Molecular Nutrition

Advances in Biological Functions of Animal Exosomes

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  • 1. State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agriculture Sciences, Beijing 100193, China;
    2. Beijing Key Laboratory for Dairy Cow Nutrition, Beijing University of Agriculture, Beijing 102206, China

Received date: 2018-05-07

  Online published: 2018-12-19

Abstract

Exosomes, internal proteins, lipids, and nucleic acids coated by phospholipid bilayer membranes, are one type of small extracellular vesicles, which can mediate cell-cell communication. Exosomes are naturally present in many kinds of body fluids, such as blood, urine, saliva, cerebrospinal fluid and milk, which can provide a basis for their extensive regulation of physiological and pathological processes. Currently, exosomes have been extensively studied in human malignant tumor and autoimmune diseases, but the researches on animal physiology and pathology are less. Recent studies have shown that exosomes are abundant in the milk of various mammals and they provide immunological protection for infants through miRNAs. The origin, biological functions and methods of isolation and identification of exosomes were reviewed, hoping to provide reference for its researches on animal husbandry.

Cite this article

QUAN Suyu, NAN Xuemei, JIANG Linshu, XIONG Benhai . Advances in Biological Functions of Animal Exosomes[J]. Chinese Journal of Animal Nutrition, 2018 , 30(12) : 4786 -4791 . DOI: 10.3969/j.issn.1006-267x.2018.12.003

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