This experiment was conducted to study the effects of dietary metabolizable energy and crude protein levels on growth performance and serum biochemical indexes of Taihang chickens during growing period, and to determine the optimum dietary metabolizable energy and crude protein levels, so as to provide basis for formulating feeding standard of Taihang chickens. The metabolic energy (11.0, 11.5 and 12.0 MJ/kg) and crude protein (14%, 15% and 16%) were used as the factors, and the experiment designed with 2 factors and 3 levels. A total of 360 healthy 77-day-old Taihang chickens with similar body weight were selected and randomly divided into 9 groups with 4 replicates per group and 10 chickens per replicate. The pre feeding period was 3 days, and the test period was 42 days. The results showed as follows:1) dietary metabolizable energy level had significant effects on the average daily feed intake and feed to gain ratio of Taihang chickens during growing period (P<0.05), with dietary metabolizable energy level increasing, the average daily feed intake and feed to gain ratio of Taihang chickens during growing period were decreased. Dietary crude protein level had significant effects on the feed to weight ratio of Taihang chickens during growing period (P<0.05), with dietary crude protein level increasing, the average daily feed intake firstly increased and then decreased, and the feed to gain ratio firstly decreased and then increased. Dietary metabolizable energy and crude protein levels showed significant interaction effects on average daily feed intake, average daily gain and of feed to gain ratio of Taihang chickens during growing period (P<0.05). 2) Dietary metabolizable energy level had significant effects on the average daily metabolizable energy intake (ADMEI) and average daily crude protein intake (ADCPI) of Taihang chickens during growing period (P<0.05), with dietary metabolizable energy level increasing, the ADMEI of Taihang chickens during growing period was increased. Dietary crude protein level had significant effects on the ADCPI of Taihang chickens during growing period (P<0.05), with dietary crude protein level increasing, the ADCPI of Taihang chickens during growing period was increased. Dietary metabolizable energy and crude protein levels showed significant interaction effects on ADMEI and ADCPI of Taihang chickens during growing period (P<0.05). 3) Dietary metabolizable energy level had significant effects on serum triglyceride content of Taihang chickens during growing period (P<0.05). Dietary metabolizable energy and crude protein levels showed significant interaction effects on serum triglyceride content of Taihang chickens during growing period (P<0.05). Comprehensive the serum biochemical indexes, dietary metabolizable energy level was 11.5 MJ/kg, it can meet the energy requirement of Taihang chickens. In conclusion, considering all the indexes, the optimum dietary metabolizable energy level of Taihang chickens during growing period is 11.5 MJ/kg, and the optimum dietary crude protein level is 14% to 15%.