Molecular Nutrition

Fatty Acid Translocase CD36/SR-B2 and Its Mediation in Transmembrane Transportation of Long-Chain Fatty Acids

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  • 1. College of Animal Science, Southwest University, Chongqing 402460, China;
    2. Key Laboratory for Agri-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Research Center of Livestock and Poultry Sciences, South Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, China;
    3. Xishui Fuxing Husbandry Co., Ltd., Xishui 556400, China;
    4. Baiyu Muwang Agricultural Science and Technology Co., Ltd., Baiyu 627150, China;
    5. Baiyu Yumu Fengyuan Animal Husbandry Science and Technology Co., Ltd., Baiyu 627150, China

Received date: 2018-12-04

  Online published: 2019-06-17

Abstract

Long-chain fatty acids are important nutrients to maintain normal metabolism of the body, its absorption, transportation and metabolism have important influences on the health, growth and production of animals. In recent years, researchers have found that some fatty acid transporter proteins mediated the transportation of long-chain fatty acids across the membrane. The fatty acid translocase CD36/SR-B2 is an integrated membrane protein, which could specifically regulate the transmembrane transportation of fatty acids in many different types of cells. This paper reviewed the current understanding, subcellular localization, functional regulation of CD36/SR-B2 and the transmembrane transportation of long-chain fatty acids mediated by CD36/SR-B2, and also discussed the regulation mechanism of lipid metabolism by CD36/SR-B2.

Cite this article

LUO Dongmei, WANG Shuiping, ZHAO Xueli, HAN Xuefeng . Fatty Acid Translocase CD36/SR-B2 and Its Mediation in Transmembrane Transportation of Long-Chain Fatty Acids[J]. Chinese Journal of Animal Nutrition, 2019 , 31(6) : 2552 -2559 . DOI: 10.3969/j.issn.1006-267x.2019.06.014

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