Effects of Polysaccharides from Portulaca oleracea L. on Growth Performance, Serum Biochemical Indices and Intestinal Morphology of Early-Weaned Rats

HUANG Xiaoliu, YAN Xiaoxing, ZHANG Tongtong, GAO Tianrui, ZHU Tianyu, PENG Xiaoyu

doi:10.3969/j.issn.1006-267x.2019.04.035

2019 , Vol. 31 >Issue 4: 1773 - 1780

DOI: https://doi.org/10.3969/j.issn.1006-267x.2019.04.035

Molecular Nutrition

Effects of Polysaccharides from Portulaca oleracea L. on Growth Performance, Serum Biochemical Indices and Intestinal Morphology of Early-Weaned Rats

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1. Department of Public Health, School of Medicine, Jinggangshan University, Ji'an 343009, China;
2. The First People's Hospital of Ji'an, Ji'an 343000, China

Received date: 2018-09-18

Online published: 2019-04-16

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Abstract

This experiment was conducted to investigate the effects of polysaccharides from Portulaca oleracea L. on growth performance, serum biochemical indices and intestinal morphology of early-weaned rats. A total of 30 SD early-weaned rats were selected and randomly divided into three groups with ten rats per group. Rats in the three groups were fed the same diet, and rats in group Ⅰ (control group) were given 2 mL normal saline by gavage once a day, while rats in groups Ⅱ and Ⅲ (trial groups) were given polysaccharides from Portulaca oleracea L. (dissolved in 2 mL normal saline) at the dosage of 100 and 200 mg/kg BW by gavage once a day, respectively. The experiment lasted for 28 days. The results showed as follows:1) polysaccharides from Portulaca oleracea L. had no significant differences in the body weight, average daily gain (ADG), average daily intake (ADFI), serum biochemical indices such as urea nitrogen (UN), triglycerides (TG), low density lipoprotein (LDL) contents and glutamate pyruvic transaminase (GPT) activity, villus height of ileum and colon length (P>0.05). 2) Compared with group Ⅰ, the serum biochemical indices such as total protein (TP), albumin (ALB), high density lipoprotein (HDL), glucose (GLU) contents and glutamic oxaloacetic transaminase (GOT) activity in groups Ⅱ and Ⅲ were significantly or extremely significantly increased (P<0.05 or P<0.01), and the villus height/crypt depth (V/C) of ileum and villus height of colon in groups Ⅱ and Ⅲ were significantly or extremely significantly enhanced (P<0.05 or P<0.01). 3) Compared with group Ⅰ, the serum biochemical indices such as globulin (GLO), total cholesterol (TC) contents and alkaline phosphatase (AKP) activity in group Ⅲ were significantly or extremely significantly increased (P<0.05 or P<0.01), and the feed/gain (F/G) and crypt depth of ileum were significantly or extremely significantly decreased (P<0.05 or P<0.01). The results indicate that polysaccharides from Portulaca oleracea L. can enhance the activities of relative metabolic enzymes and increase the contents of protein, cholesterol and glucose in serum, promote the development of intestinal villus, and reduce feed/gain with improving the growth performance of early-weaned rats.

Key words： polysaccharides from Portulaca oleracea L.; early-weaned rats; growth performance; serum biochemical indices; intestinal morphology

Cite this article

HUANG Xiaoliu, YAN Xiaoxing, ZHANG Tongtong, GAO Tianrui, ZHU Tianyu, PENG Xiaoyu . Effects of Polysaccharides from Portulaca oleracea L. on Growth Performance, Serum Biochemical Indices and Intestinal Morphology of Early-Weaned Rats[J]. Chinese Journal of Animal Nutrition, 2019 , 31(4) : 1773 -1780 . DOI: 10.3969/j.issn.1006-267x.2019.04.035

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