Effects of Attapulgite Nano Zinc Oxide on Antioxidant Indexes in Serum, Liver and Intestinal Mucosa of Weaned Piglets

MAO Junzhou, DONG Li, PENG Cheng, ZHANG Yongsheng, YU Lihuai

doi:10.3969/j.issn.1006-267x.2019.04.037

Chinese Journal of Animal Nutrition >

2019 , Vol. 31 >Issue 4: 1789 - 1796

DOI: https://doi.org/10.3969/j.issn.1006-267x.2019.04.037

Molecular Nutrition

Effects of Attapulgite Nano Zinc Oxide on Antioxidant Indexes in Serum, Liver and Intestinal Mucosa of Weaned Piglets

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College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China

Received date: 2018-09-12

Online published: 2019-04-16

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Abstract

This experiment was conducted to explore the effects of attapulgite nano zinc oxide on antioxidant indexes in serum, liver and intestinal mucosa of weaned piglets. A total of 210 healthy 21-day-old piglets with a similar body weight of (6.30±0.51) kg were randomly allocated into 7 groups with 6 replicates per group and 5 piglets per replicate. The 7 groups were control group (CON group, basal diet), antibiotic group (ANT group, basal diet+antibiotic), zinc oxide group (ZO group, basal diet+3 000 mg/kg zinc oxide), nano zinc oxide group (NZO group, basal diet+800 mg/kg nano zinc oxide), low dose attapulgite nano zinc oxide group (LANZ group, basal diet+700 mg/kg attapulgite nano zinc oxide), middle dose attapulgite nano zinc oxide group (MANZ group, basal diet+1 000 mg/kg attapulgite nano zinc oxide) and high dose attapulgite nano zinc oxide group (HANZ group, basal diet+1 300 mg/kg attapulgite nano zinc oxide). The pre-experimental period lasted for 3 days, and the experimental period lasted for 9 days. The results showed as follows:1) the serum catalase (CAT) activity of ZO and LANZ groups was significantly higher than that of CON group (P<0.05); the serum total antioxidant capacity (T-AOC) of ANT, ZO, LANZ, MANZ and HANZ groups was significantly higher than that of CON group (P<0.05), and the serum T-AOC of ANT group was significantly higher than that of other groups (P<0.05). 2) The liver CAT activity of LANZ group was significantly higher than that of other groups (P<0.05). 3) The jejunum mucosa superoxide dismutase (SOD) activity of ZO, NZO, LANZ, MANZ and HANZ groups was significantly higher than that of ANT group (P<0.05). The jejunum mucosa CAT activity of ZO and LANZ groups was significantly higher than that of CON and ANT groups (P<0.05). The jejunum mucosa T-AOC of ANT, ZO, NZO, LANZ and HANZ groups was significantly higher than that of CON and MANZ groups (P<0.05). 4) The ileal mucosa CAT activity of HANZ group was significantly lower than that of CON group (P<0.05), the ileal mucosa glutathione peroxidase (GSH-Px) activity of ZO and NZO groups was significantly lower than that of CON, ANT and LANZ groups (P<0.05). The results indicat that the appropriate supplementation of attapulgite nano zinc oxide can improve the activity of antioxidant enzymes in serum, liver and intestine, and enhance the antioxidant performance of piglets. The suitable supplementation of attapulgite nano zinc oxide is 700 mg/kg in this experiment.

Key words： attapulgite nano zinc oxide; serum; liver; intestinal mucosa; antioxidant

Cite this article

MAO Junzhou, DONG Li, PENG Cheng, ZHANG Yongsheng, YU Lihuai . Effects of Attapulgite Nano Zinc Oxide on Antioxidant Indexes in Serum, Liver and Intestinal Mucosa of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2019 , 31(4) : 1789 -1796 . DOI: 10.3969/j.issn.1006-267x.2019.04.037

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