Effects of Fermentation Diet without Antibiotic on Intestinal Mucosal Morphology and Goblet Cells of Piglets

WEI Xiaobing, ZHANG Xiulin, WANG Qiuxia, LIU Mingcheng, ZHU Hongxiao, HU Huilong, LIU Xingyou

doi:10.3969/j.issn.1006-267x.2019.04.038

Chinese Journal of Animal Nutrition >

2019 , Vol. 31 >Issue 4: 1797 - 1805

DOI: https://doi.org/10.3969/j.issn.1006-267x.2019.04.038

Molecular Nutrition

Effects of Fermentation Diet without Antibiotic on Intestinal Mucosal Morphology and Goblet Cells of Piglets

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1. College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology, Xinxiang 453003, China;
2. Animal Viral Disease Control and Residual Analysis Henan Higher Education Key Discipline Open Laboratory, Xinxiang 453003, China;
3. Intelligent Cleaner Production of Livestock and Poultry of Henan Provincial Engineering Laboratory, Xinxiang 453003, China;
4. Xinxiang University, Xinxiang 453003, China

Received date: 2018-09-12

Online published: 2019-04-16

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Abstract

This experiment was conducted to study the effects of fermentation diet without antibiotic on morphology of intestinal mucosa and goblet cells for piglets. A total of 120 suckling piglets with similar body weight were randomly divided into control group and test group with 6 replicates per group and 10 piglets per replicate. Piglets in the control groups were fed the basal diet containing antibiotics; piglets in the test group were fed the non-antibiotic basal diet with 10% fermentation diet, and its levels of nutrition and energy were the same as the control group. The results showed as follows:1) there was a certain difference in mucosal morphology between the test group and the control group. 2) At 44 days of age, the villus height of jejunum in test group was significantly increased by 7.19% compared with control group (P<0.05). At 44 and 75 days of age, the villus height of ileum in test group was significantly higher than that in control group (P<0.05). 3) Crypt depth of duodenum, jejunum, ileum in the test group was lower than that of the control group, but not significant (P>0.05). 4) At 44 days of age, villus height/crypt depth (V/C) of ileum in test group was significantly increased by 17.18% compared with the control group (P<0.05). 5) At 44 days of age, the number of goblet cells of duodenum, jejunum and ileum in control group was significantly higher than that in test group (P<0.01). At 75 days of age, the number of goblet cells of duodenal in control group was significantly higher than that in the control group (P<0.01). In conclusion, the fermentation diet without antibiotic can improve the intestinal mucosa morphology and enlarge the absorption area, thus promoting absorption of nutrients by small intestine.

Key words： fermentation diet without antibiotic; piglets; small intestinal mucosa; goblet cell

Cite this article

WEI Xiaobing, ZHANG Xiulin, WANG Qiuxia, LIU Mingcheng, ZHU Hongxiao, HU Huilong, LIU Xingyou . Effects of Fermentation Diet without Antibiotic on Intestinal Mucosal Morphology and Goblet Cells of Piglets[J]. Chinese Journal of Animal Nutrition, 2019 , 31(4) : 1797 -1805 . DOI: 10.3969/j.issn.1006-267x.2019.04.038

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