Effects of Pasteurized &beta;-Lactam Antibiotic Milk on Growth and Development of Gastrointestinal Tract of Calves

XIN Xiaoyue, QU Yongli, YUAN Xue, GAO Yan, WANG Lu, YIN Shuxin, ZHANG Shuai

doi:10.3969/j.issn.1006-267x.2018.10.052

Chinese Journal of Animal Nutrition >

2018 , Vol. 30 >Issue 10: 4251 - 4261

DOI: https://doi.org/10.3969/j.issn.1006-267x.2018.10.052

Molecular Nutrition

Effects of Pasteurized β-Lactam Antibiotic Milk on Growth and Development of Gastrointestinal Tract of Calves

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College of Animal Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China

Received date: 2018-04-07

Online published: 2018-10-20

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Abstract

This study was performed to investigate the effects of feeding pasteurized β-lactam antibiotic milk on growth and development of gastrointestinal tract of calves. Eighteen 3-day-old healthy Holstein male calves with an similar body weight were randomly divided into 2 groups. Calves in control group were fed β-lactam antibiotic milk, and those in experimental group were fed pasteurized β-lactam antibiotic milk. The pasteurization condition was as follows:milk was heated at 63 to 65℃ for 30 min. Calves were weaned at 60 days of age, and the experiment period was 180 days. The results showed as follows:1) compared with β-lactam antibiotic milk, the counts of total bacteria, Escherichia coli and Salmonella in pasteurized β-lactam antibiotic milk were significantly decreased (P<0.01); 2) compared with the control group, average daily gain of calves during 3 to 60 days of age of experimental group was significantly higher (P<0.05), fecal score and diarrhea rate of calves during 3 to 10 days of age and 3 to 60 days of age of experimental group were significantly lower (P<0.05); 3) there was no significant difference in the papilla height, papilla width and mucosal thickness of dorsal sac of the rumen and ventral sac of the rumen between experimental group and control group at 60, 90 and 180 days of age (P>0.05); compared with the control group, the duodenum villous height and villous height/crypt depth of experimental group at 60 days of age were significantly increased (P<0.05), the duodenum crypt depth of experimental group at 90 days of age was significantly decreased (P<0.05), the jejunum villous width at 90 days of age, the jejunum villous height/crypt depth at 90 and 180 days of age were significantly higher (P<0.05), the jejunum crypt depth was significantly decreased at 60, 90 and 180 days of age (P<0.05); there was no significant difference in the ileum histomorphology between 2 groups at each time point (P>0.05). The results prove that feeding pasteurized β-lactam antibiotic milk can improve growth and development of lactating calves, and can promote calves' gastrointestinal development, mainly in promoting development of small intestine morphology.

Key words： calves; antibiotic milk; pasteurisation; growth; gastrointestinal tract development

Cite this article

XIN Xiaoyue, QU Yongli, YUAN Xue, GAO Yan, WANG Lu, YIN Shuxin, ZHANG Shuai . Effects of Pasteurized β-Lactam Antibiotic Milk on Growth and Development of Gastrointestinal Tract of Calves[J]. Chinese Journal of Animal Nutrition, 2018 , 30(10) : 4251 -4261 . DOI: 10.3969/j.issn.1006-267x.2018.10.052

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