Effects of Different Zinc Sources on Growth Performance, Serum Hormone and Immune Indices of Newborn Calves

HAO Liyuan, MA Fengtao, WEI Jingya, SUN Peng, ZHANG Kaizhan

doi:10.3969/j.issn.1006-267x.2018.08.019

Chinese Journal of Animal Nutrition >

2018 , Vol. 30 >Issue 8: 3026 - 3032

DOI: https://doi.org/10.3969/j.issn.1006-267x.2018.08.019

Molecular Nutrition

Effects of Different Zinc Sources on Growth Performance, Serum Hormone and Immune Indices of Newborn Calves

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1. State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
2. Beijing Sino Farm Co., Ltd., Beijing 100028, China

Received date: 2018-01-18

Online published: 2018-08-18

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Abstract

The objective of this trial was to investigate the effects of different zinc sources on growth performance, serum hormone and immune indices of newborn calves. Thirty-six newborn Holstein dairy female calves were randomly assigned to 3 groups with 12 calves per group. Calves in control group were no addition, and others in experimental groups were added 457 mg zinc methionine and 104 mg zinc oxide (equivalent to 80 mg zinc) per calf every day, respectively. Zinc methionine and zinc oxide were mixed with milk and fed directly to the calves. The whole experiment lasted for 14 days. Starter diet was supplemented to all calves on the fourth day after birth. Incidents of diarrhea and feed intake of individual calf were recorded every day. Calves were measured for body height, body slant length, bust and weight after birth and before feeding on the morning of 15 days of age. Meanwhile, blood samples were taken from all the calves before feeding on the morning of 15 days of age, and the contents of immunoglobulin and hormone in the serum were measured. The results showed as follows:1) compared with the control group, dietary supplementation of zinc methionine significantly increased the average daily gain of calves (P<0.05), significantly decreased the diarrhea rate of calves (P<0.05). Different zinc sources did not significantly influence the average daily feed intake, total body height gain, total body slant gain and total bust gain of calves (P>0.05). 2) Compared with the control group, dietary supplementation of zinc methionine and zinc oxide significantly decreased the serum insulin content of calves (P<0.05). 3) Compared with the control group, dietary supplementation of zinc oxide significantly increased the contents of immunoglobulin G and immunoglobulin M in serum of calves (P<0.05). And no significant difference was observed in serum immunoglobulin A content of calves among all groups (P>0.05). In summary, supplementation of zinc methionine to newborn calves effectively promotes calf growth, and reduces the diarrhea rate, while supplementation of zinc oxide helps to improve the immune function of calves.

Key words： newborn calves; zinc methionine; zinc oxide; growth performance; diarrhea; serum hormone; immune function

Cite this article

HAO Liyuan, MA Fengtao, WEI Jingya, SUN Peng, ZHANG Kaizhan . Effects of Different Zinc Sources on Growth Performance, Serum Hormone and Immune Indices of Newborn Calves[J]. Chinese Journal of Animal Nutrition, 2018 , 30(8) : 3026 -3032 . DOI: 10.3969/j.issn.1006-267x.2018.08.019

References

[1] BONAVENTURA P,BENEDETTI G,ALBARÈDE F,et al.Zinc and its role in immunity and inflammation[J].Autoimmunity Reviews,2015,14(4):277-285.

[2] SUTTLE N F.Mineral nutrition of livestock[M].4th ed.Wallingford:CABI Publishing,2010:426-458.

[3] SHEN J H,CHEN Y,WANG Z S,et al.Coated zinc oxide improves intestinal immunity function and regulates microbiota composition in weaned piglets[J].British Journal of Nutrition,2014,111(12):2123-2134.

[4] MILLER H M,TOPLIS P,SLADE R D.Can outdoor rearing and increased weaning age compensate for the removal of in-feed antibiotic growth promoters and zinc oxide[J].Livestock Science,2009,125(2/3):121-131.

[5] LIBERATO S C,SINGH G,MULHOLLAND K.Zinc supplementation in young children:a review of the literature focusing on diarrhoea prevention and treatment[J].Clinical Nutrition,2015,34(2):181-188.

[6] PRASAD A S.Zinc:an antioxidant and anti-inflammatory agent:role of zinc in degenerative disorders of aging[J].Journal of Trace Elements in Medicine and Biology,2014,28(4):364-371.

[7] NRC.Nutrient requirements of dairy cattle[S].7th ed.Washington,D.C.:National Academies Press,2001.

[8] GLOVER A D,PUSCHNER B,ROSSOW H A,et al.A double-blind block randomized clinical trial on the effect of zinc as a treatment for diarrhea in neonatal Holstein calves under natural challenge conditions[J].Preventive Veterinary Medicine,2013,112(3/4):338-347.

[9] VAN SOEST P J,ROBERTSON J,LEWIS B.Symposium:carbohydrate methodology,metabolism,and nutritional implications in dairy cattle:methods for dietary fiber,neutral detergent fiber,and nonstarch polysaccharides in relation to animal nutrition[J].Journal of Dairy Science,1991,74(10):3583-3597.

[10] TEIXEIRA A G V,STEPHENS L,DIVERS T J,et al.Effect of crofelemer extract on severity and consistency of experimentally induced enterotoxigenic Escherichia coli diarrhea in newborn Holstein calves[J].Journal of Dairy Science,2015,98(11):8035-8043.

[11] 周怿,刁其玉,屠焰,等.酵母β-葡聚糖和杆菌肽锌对早期断奶犊牛生长性能和胃肠道发育的影响[J].动物营养学报,2011,23(5):813-820.

[12] 蔡秋,张明忠,刘康书,等.饲粮添加铜、铁和锌对牛组织和血液铅和镉含量的影响[J].动物营养学报,2012,24(3):571-576.

[13] 彭秋媛,黄大鹏.维生素A及蛋氨酸锌水平对断奶仔猪生长性能及部分血清抗氧化指标的影响[J].中国畜牧兽医,2016,43(6):1500-1505.

[14] 孙玲.微生态制剂和蛋氨酸锌及其互作效应对蛋鸡生产性能、蛋品质和抗氧化性能的影响[D].硕士学位论文.长春:沈阳农业大学,2017.

[15] 白彦.不同锌源及水平对商品肉兔生长性能及组织锌沉积的影响[D].硕士学位论文.杨凌:西北农林科技大学,2010.

[16] 刘翠艳,淡秀荣,左龙.蛋氨酸锌在反刍动物生产中的应用[J].中国牛业科学,2014,40(5):41-43.

[17] 师周戈,白元生.注射微量元素对犊牛健康的影响[J].当代畜牧,2014(30):45-46.

[18] 雷东风.不同形式和水平的锌、铜对仔猪的影响[D].硕士学位论文.郑州:河南农业大学,2010.

[19] 陈娜娜,马莲香,侯川川,等.蛋氨酸锌对蛋鸡生产性能、肠道形态、组织学结构及盲肠微生物菌群的影响[J].中国畜牧杂志,2017,53(9):102-108.

[20] HU C H,SONG J,YOU Z T,et al.Zinc Oxide-Montmorillonite hybrid influences diarrhea,intestinal mucosal integrity and digestive enzyme activity in weaned pigs[J].Biological Trace Element Research,2012,149(2):190-196.

[21] 王竹.锌和胰岛素、糖尿病的关系[J].国外医学(卫生学分册),1999(6):343-347.

[22] 刘信艳,吴蕴棠,孙忠,等.锌对高糖高脂饲料喂养大鼠胰岛素敏感性影响[J].中国公共卫生,2013,29(5):691-693.

[23] 范炜,殷红,李春风,等.胰岛素样生长因子1调节生长发育的研究进展[J].黑龙江畜牧兽医,2013(1):19-22.

[24] O'NEILL B T,LAURITZEN H P M M,HIRSHMAN M F,et al.Differential role of insulin/IGF-1 receptor signaling on muscle growth and glucose homeostasis[J].Cell Reports,2015,11(8):1220-1235.

[25] LI X L,YIN J D,LI D F,et al.Dietary supplementation with zinc oxide increases IGF-1 and IGF-1 receptor gene expression in the small intestine of weanling piglets[J].The Journal of Nutrition,2006,136(7):1786-1791.

[26] FRANZ J,MILON A,SALMON H.Synthesis of immunoglobulins IgG,IgM and IgA during the ontogeny of foetal pigs[J].Acta Veterinaria Brno,1982,51(1/2/3/4):23-30.

[27] 吕广宙,陆治年,丁晓明.低锌日粮补锌对断奶前后犊牛免疫机能的影响[J].畜牧兽医学报,1995,26(3):207-213.

[28] NAGALAKSHMI D,SRIDHAR K,SATYANARAYANA M,et al.Effect of replacing inorganic zinc with a lower level of organic zinc (zinc propionate) on performance,biochemical constituents,antioxidant,immune and mineral status in buffalo calves[J].Indian Journal of Animal Research,2017,doi:10.18805/ijar.B-3362.

[29] 许甲平,鲍宏云,冯一凡.蛋氨酸锌对产蛋鸡产蛋性能和非特异性免疫功能的影响[J].饲料工业,2012,33(20):58-61.

[30] WANG C,XIE P,LIU L L,et al.Use of lower level of capsulated zinc oxide as an alternative to pharmacological dose of zinc oxide for weaned piglets[J].Asian Journal of Animal and Veterinary Advances,2012,7(12):1290-1300.

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