Molecular Nutrition

Effects of Chitosan on Serum Lipid and Adipocytokine Contents of Laying Breeders

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  • 1. The Key Laboratory of Animal Nutrition and Feed Science of The Inner Mongolia Autonomous Region, College of Animal Sciences, Inner Mongolia Agricultural University, Hohhot 010018, China;
    2. Chifeng Academy of Agricultural and Animal Husbandry Sciences, Chifeng 024031, China

Received date: 2017-11-07

  Online published: 2018-06-20

Abstract

This experiment was conducted to investigate the effects of chitosan with different supplemental levels on serum lipid and adipocytokine contents of laying breeders. Four hundred and fifty 26-week-old Hy-Line brown laying breeders were randomly assigned to 5 groups with 6 replicates in each group and each replicate contained 15 chickens. Chickens in 5 groups were fed experimental diets containing 0 (control), 250, 500, 1 000 and 2 000 mg/kg chitosan, respectively. The trial lasted for 56 days. The results showed as follows:compared with control group, diets supplemented with 250, 500, 1 000 and 2 000 mg/kg chitosan could reduce the contents of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), free fatty acids (FFA) in serum and the content of FFA in liver of laying breeders in different degrees on the days 28 and 56 of the experiment. On the day 28 of experiment, compared with control group, diets supplemented with 250, 500 and 1 000 mg/kg chitosan could significantly reduce the serum triglyceride (TG) content (P ≤ 0.05), supplemented with 500 mg/kg chitosan could significantly reduce the serum very low density lipoprotein (VLDL) content (P ≤ 0.05), supplemented with 250, 500, 1 000 and 2 000 mg/kg chitosan could significantly reduce the serum leptin (LEP) content (P ≤ 0.05), and supplemented with 500 mg/kg chitosan could significantly increase the serum high density lipoprotein cholesterol (HDL-C) content (P ≤ 0.05). On the days 28 and 56 of experiment, the serum TC content of laying breeders showed a significant linear decreasing relationship with the chitosan supplemental level (P<0.01). On the day 28 of experiment, the serum TG (P<0.01), HDL-C (P<0.01), FFA (P=0.04) and VLDL contents (P<0.01) showed a significant quadratic curve relationship with chitosan supplemental level, and when chitosan supplemental level was 652.56 to 967.18 mg/kg, it could better regulate the above indexes. It is concluded that the supplementation of chitosan can improve the healthy level of lipid metabolism in laying breeders, and the effects of chitosan on the contents of lipids in serum and the content of FFA in liver are related to its supplemental level.

Cite this article

LIU Zhiyou, LI Yinhao, YAN Sumei, SHI Binlin, ZHAO Qilong, ZHANG Pengfei . Effects of Chitosan on Serum Lipid and Adipocytokine Contents of Laying Breeders[J]. Chinese Journal of Animal Nutrition, 2018 , 30(6) : 2310 -2317 . DOI: 10.3969/j.issn.1006-267x.2018.06.035

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