Effects of Chlorogenic Acid Supplementation in High-Fat Diets on Growth Performance and Lipid Metabolism of Grass Carp(Ctenopharyngodon idellus)

YANG Tianjun, CHEN Yanliang, LIU Wenshu, GUO Xiaoze, TANG Yanqiang, LIU Yuting, LI Debing, LI Siming

doi:10.3969/j.issn.1006-267x.2018.08.041

2018 , Vol. 30 >Issue 8: 3219 - 3228

DOI: https://doi.org/10.3969/j.issn.1006-267x.2018.08.041

Molecular Nutrition

Effects of Chlorogenic Acid Supplementation in High-Fat Diets on Growth Performance and Lipid Metabolism of Grass Carp(Ctenopharyngodon idellus)

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1. Jiangxi Academy of Agricultural Science, Nanchang 330200, China;
2. College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China

Received date: 2018-01-26

Online published: 2018-08-18

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Abstract

This study aimed to investigate the effects of chlorogenic acid (CGA) supplementation in high-fat diets on growth performance, lipid metabolism of grass carp(Ctenopharyngodon idellus). A total of 360 healthy and grass carp with an initial body weight (7.53±0.30) g were randomly divided into 4 groups with 3 replicates per group and 30 craps per replicate. Craps in C (control), 200CGA, 400CGA and 600CGA groups were fed high-fat diet (crude lipid was about 9.00%) supplemented with 0, 200, 400 and 600 mg/kg CGA for 11 weeks, respectively. The results showed that compared with C group:1) 400CGA group had significantly higher final body weight (FBW), weight gain rate (WGR) and protein efficiency ratio (PER) of diet (P<0.05), FBW increased by 15.90%, WGR increased by 22.96%m and PER increased by 17.75%, 400CGA group had significantly lower feed coefficient (P<0.05), which was decreased by 14.86%. 2) 200CGA and 400CGA groups had significantly lower serum contents of total cholesterol (T-CHO) and low density lipoprotein cholesterol (LDL-C) (P<0.05), experimental groups had significantly higher serum content of high density lipoprotein cholesterol (HDL-C) (P<0.05). 3) Experimental groups had significantly lower contents of triglyceride (TG), T-CHO and LDL-C in hepatopancreas (P<0.05), and significantly higher activities of lipase(HL) and total lipase(TL) in hepatopancreas (P<0.05); 400CGA and 600CGA groups had significantly higher HDL-C content in hepatopancreas (P<0.05); 400CGA group had significantly higher lipoprotein lipase (LPL) activity in hepatopancreas (P<0.05). 4) Hepatopancreas sections under transmission electron microscope showed that lipid droplets were smaller, littleness and scattered in 400CGA and 600CGA groups. As a result, the supplementation of 400 mg/kg CGA in high-fat diets can promote lipid metabolism and growth performance of grass carp.

Key words： grass carp; chlorogenic acid; high-fat diet; growth performance; lipid metabolism

Cite this article

YANG Tianjun, CHEN Yanliang, LIU Wenshu, GUO Xiaoze, TANG Yanqiang, LIU Yuting, LI Debing, LI Siming . Effects of Chlorogenic Acid Supplementation in High-Fat Diets on Growth Performance and Lipid Metabolism of Grass Carp(Ctenopharyngodon idellus)[J]. Chinese Journal of Animal Nutrition, 2018 , 30(8) : 3219 -3228 . DOI: 10.3969/j.issn.1006-267x.2018.08.041

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