Molecular Nutrition

Physiological Functions of Inulin and Its Application in Livestock and Poultry Production

Expand
  • College of Animal Science, Hunan Agricultural University, Changsha 410128, China

Received date: 2018-05-04

  Online published: 2018-12-19

Abstract

Inulin, a type of plant-derived natural fructan, can balance intestinal microorganism, regulate immune and lipid metabolism, and promote mineral absorption and so on. As a natural feed additive, inulin has the advantages of improving livestock's and poultry's intestinal health and immunity, which has a bright application prospect. In this paper, the physicochemical properties, extraction process, main physiological functions of inulin and application in livestock and poultry production were reviewed in order to provide references for the application of inulin in livestock and poultry feed.

Cite this article

CHEN Jiayi, CHEN Fengming, OU Shuqi, ZHAO Yurong . Physiological Functions of Inulin and Its Application in Livestock and Poultry Production[J]. Chinese Journal of Animal Nutrition, 2018 , 30(12) : 4792 -4798 . DOI: 10.3969/j.issn.1006-267x.2018.12.004

References

[1] PETKOVA N T,OGNYANOV M,TODOROVA M,et al.Ultrasound-assisted extraction and characterisation of inulin-type fructan from roots of elecampane (Inula helenium L.)[J].Acta Scientifica Naturalis,2015,1(2):225-235.



[2] HU Y X,ZHANG J,YU C W,et al.Synthesis,characterization,and antioxidant properties of novel inulin derivatives with amino-pyridine group[J].International Journal of Biological Macromolecules,2014,70:44-49.



[3] SHOAIB M,SHEHZAD A,OMAR M,et al.Inulin:properties,health benefits and food applications[J].Carbohydrate Polymers,2016,147:444-454.



[4] VASSILEV D,PETKOVA N,KOLEVA M,et al.Ultrasound-assisted synthesis of sucrose and fructooligosaccharides esters as bio-plasticizers[J].Journal of Renewable Materials,2016,4(1):24-30.  



[5] LIU J,LU J F,WEN X Y,et al.Antioxidant and protective effect of inulin and catechin grafted inulin against CCl4-induced liver injury[J].International Journal of Biological Macromolecules,2015,72:1479-1484.



[6] MUDANNAYAKE D C,WIMALASIRI K M S,SILVA K F S T,et al.Comparison of properties of new sources of partially purified inulin to those of commercially pure chicory inulin[J].Journal of Food Science,2015,80(5):C950-C960.



[7] FLAMM G,GLINSMANN W,KRITCHEVSKY D,et al.Inulin and oligofructose as dietary fiber:a review of the evidence[J].Critical Reviews in Food Science and Nutrition,2001,41(5):353-362.  



[8] DE OLIVEIRA A J B,GONÇALVES R A C,CHIERRITO T P,et al.Structure and degree of polymerisation of fructooligosaccharides present in roots and leaves of Stevia rebaudiana (Bert.) Bertoni[J].Food Chemistry,2011,129(2):305-311.  



[9] RONKART S N,BLECKER C,FOURMANOIR H,et al.Isolation and identification of inulooligosaccharides resulting from inulin hydrolysis[J].Analytica Chimica Acta,2007,604(1):81-87.  



[10] VALLURU R,VAN DER ENDE W.Plant fructans in stress environments:emerging concepts and future prospects[J].Journal of Experimental Botany,2008,59(11):2905-2916.  



[11] KAUR N,GUPTA A K.Applications of inulin and oligofructose in health and nutrition.[J].Journal of Biosciences,2002,27(7):703-714.  



[12] FRANCK A.Technological functionality of inulin and oligofructose[J].British Journal of Nutrition,2002,87(Suppl.2):S287-S291.



[13] WADA T,SUGATANI J,TERADA E,et al.Physicochemical characterization and biological effects of inulin enzymatically synthesized from sucrose[J].Journal of Agricultural and Food Chemistry,2005,53(4):1246-1253.  



[14] LI S Z,CHAN-HALBRENDT C.Ethanol production in (the) People's republic of China:potential and technologies[J].Applied Energy,2009,86(Suppl.1):S162-S169.



[15] PANCHEV I,DELCHEV N,KOVACHEVA D,et al.Physicochemical characteristics of inulins obtained from Jerusalem artichoke (Helianthus tuberosus L.)[J].European Food Research and Technology,2011,233(5):889-896.  



[16] COUSSEMENT P A A.Inulin and oligofructose:safe intakes and legal status[J].The Journal of Nutrition,1999,129(7):1412S-1417S.



[17] 肖仔君,朱定和,王小红,等.菊芋中菊粉提取工艺的研究[J].现代食品科技,2013(2):315-318.



[18] MILANI E,KOOCHEKI A,GOLIMOVAHHED Q A.Extraction of inulin from burdock root (Arctium lappa) using high intensity ultrasound[J].International Journal of Food Science & Technology,2011,46(8):1699-1704.  



[19] LI B,MENG X J,SUN L W.Isolation,chemical characterization and in vitro antioxidant activities of polysaccharides from Aconitum coreanum[J].Journal of Medicinal Plants Research,2012(7):1353-1360.



[20] SAMANTA A K,SENANI S,KOLTE A P,et al.Effect of prebiotic on digestibility of total mixed ration[J].The Indian Veterinary Journal,2012,89(1):41-42.



[21] TARINI J,WOLEVER T M S.The fermentable fibre inulin increases postprandial serum short-chain fatty acids and reduces free-fatty acids and ghrelin in healthy subjects[J].Applied Physiology,Nutrition,and Metabolism,2010,35(1):9-16.  



[22] RÍOS-COVIÁN D,RUAS-MADIEDO P,MARGOLLES A,et al.Intestinal short chain fatty acids and their link with diet and human health[J].Frontiers in Microbiology,2016,7:185.



[23] REBOLÉ A,ORTIZ L T,RODRÍGUEZ M L,et al.Effects of inulin and enzyme complex,individually or in combination,on growth performance,intestinal microflora,cecal fermentation characteristics,and jejunal histomorphology in broiler chickens fed a wheat-and barley-based diet[J].Poultry Science,2010,89(2):276-286.  



[24] ZHU L M,QIN S,ZHAI S X,et al.Inulin with different degrees of polymerization modulates composition of intestinal microbiota in mice[J].FEMS Microbiology Letters,2017,364(10):doi:10.1093/femsle/fnx075.



[25] VAN DE WIELE T,BOON N,POSSEMIERS S,et al.Inulin-type fructans of longer degree of polymerization exert more pronounced in vitro prebiotic effects[J].Journal of Applied Microbiology,2007,102(2):452-460.



[26] PATTERSON J K,YASUDA K,WELCH R M,et al.Supplemental dietary inulin of variable chain lengths alters intestinal bacterial populations in young pigs[J].The Journal of Nutrition,2010,140(12):2158-2161.  



[27] ARCIA P L,COSTELL E,TÁRREGA A,et al.Inulin blend as prebiotic and fat replacer in dairy desserts:optimization by response surface methodology[J].Journal of Dairy Science,2011,94(5):2192-2200.  



[28] VOGT L,RAMASAMY U,MEYER D,et al.Immune modulation by different types of β2→1-fructans is Toll-like receptor dependent[J].PLoS One,2013,8(7):e68367.



[29] ORTEGA-GONZÁLEZ M,OCÓN B,ROMERO-CALVO I,et al.Nondigestible oligosaccharides exert nonprebiotic effects on intestinal epithelial cells enhancing the immune response via activation of TLR4-NFκB[J].Molecular Nutrition & Food Research,2014,58(2):384-393.  



[30] CAPITÁN-CAÑADAS F,ORTEGA-GONZÁLEZ M,GUADIX E M,et al.Prebiotic oligosaccharides directly modulate proinflammatory cytokine production in monocytes via activation of TLR4[J].Molecular Nutrition & Food Research,2014,58(5):1098-1110.  



[31] HUANG Q Q,WEI Y N,LV Y J,et al.Effect of dietary inulin supplements on growth performance and intestinal immunological parameters of broiler chickens[J].Livestock Science,2015,180:172-176.



[32] ROY C C,KIEN C L,BOUTHILLIER L,et al.Short-chain fatty acids:ready for prime time?[J].Nutrition in Clinical Practice,2006,21(6):351-366.



[33] DEN BESTEN G,LANGE K,HAVINGA R,et al.Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids[J].American Journal of Physiology:Gastrointestinal and Liver Physiology,2013,305(12):G900-G910.



[34] RÍOS-COVIÁN D,RUAS-MADIEDO P,MARGOLLES A,et al.Intestinal short chain fatty acids and their link with diet and human health[J].Frontiers in Microbiology,2016,7:185.



[35] DE BESTEN G,VAN EUNEN K,GROEN A K,et al.The role of short-chain fatty acids in the interplay between diet,gut microbiota,and host energy metabolism[J].Journal of Lipid Research,2013,54(9):2325-2340.  



[36] FIORDALISO M,KOK N,DESAGER J P,et al.Dietary oligofructose lowers triglycerides,phospholipids and cholesterol in serum and very low density lipoproteins of rats[J].Lipids,1995,30(2):163-167.  



[37] KOK N,ROBERFROID M,ROBERT A,et al.Involvement of lipogenesis in the lower VLDL secretion induced by oligofructose in rats[J].British Journal of Nutrition,1996,76(6):881-890.  



[38] BEYLOT M.Effects of inulin-type fructans on lipid metabolism in man and in animal models[J].British Journal of Nutrition,2005,93(Suppl.1):S163-S168.



[39] KIM M,SHIN H K.The water-soluble extract of chicory influences serum and liver lipid concentrations,cecal short-chain fatty acid concentrations and fecal lipid excretion in rats[J].The Journal of Nutrition,1998,128(10):1731-1736.  



[40] YUSRIZAL,CHEN T C.Effect of adding chicory fructans in feed on broiler growth performance,serum cholesterol and intestinal length[J].International Journal of Poultry Science,2003,2(3):214-219.  



[41] SANG-OH P,BYUNG-SUNG P.Effect of feeding inulin oligosaccharides on cecum bacteria,egg quality and egg production in laying hens[J].African Journal of Biotechnology,2012,11(39):9516-9521.  



[42] VELASCO S,ORTIZ L T,ALZUETA C,et al.Effect of inulin supplementation and dietary fat source on performance,blood serum metabolites,liver lipids,abdominal fat deposition,and tissue fatty acid composition in broiler chickens[J].Poultry Science,2010,89(8):1651-1662.  



[43] DEWULF E M,CANI P D,NEYRINCK A M,et al.Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARγ-related adipogenesis in the white adipose tissue of high-fat diet-fed mice[J].The Journal of Nutritional Biochemistry,2011,22(8):712-722.  



[44] DELZENNE N M,DAUBIOUL C,NEYRINCK A,et al.Inulin and oligofructose modulate lipid metabolism in animals:review of biochemical events and future prospects[J].British Journal of Nutrition,2002,87(Suppl.2):S255-S259.



[45] CHEN Y C,CHEN T C.Mineral utilization in layers as influenced by dietary oligofructose and inulin[J].International Journal of Poultry Science,2004,3(7):442-445.  



[46] ORTIZ L T,RODRÍGUEZ M L,ALZUETA C,et al.Effect of inulin on growth performance,intestinal tract sizes,mineral retention and tibial bone mineralisation in broiler chickens[J].British Poultry Science,2009,50(3):325-332.  



[47] SCHOLZ-AHRENS K E,SCHREZENMEIR J.Inulin and oligofructose and mineral metabolism:the evidence from animal trials[J].The Journal of Nutrition,2007,137(Suppl.11):2513S-2523S.



[48] ?WIATKIEWICZ S,KORELESKI J,ARCZEWSKA-W?OSEK A.Effect of prebiotic fructans and organic acids on mineral retention in laying hens[J].Acta Agriculturae Scandinavica,Section A:Animal Science,2010,60(2):125-128.  



[49] YASUDA K,DAWSON H D,WASMUTH E V,et al.Supplemental dietary inulin influences expression of iron and inflammation related genes in young pigs[J].The Journal of Nutrition,2009,139(11):2018-2023.  



[50] TAKO E,GLAHN R P,WELCH R M,et al.Dietary inulin affects the expression of intestinal enterocyte iron transporters,receptors and storage protein and alters the microbiota in the pig intestine[J].British Journal of Nutrition,2008,99(3):472-480.



[51] ROBERFROID M B.Functional foods:concepts and application to inulin and oligofructose[J].British Journal of Nutrition,2002,87(Suppl.2):S139-S143.



[52] GRIFFIN I J,DAVILA P M,ABRAMS S A.Non-digestible oligosaccharides and calcium absorption in girls with adequate calcium intakes[J].British Journal of Nutrition,2002,87(Suppl.2):S187-S191.



[53] SAMOLI? SKA W,GRELA E R.Comparative effects of inulin with different polymerization degrees on growth performance,blood trace minerals,and erythrocyte indices in growing-finishing pigs[J].Biological Trace Element Research,2017,176(1):130-142.  



[54] SPENCER J D,TOUCHETTE K J,LIU H,et al.Effect of spray-dried plasma and fructooligosaccharide on nursery performance and small intestinal morphology of weaned pigs[J].Journal of Animal Science,1997,75(Suppl.1):199.



[55] PIERCE K M,SWEENEY T,BROPHY P O,et al.The effect of lactose and inulin on intestinal morphology,selected microbial populations and volatile fatty acid concentrations in the gastro-intestinal tract of the weanling pig[J].Animal Science,2006,82(3):311-318.



[56] HANSEN C F,SØRENSEN G,LYNGBYE M.Reduced diet crude protein level,benzoic acid and inulin reduced ammonia,but failed to influence odour emission from finishing pigs[J].Livestock Science,2007,109(1/2/3):228-231.



[57] PETKEVI? IUS S,KNUDSEN K E B,MURRELL K D,et al.The effect of inulin and sugar beet fibre on Oesophagostomum dentatum infection in pigs[J].Parasitology,2003,127(1):61-68.  



[58] SEVANE N,BIALADE F,VELASCO S,et al.Dietary inulin supplementation modifies significantly the liver transcriptomic profile of broiler chickens[J].PLoS One,2014,9(6):e98942.



[59] SANG-OH P,BYUNG-SUNG P.Effect of dietary microencapsulated-inulin on carcass characteristics and growth performance in broiler chickens[J].Journal of Animal and Veterinary Advances,2011,10(10):1342-1349.  



[60] NABIZADEH A,GEVORKYAN O,GOLIAN A.Effect of inulin on some hematological,immunological parameters and broiler chickens performance[J].Journal of Animal and Veterinary Advances,2012,11(18):3304-3311.  



[61] BIGGS P,PARSONS C M,FAHEY G C.The effects of several oligosaccharides on growth performance,nutrient digestibilities,and cecal microbial populations in young chicks[J].Poultry Science,2007,86(11):2327-2336.  



[62] REHMAN H,HELLWEG P,TARAS D,et al.Effects of dietary inulin on the intestinal short chain fatty acids and microbial ecology in broiler chickens as revealed by denaturing gradient gel electrophoresis[J].Poultry Science,2008,87(4):783-789.  
Outlines

/