[1] QUINTEIRO-FILHO W M,RIBEIRO A,FERRAZ-DE-PAULA V,et al.Heat stress impairs performance parameters,induces intestinal injury,and decreases macrophage activity in broiler chickens[J].Poultry Science,2010,89(9):1905-1914.

[2] VALE W,SPIESS J,RIVIER C,et al.Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin[J].Science,1981,213(4514):1394-1397.

[3] LOVEJOY D A,DE LANNOY L.Evolution and phylogeny of the corticotropin-releasing factor (CRF) family of peptides:expansion and specialization in the vertebrates[J].Journal of Chemical Neuroanatomy,2013,54:50-56.
[4] SOLINAS G,SUMMERMATTER S,MAINIERI D,et al.Corticotropin-releasing hormone directly stimulates thermogenesis in skeletal muscle possibly through substrate cycling between
de novo lipogenesis and lipid oxidation[J].Endocrinology,2006,147(1):31-38.

[5] BACKSTRÖM T,WINBERG S.Central corticotropin releasing factor and social stress[J].Frontiers in Neuroscience,2013,7:117.
[6] NOZU T,TSUCHIYA Y,KUMEI S,et al.Peripheral corticotropin-releasing factor (CRF) induces stimulation of gastric contractions in freely moving conscious rats:role of CRF receptor types 1 and 2[J].Neurogastroenterology & Motility,2013,25(2):190-197.

[7] LIU S,CHANG J,LONG N,et al.Endogenous CRF in rat large intestine mediates motor and secretory responses to stress[J].Neurogastroenterology & Motility,2015,28(2):281-291.
[8] CALLAGHAN B,FURNESS J B.Novel and conventional receptors for ghrelin,desacyl-ghrelin,and pharmacologically related compounds[J].Pharmacological Reviews,2014,66(4):984-1001.

[9] KOJIMA M,HOSODA H,DATE Y,et al.Ghrelin is a growth-hormone-releasing acylated peptide from stomach[J].Nature,1999,402(6762):656-660.

[10] KAIYA H,MIYAZATO M,KANGAWA K,et al.Ghrelin:a multifunctional hormone in non-mammalian vertebrates[J].Comparative Biochemistry and Physiology Part A:Molecular & Integrative Physiology,2008,149(2):109-128.

[11] TINOCO A B,NÄSLUND J,DELGADO M J,et al.Ghrelin increases food intake,swimming activity and growth in juvenile brown trout (
Salmo trutta)[J].Physiology & Behavior,2014,124(2):15-22.
[12] FURUSE M,TACHIBANA T,OHGUSHI A,et al.Intracerebroventricular injection of ghrelin and growth hormone releasing factor inhibits food intake in neonatal chicks[J].Neuroscience Letters,2001,301(2):123-126.

[13] KAIYA H,KANGAWA K,MIYAZATO M.Update on ghrelin biology in birds[J].General and Comparative Endocrinology,2013,190:170-175.
[14] OC?O? E,PIETRAS M.Peripheral ghrelin inhibits feed intake through hypothalamo-pituitary-adrenal axis-dependent mechanism in chicken[J].Journal of Animal and Feed Sciences,2011,20(1):118-130.

[15] LIVAK K J,SCHMITTGEN T D.Analysis of relative gene expression data using real-time quantitative PCR and the 2
-ΔΔCT method[J].Methods,2001,25(4):402-408.

[16] HANAFUSA J,MUNE T,TANAHASHI T,et al.Altered corticosteroid metabolism differentially affects pituitary corticotropin response[J].American Journal of Physiology.Endocrinology and Metabolism,2002,282(2):E466-E473.
[17] CONTARINO A,GOLD L H.Targeted mutations of the corticotropin-releasing factor system:effects on physiology and behavior[J].Neuropeptides,2002,36(2/3):103-116.
[18] CLARK M S,KAIYALA K J.Role of corticotropin-releasing factor family peptides and receptors in stress-related psychiatric disorders[J].Seminars in Clinical Neuropsychiatry,2003,8(2):119-136.

[19] CONE R D.The corticotropin-releasing hormone system and feeding behavior-a complex web begins to unravel[J].Endocrinology,2000,141(8):2713-2714.

[20] CONNAN F,LIGHTMAN S L,LANDAU S,et al.An investigation of hypothalamic-pituitary-adrenal axis hyperactivity in anorexia nervosa:the role of CRH and AVP[J].Journal of Psychiatric Research,2007,41(1/2):131-143.
[21] YAKABI K,NOGUCHI M,OHNO S,et al.Urocortin 1 reduces food intake and ghrelin secretion via CRF(2) receptors[J].American Journal of Physiology,2011,301(1):E72-E82.
[22] ARASE K,YORK D A,SHIMIZU H,et al.Effects of corticotropin-releasing factor on food intake and brown adipose tissue thermogenesis in rats[J].American Journal of Physiology,1988,255(3 Pt 1):E255-E259.
[23] DENBOW D M,SNAPIR N,FURUSE M.Inhibition of food intake by CRF in chickens[J].Physiology & Behavior,1999,66(4):645-649.

[24] CLINE M A,KUO A Y,SMITH M L,et al.Differential feed intake responses to central corticotrophin releasing factor in lines of chickens divergently selected for low or high body weight[J].Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology,2009,152(1):130-134.

[25] FURUSE M,MATSUMOTO M,SAITO N,et al.The central corticotropin-releasing factor and glucagon-like peptide-1 in food intake of the neonatal chick[J].European Journal of Pharmacology,1997,339(2/3):211-213.
[26] CARSIA R V,WEBER H.Dietary protein restriction stress in the domestic chicken (
Gallus gallus domesticus) induces remodeling of adrenal steroidogenic tissue that supports hyperfunction[J].General and Comparative Endocrinology,2000,120(1):99-107.

[27] NEUFELD-COHEN A,TSOORY M M,EVANS A K,et al.A triple
urocortin knockout mouse model reveals an essential role for urocortins in stress recovery[J].Proceedings of the National Academy of Sciences of the United States of America,2010,107(44):19020-19025.

[28] SCHMIDT M E,ANDREWS R D,VAN DER ARK P,et al.Dose-dependent effects of the CRF1 receptor antagonist R317573 on regional brain activity in healthy male subjects[J].Psychopharmacology,2010,208(1):109-119.

[29] PELLEYMOUNTER M A,JOPPA M,CARMOUCHE M,et al.Role of corticotropin-releasing factor (CRF) receptors in the anorexic syndrome induced by CRF[J].Journal of Pharmacology & Experimental Therapeutics,2000,293(3):799-806.
[30] MARTÍNEZ V,TACHÉ Y.Role of CRF receptor 1 in central CRF-induced stimulation of colonic propulsion in rats[J].Brain Research,2001,893(1/2):29-35.
[31] GUALILLO O,LAGO F,GÓMEZ-REINO J,et al.Ghrelin,a widespread hormone:insights into molecular and cellular regulation of its expression and mechanism of action[J].FEBS Letters,2003,552(2/3):105-109.
[32] KOJIMA M,KANGAWA K.Ghrelin,an orexigenic signaling molecule from the gastrointestinal tract[J].Current Opinion in Pharmacology,2002,2(6):665-668.

[33] KAIYA H,KANGAWA K,MIYAZATO M.What is the general action of ghrelin for vertebrates?Comparisons of ghrelin's effects across vertebrates[J].General and Comparative Endocrinology,2013,181:187-191.
[34] SHOUSHA S,NAKAHARA K,KOJIMA M,et al.Different effects of peripheral and central ghrelin on regulation of food intake in the Japanese quail[J].General and Comparative Endocrinology,2005,141(2):178-183.

[35] SAITO E S,KAIYA H,TACHIBANA T,et al.Inhibitory effect of ghrelin on food intake is mediated by the corticotropin-releasing factor system in neonatal chicks[J].Regulatory Peptides,2005,125(1/2/3):201-208.
[36] SOARES J B,LEITE-MOREIRA A F.Ghrelin,des-acyl ghrelin and obestatin:three pieces of the same puzzle[J].Peptides,2008,29(7):1255-1270.

[37] TAMURA H,KAMEGAI J,SUGIHARA H,et al.Glucocorticoids regulate pituitary growth hormone secretagogue receptor gene expression[J].Journal of Neuroendocrinology,2001,12(6):481-485.