Developmental Changes on Related Gene and Protein Expression of Adiponectin of Shaziling Pigs

CHEN Yuguang, QIN Longshan, HE Xi

doi:10.3969/j.issn.1006-267x.2018.10.049

Chinese Journal of Animal Nutrition >

2018 , Vol. 30 >Issue 10: 4229 - 4236

DOI: https://doi.org/10.3969/j.issn.1006-267x.2018.10.049

Molecular Nutrition

Developmental Changes on Related Gene and Protein Expression of Adiponectin of Shaziling Pigs

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College of Animal Science and Technology, Hunan Agricultural University;Hunan Livestock Safety Production Cooperative Innovation Center, Changsha 410001, China

Received date: 2018-04-06

Online published: 2018-10-20

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Abstract

The experiment was conducted to research the developmental changes of mRNA and protein expression of adiponectin (ADIPOQ), adiponectin receptors (ADIPOR) and related gene in Shaziling pigs. The developmental changes on mRNA and protein expression of ADIPOQ, ADIPOR1, ADIPOR2, topoisomerase 2β (TOP2β) and TATA binding protein (TBP) of different tissues and organs were measured in 12 Shaziling pigs (1, 28 and 140 days of age, 4 head per age). The results showed that the mRNA expressions of ADIPOQ, ADIPOR1, ADIPOR2, TOP2β and TBP in different tissues and organs of pigs were tend to increase with the growth of pigs, the mRNA expressions of the above genes in most tissues and organs on 140 day of age were significantly higher than those on 1 day of age (P<0.05 or P<0.01). The protein expressions of ADIPOD, ADIPOR1 and ADIPOR2 in most tissue and organ showed a decreased trend. The results showed that the mRNA expressions of related gene and proteins of ADIPOQ are negatively correlation with the fat deposition of pigs, and the body can adjust according to its own needs.

Key words： adiponectin; adiponectin receptor; gene; developmental change; Shaziling pigs

Cite this article

CHEN Yuguang, QIN Longshan, HE Xi . Developmental Changes on Related Gene and Protein Expression of Adiponectin of Shaziling Pigs[J]. Chinese Journal of Animal Nutrition, 2018 , 30(10) : 4229 -4236 . DOI: 10.3969/j.issn.1006-267x.2018.10.049

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