Molecular Nutrition

Effects of Acidifier and Oregano Oil Instead of Colistin Sulfate on Growth Performance, Diarrhea Rate and Caecal Microorganism Number of Weaned Piglets

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  • 1. Nutrition Feed Development Engineering Center of Jiangxi Province, Key Laboratory of Animal Nutrition in Jiangxi Province, Jiangxi Agricultural University, Nanchang 330045, China;
    2. Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China

Received date: 2017-11-03

  Online published: 2018-05-06

Abstract

This experiment was conducted to study the effects of acidifier and oregano oil instead of colistin sulfate on growth performance, diarrhea rate and caecal microorganism number of weaned piglets. The single factor design was used in the experiment, one hundred and twenty 26-day-old piglets with similar parity and body weight were randomly divided into three groups with five replicates in each group and eight piglets in each replicate. Diets in each group were contained 75 mg/kg chlortetracycline and 10 mg/kg enramycin. In addition, pigs in three groups were fed 0.10% acidifier+0.10% colistin sulfate, 0.15% acidifier and 0.15% acidifier+0.03% oregano oil experimental diets, respectively. The experiment lasted for 14 days. The results showed as follows:1) there were no significant differences on average daily gain, ratio of feed to gain and diarrhea rate of weaned piglets among all groups (P>0.05). Compared with 0.10% acidifier+0.10% colistin sulfate group and 0.15% acidifier+0.03% oregano oil group, the average daily feed intake of 0.15% acidifier group had a trend to increase (P=0.066). 2) The caecal Salmonella number of 0.10% acidifier+0.10% colistin sulfate group was significantly lower than that of 0.15% acidifier group (P<0.05), the numbers of Bifidobacteria and Lactobacillus in cecum of 0.15% acidifier+0.03% oregano oil group were significantly higher than those of 0.15% acidulant group (P<0.05), but there were no significant differences between the 0.15% acidifier+0.03% oregano oil group and 0.10% acidifier+0.10% colistin sulfate group (P>0.05). Accordingly, on the basis of the diets added 75 mg/kg chlortetracycline and 10 mg/kg enramycin, the effects of 0.15% acidifier or 0.15% acidifier+0.03% oregano oil on the growth performance of weaned piglets are similar to 0.10% colistin sulfate, 0.15% acidulant+0.03% oregano oil also can increase the number of beneficial bacteria in cecum which is similar to 0.10% colistin sulfate. So the diets added acidifier and oregano oil can replace the colistin sulfate use in weaned piglets' diets.

Cite this article

LI Lanhai, CHEN Liling, YOU Jinming, HE Qin, LU Yafei, GUO Xiaobo, YANG Jin . Effects of Acidifier and Oregano Oil Instead of Colistin Sulfate on Growth Performance, Diarrhea Rate and Caecal Microorganism Number of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2018 , 30(5) : 1864 -1871 . DOI: 10.3969/j.issn.1006-267x.2018.05.029

References

[1] LI D F,NELSSEN J L,REDDY P G,et al.Transient hypersensitivity to soybean meal in the early-weaned pig[J].Journal of Animal Science,1990,68(6):1790-1799.  

[2] TSILOYIANNIS V K,KYRIAKIS S C,VLEMMAS J,et al.The effect of organic acids on the control of porcine post-weaning diarrhoea[J].Research in Veterinary Science,2001,70(3):287-293.  

[3] 刘文辉.复合酸化剂对断奶仔猪生长性能、抗氧化功能及内分泌功能等的影响[D].硕士学位论文.福州:福建农林大学,2013.

[4] 钱仲仓.控释型丁酸的制备及其对早期断奶仔猪肠屏障影响的研究[D].硕士学位论文.杭州:浙江大学,2010.

[5] DENG Z Y,ZHANG J W,WU G Y,et al.Dietary supplementation with polysaccharides from Semen cassiae enhances immunoglobulin production and interleukin gene expression in early-weaned piglets[J].Journal of the Science of Food and Agriculture,2007,87(10):1868-1873.  

[6] GOMES F E,FONTES D O,SALIBA E O S,et al.Ácido fumárico e sua combinaçào com os ácidos butírico ou fórmico em dietas de leitões recém desmamados[J].Arquivo Brasileiro De Medicina Veterinária E Zootecnia,2007,59(5):1270-1277.  

[7] 贺琴,王自蕊,游金明,等.酵母壁多糖对断奶仔猪生长性能和小肠黏膜形态结构的影响[J].动物营养学报,2016,28(11):3536-3541.

[8] SALISBURY J G,NICHOLLS T J,LAMMERDING A M,et al.A risk analysis framework for the long-term management of antibiotic resistance in food-producing animals[J].International Journal of Antimicrobial Agents,2002,20(3):153-164.  

[9] 韩庆功,宋云义,崔艳红,等.牛至油对仔猪生产性能、抗体水平及粪便微生物的影响[J].河南农业科学,2016,45(7):113-117.

[10] HENRY R W,PICKARD D W,HUGHES P E.Citric acid and fumaric acid as food additives for early-weaned piglets[J].Animal Production,1985,40(3):505-509.  

[11] 曹建国,潘正伟,陈正华,等.牛至油在仔猪饲料中的抗菌促生长效果[J].上海畜牧兽医通讯,2004(1):24-25.

[12] GHEISARI A A,HEIDARI M,KERMANSHAHI R K,et al.Effect of dietary supplementation of protected organic acids on ileal microflora and protein digestibility in broiler chickens[C]//Proceedings of the 16th European Symposium on Poultry Nutrition.Strasbourg:[s.n.],2007:519-522.

[13] PARTANEN K,SILJANDER-RASI H,PENTIKÄINEN J,et al.Effects of weaning age and formic acid-based feed additives on pigs from weaning to slaughter[J].Archives of Animal Nutrition,2007,61(5):336-356.  

[14] FALKOWSKI J F,AHERNE F X.Fumaric and citric acid as feed additives in starter pig nutrition[J].Journal of Animal Science,1984,58(4):935-938.  

[15] 杨世红,李美玉,战欣梅.牛至油替代抗生素对断奶仔猪生产性能及抗病力的影响[J].山东畜牧兽医,2009,30(7):5-6.

[16] WANG H F,GAO K,WANG C,et al.Effects of feeding bamboo vinegar and acidifier as an antibiotic substitute on the growth performance and intestinal bacterial communities of weaned piglets[J].Acta Agriculturae Scandinavica,Section A:Animal Science,2013,63(3):143-150.  

[17] CRANWELL P D,DE NOAKES E,HILL K J.Gastric secretion and fermentation in the suckling pig[J].British Journal of Nutrition,1976,36(1):71.

[18] HAHN T W,LOHAKARE J D,LEE S L,et al.Effects of supplementation of β-glucans on growth performance, nutrient digestibility, and immunity in weanling pigs[J].Journal of Animal Science,2006,84(6):1422-1428.  

[19] 张旭晖,王恬,冀凤杰,等.有机酸化剂对断奶仔猪生长性能和肠道健康的影响[J].动物营养学报,2012,24(3):507-514.

[20] 黄国清,付水广.用牛至油替代抗生素对仔猪生产性能的影响[J].粮食与饲料工业,2006(10):35-36.

[21] GIANNENAS I A.Organic acids in pig and poultry nutrition[J].Feed Additives,2006,57(1):51-62.

[22] 卢娜.日粮中添加不同酸化剂对断奶仔猪的应用研究[D].硕士学位论文.乌鲁木齐:新疆农业大学,2008.

[23] 孔祥杰,姜海龙,蔡维北,等.黄芪茎叶对断奶仔猪盲肠微生物区系的影响[J].中国畜牧杂志,2017,53(3):117-120,124.

[24] 郑兰,李亚雄.抗生素及其替代物在畜禽肠道内的作用及其对肠道微生物和形态结构的影响[J].国外畜牧学(猪与禽),2017,37(1):50-55.

[25] 许丛丛,陈小连,朱丽慧,等.复合抗氧化剂对早期断奶仔猪肠道主要菌群的影响[J].饲料研究,2012(4):4-7.

[26] WANG H F,WANG J L,WANG C,et al.Effect of bamboo vinegar as an antibiotic alternative on growth performance and fecal bacterial communities of weaned piglets[J].Livestock Science,2012,144(1/2):173-180.

[27] BLOMBERG L,HENRIKSSON A,CONWAY P L.Inhibition of adhesion of Escherichia coli K88 to piglet ileal mucus by Lactobacillus spp.[J].Applied and Environmental Microbiology,1993,59(1):34-39.

[28] 晏家友,贾刚,王康宁,等.缓释复合酸化剂对断奶仔猪消化道酸度及肠道功能的影响[J].畜牧兽医学报,2009,40(12):1747-1754.

[29] 廖三赛,袁海春.晶绿福(牛至油)与抗生素对仔猪生产性能的影响[J].养殖与饲料,2003(7):6-7.

[30] 陈会良,袁向阳,黄磊,等.牛至油对仔猪肠道微生物菌群的影响[J].中兽医医药杂志,2005,24(6):32-33.

[31] 邱楚武.牛至油在仔猪饲料中的应用试验[J].粮食与饲料工业,2003(7):32.
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