Molecular Nutrition

Research Progress of Aryl Hydrocarbon Receptor in Regulating Intestinal Inflammation

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  • 1. College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China;
    2. Feed Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Feed Biotechnology of Ministry of Agriculture, Beijing 100081, China

Received date: 2018-05-07

  Online published: 2018-12-19

Abstract

The aryl hydrocarbon receptor (AhR) is a transcription factor activated by synthetic ligands, and has important role on environmental toxins, organism metabolism and immunomodulatory. It has recently reported that AhR is a key factor in immune regulation, AhR regulating the inflammatory bowel disease (IBD) has become hot topic in current research. This article reviews the latest research on structure, ligand and signal transduction pathway of AhR and AhR regulating the intestinal inflammation, and provide new ideas for cure the IBD.

Cite this article

LI Chengliang, QI Guanghai, PENG Peng, FANG Rejun . Research Progress of Aryl Hydrocarbon Receptor in Regulating Intestinal Inflammation[J]. Chinese Journal of Animal Nutrition, 2018 , 30(12) : 4776 -4785 . DOI: 10.3969/j.issn.1006-267x.2018.12.002

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