Effects of Melatonin on Nucleotides Binding Oligomeric Domain Receptor Protein 3 Inflammatory Corpuscle and Its Mechanisms

QIN Chunli, LYU Jingzhi, HE Zhifei, LI Hongjun

doi:10.3969/j.issn.1006-267x.2019.05.013

2019 , Vol. 31 >Issue 5: 2069 - 2075

DOI: https://doi.org/10.3969/j.issn.1006-267x.2019.05.013

Molecular Nutrition

Effects of Melatonin on Nucleotides Binding Oligomeric Domain Receptor Protein 3 Inflammatory Corpuscle and Its Mechanisms

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1. College of Animal Science and Technology, Southwest University, Chongqing 400715, China;
2. College of Food Science, Southwest University, Chongqing 400715, China

Received date: 2018-10-15

Online published: 2019-05-15

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Abstract

With the continuous improvement of intensive production level of animal husbandry, the economic losses caused by animal inflammation have been paid more and more attention. Toll-like receptors on cell surface can induce the expression of nucleotide-binding oligomeric domain-like receptor protein-3 inflammatory corpuscle by activating intracytoplasmic nuclear transcription factor-kappa B, and aggravate the inflammatory response. This article reviews the nucleotide-binding oligomeric receptor protein-3 inflammatory corpuscle and inflammatory diseases, the effects of melatonin on Toll-like receptors, nuclear transcription factor-kappa B and nucleotide-binding oligomeric receptor protein-3 inflammatory corpuscle, and the effects of inflammation on animal production.

Key words： NLRP3 inflammatory corpuscle; melatonin; mechanisms; inflammatory diseases

Cite this article

QIN Chunli, LYU Jingzhi, HE Zhifei, LI Hongjun . Effects of Melatonin on Nucleotides Binding Oligomeric Domain Receptor Protein 3 Inflammatory Corpuscle and Its Mechanisms[J]. Chinese Journal of Animal Nutrition, 2019 , 31(5) : 2069 -2075 . DOI: 10.3969/j.issn.1006-267x.2019.05.013

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