Effects of Resveratrol and Sanguinarine on Growth Performance, Serum Indexes and Diarrhea Status of Calves under 2 Months of Age

ZHANG Weibing, ZHANG Rong, BI Yanliang, TU Yan, DU Hanchang, TIAN Zhonghong, DIAO Qiyu

doi:10.3969/j.issn.1006-267x.2018.06.047

2018 , Vol. 30 >Issue 6: 2411 - 2420

DOI: https://doi.org/10.3969/j.issn.1006-267x.2018.06.047

Molecular Nutrition

Effects of Resveratrol and Sanguinarine on Growth Performance, Serum Indexes and Diarrhea Status of Calves under 2 Months of Age

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1. Key Laboratory of Feed Biotechnology of the Ministry of Agriculture, Beijing Key Laboratory for Dairy Cow Nutrition, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China;
2. Shandong Agricultural Biological Immune Technology Engineering Laboratory, Shandong Yinxiang Weiye Group Co., Ltd., Heze 274500, China

Received date: 2017-11-22

Online published: 2018-06-20

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Abstract

This study investigated the effects of resveratrol (RES) and sanguinarine (SAG) on growth performance, serum indexes and diarrhea of Holstein calves under 2 months of age. Fifty-four female 5-day-old Holstein calves were randomly assigned to three treatments with 18 calves per treatment using a completely randomized design. Calves in different treatments were fed a milk replacer (MR), MR supplemented with 0.05 mg/kg BW SAG, and MR supplemented with 4 mg/kg BW RES, respectively. The trial lasted for 55 d. Body weight and body size of calves were measured at 5, 14, 28, 42 and 56 days of age. Diarrhea status of calves was recorded everyday. The blood was collected to determine serum indexes at 60 days of age. The results showed as follow:1) RES and SAG had no significant effects on total weight gain and dry matter intake (DMI) (P>0.05), days of age had significant effects on body weight (P<0.000 1), but there was no interactions between days of age and treatment (P=0.853 9); 2) about body size, the increases of heart girth and hip height of SAG and RES treatments were significantly higher than those of MR treatment (P<0.05); 3) there was no significant difference in diarrhea rate among treatments (P>0.05); 4) RES treatment had significantly higher serum growth hormone, epidermal growth factor and insulin-like growth factor Ⅰ concentrations compared with the other two treatments (P<0.05); 5) serum malondialdehyde concentration in SAG treatment was significantly higher than that in the other two treatments (P<0.05). In summary, the addition of RES or SAG in MR can increase body size of calves under 2 months of age; the addition of RES in MR can increase serum concentrations of GH, EGF and IGF-Ⅰ of calves; RES and SAG have potential as growth promoters for calves.

Key words： calf; plant extracts; resveratrol; sanguinarine; calf breeding

Cite this article

ZHANG Weibing, ZHANG Rong, BI Yanliang, TU Yan, DU Hanchang, TIAN Zhonghong, DIAO Qiyu . Effects of Resveratrol and Sanguinarine on Growth Performance, Serum Indexes and Diarrhea Status of Calves under 2 Months of Age[J]. Chinese Journal of Animal Nutrition, 2018 , 30(6) : 2411 -2420 . DOI: 10.3969/j.issn.1006-267x.2018.06.047

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