Effects of 2-Hydroxy-4-(Methylthio) Butanoic Acid Isopropyl Ester Supplemental Level on Growth Performance, Nutrient Apparent Digestibility, Serum Biochemical Indices and Hormone Levels of Goats

CHEN Dong, LI Siyuan, CHEN Meiqing, ZHANG Peihua, LI Xinhua, MI Hui, SHEN Weijun, ZHANG Qian, LI Siwen

doi:10.3969/j.issn.1006-267x.2018.05.028

2018 , Vol. 30 >Issue 5: 1854 - 1863

DOI: https://doi.org/10.3969/j.issn.1006-267x.2018.05.028

Molecular Nutrition

Effects of 2-Hydroxy-4-(Methylthio) Butanoic Acid Isopropyl Ester Supplemental Level on Growth Performance, Nutrient Apparent Digestibility, Serum Biochemical Indices and Hormone Levels of Goats

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1. College of Animal Science and Technology, Agricultural University of Hunan, Changsha 410123, China;
2. Adisseo Life Science(Shanghai) Co., Ltd., Shanghai 200127, China;
3. Chaling Huiwang Agriculture and Animal Husbandry Development Co., Ltd., Zhuzhou 412000, China

Received date: 2017-11-03

Online published: 2018-05-06

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Abstract

This experiment was conducted to investigate the effects of 2-hydroxy-4-(methylthio) butanoic acid isopropyl ester (HMBi) supplementaal level on growth performance, nutrient apparent digestibility, serum biochemical indices and hormone levels of goats, aiming to determine the optimal supplemental level of HMBi in diets for goats. Thirty-six goats of about 2.5-month-old with an average body weight of (13.33±1.71) kg were randomly assigned to 4 groups with 3 replicates within each group, and one male goat and two female goats within each replicate. The goats in the 4 groups were fed the experimental diets containing 0 (control group), 0.05%, 0.10% and 0.20% HMBi on dry matter basis, respectively. The pre-experiment lasted for 10 days, and the formal experiment lasted for 40 days. The results showed as follows:1) the average daily gain of the control group, 0.05% group, 0.10% group and 0.20% group was 119.44, 140.56, 158.89 and 141.11 g/d, respectively. The 0.10% group had the greatest average daily gain, the lowest feed/gain of 4.82, and the best economic benefit. The average daily gain and gross returns of the 0.10% group were significantly greater than those of the control group (P<0.05). 2) No significant differences were found in apparent digestibility of dry matter, neutral detergent fiber, acid detergent fiber and digestible energy among groups (P>0.05). The apparent digestibility of crude protein of the 0.10% group was significantly higher than that of the control group (P<0.05). 3) There were no significant differences among all groups on the 1st day of the test in terms of the contents of urea nitrogen, glucose, triglycerides, total cholesterin, non-esterified fatty acid, total amino acid, and the levels of growth hormone and insulin-like growth factor-1 in serum (P>0.05). On the 31st day of the test, the serum triglycerides content of the 0.20% group was significantly higher than that of the other three groups (P<0.05); the serum total cholesterin content of the 0.20% group was significantly lower than that of the control group (P<0.05); the serum non-esterified fatty acid content of the 0.20% group was significantly higher than that of the control group (P<0.01) and the 0.05% group (P<0.05); the serum total amino acid content of the control group was significantly lower than that of the other groups (P<0.05); the serum growth hormone level of the control group was significantly lower than that of the 0.05% and 0.10% groups (P<0.05); the 0.20% group tended to increase serum growth hormone level compared with the control group (P=0.084); there was no significant difference in serum insulin-like growth factor-Ⅰ level among all groups (P>0.05). It is concluded that dietary supplementation of HMBi can improve the digestive utilization of protein, and then promote the growth of goats. Moreover, supplementation of 0.10% HMBi on the dry matter basis shows the best economic benefits.

Key words： goat; HMBi; supplemental level; growth performance; serum biochemical indices; hormone

Cite this article

CHEN Dong, LI Siyuan, CHEN Meiqing, ZHANG Peihua, LI Xinhua, MI Hui, SHEN Weijun, ZHANG Qian, LI Siwen . Effects of 2-Hydroxy-4-(Methylthio) Butanoic Acid Isopropyl Ester Supplemental Level on Growth Performance, Nutrient Apparent Digestibility, Serum Biochemical Indices and Hormone Levels of Goats[J]. Chinese Journal of Animal Nutrition, 2018 , 30(5) : 1854 -1863 . DOI: 10.3969/j.issn.1006-267x.2018.05.028

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