartate levels affect serum biochemical parameters and hormone contents, while has no significant effects on organ development of piglets.

Key words： acid amino acids; glutamate; aspartate; piglets; organ indexes; serum biochemical parameters; hormone

Cite this article

LI Yuying, HAN Hui, WANG Qian, LI Chunyong, YAO Jiming, DENG Jinping, FAN Wenjun, LI Tiejun . Effects of Dietary Different Glutamate and Aspartate Levels on Organ Indexes, Serum Biochemical Parameters and Hormone Contents of Piglets[J]. Chinese Journal of Animal Nutrition, 2018 , 30(4) : 1303 -1310 . DOI: 10.3969/j.issn.1006-267x.2018.04.013

References

[1] WU G Y,BAZER F W,DAVIS T A,et al.Important roles for the arginine family of amino acids in swine nutrition and production[J].Livestock Science,2007,112(1/2):8-22.

[2] BARB C R,CAMPBELL R M,ARMSTRONG J D,et al.Aspartate and glutamate modulation of growth hormone secretion in the pig:possible site of action[J].Domestic Animal Endocrinology,1996,13(1):81-90.

[3] WANG H B,LIU Y L,SHI H F,et al.Aspartate attenuates intestinal injury and inhibits TLR4 and NODs/NF-κB and p38 signaling in weaned pigs after LPS challenge[J].European Journal of Nutrition,2016,56(4):1433-1443.

[4] DUAN J L,YIN J,WU M M,et al.Dietary glutamate supplementation ameliorates mycotoxin-induced abnormalities in the intestinal structure and expression of amino acid transporters in young pigs[J].PLoS One,2014,9(11):e112357.

[5] 石海峰.天冬氨酸对脂多糖刺激断奶仔猪肠道损伤的调控作用[D].硕士学位论文.武汉:武汉轻工大学,2013.

[6] YIN J,LIU M,REN W,et al.Effects of dietary supplementation with glutamate and aspartate on diquat-induced oxidative stress in piglets[J].PLoS One,2015,10(4):e0122893.

[7] 吴苗苗,肖昊,印遇龙,等.谷氨酸对脱氧雪腐镰刀菌烯醇刺激下的断奶仔猪生长性能、血常规及血清生化指标变化的干预作用[J].动物营养学报,2013,25(7):1587-1594.

[8] 段杰林.酸性氨基酸缓解过氧化氢介导仔猪肠道氧化损伤机制研究[D].硕士学位论文.北京:中国科学院大学,2016.

[9] 王利剑.酸性和碱性氨基酸对断奶仔猪肠道氨基酸吸收及转运的影响研究[D].硕士学位论文.北京:中国科学院大学,2017.

[10] 陈明洪.呕吐毒素对育肥猪的影响及酸碱性氨基酸干预效应[D].硕士学位论文.长沙:湖南农业大学,2013.

[11] 彭彰智.谷氨酸对断奶仔猪的营养及肠道神经系统的影响[D].硕士学位论文.南昌:南昌大学,2012.

[12] 辛亮.不同日粮类型对仔猪生产性能及血清生化指标的影响[D].硕士学位论文.南京:南京农业大学,2013.

[13] 管武.理想氨基酸模式提高猪生产性能的机理[D].博士学位论文.北京:中国农业大学,1997.

[14] SHIRAYAMA H,OHSHIRO Y,KINJO Y,et al.Acute brain injury in hypoglycaemia-induced hemiplegia[J].Diabetic Medicine,2004,21(6):623-624.

[15] 杨小婷.饲粮蛋白、能量和纤维水平对圩猪生产性能、肉质和血清生化指标的影响[D].硕士学位论文.合肥:安徽农业大学,2013.

[16] 伍力,尹杰,何流琴,等.谷氨酰胺对缓解呕吐毒素刺激大鼠损伤作用的研究[J].肠外与肠内营养,2012,19(3):159-163.

[17] WATFORD M.Glutamine metabolism and function in relation to proline synthesis and the safety of glutamine and proline supplementation[J].Journal of Nutrition,2008,138(10):2003S-2007S.

[18] 宋燕青,张四喜,孙丽蕊,等.新一代降血糖药——肠促胰素[J].现代预防医学,2012,39(18):4887-4889.

[19] MAECHLER P,WOLLHEIM C B.Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis[J].Nature,1999,402(6762):685-689.

[20] MATSUNAGA N,KUBOTA I,ROH S G,et al.Effect of mesenteric venous volatile fatty acids (VFA) infusion on GH secretion in sheep[J].Endocrine Journal,1997,44(5):707-714.

Options

Outlines

模态框（Modal）标题

Abstract

Cite this article

References