Effects of Dietary Glutathione on Growth Performance, Serum Biochemical Indices and Antioxidant Capacity of Juvenile Lateolabrax japonicus

LI Guoming, SUN Yuping, WANG Guoxia, CHEN Bing, HUANG Yanhua, WANG Yongmei, CAO Junming

doi:10.3969/j.issn.1006-267x.2019.07.032

2019 , Vol. 31 >Issue 7: 3207 - 3217

DOI: https://doi.org/10.3969/j.issn.1006-267x.2019.07.032

Molecular Nutrition

Effects of Dietary Glutathione on Growth Performance, Serum Biochemical Indices and Antioxidant Capacity of Juvenile Lateolabrax japonicus

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1. College of Fisheries and Life Sciences, Shanghai Ocean University, Shanghai 201306, China;
2. Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China;
3. Key Laboratory of Animal Nutrition and Feed Science in South China of Ministry of Agriculture, Guangzhou 510640, China;
4. Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou 510640, China

Received date: 2018-12-11

Online published: 2019-07-19

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Abstract

This experiment was conducted to evaluate the effects of dietary glutathione on growth performance, serum biochemical indices and antioxidant capacity of juvenile Lateolabrax japonicus. A total of 600 Lateolabrax japonicus with initial body weight of (12.56±0.12) g were randomly divided into 6 groups with 4 replicates per group and 25 fish per replicate. Fish in the control group were fed a basal diet, and the others in the experimental groups were fed the basal diet supplemented with 100, 300, 400, 500 and 700 mg/kg glutathione, respectively. The trial lasted for 56 days. The results showed as follows:1) there were no significant differences in growth performance and routine nutritional component indices among all groups (P>0.05). 2) Compared with the control group, the contents of glucose and urea nitrogen in serum in 100 mg/kg group and the glucose content and aspartate aminotransferase, alanine aminotransferase activities in serum in 700 mg/kg group were significantly increased (P<0.05). 3) Compared with the control group, the serum total antioxidant, glutathione content and glutathione perxidase activity in 500 and 700 mg/kg groups and the serum glutathione transferase activity in all experimental groups were significantly increased (P<0.05). 4) Compared with the control group, the liver superoxide dismutase activity in 300 and 400 mg/kg groups and the liver glutathione perxidase activity in 100, 400, 500 and 700 mg/kg groups were significantly increased (P<0.05), and the liver glutathione transferase activity in 100 and 700 mg/kg groups was significantly decreased (P<0.05). 5) Compared with the control group, the liver interleukin-6 content in 300 mg/kg group was significantly increased (P<0.05). In conclusion, dietary glutathoine can improve the antioxidant indices in serum and liver of Lateolabrax japonicus, but it has a negative impact on some antioxidant indexes and liver inflammatory factors. Therefore, under the condition of the basal diet in this experiment, glutathione should be carefully added into the diet of Lateolabrax japonicus.

Key words： glutathione; Lateolabrax japonicus; growth performance; serum biochemical indices; antioxidant capacity

Cite this article

LI Guoming, SUN Yuping, WANG Guoxia, CHEN Bing, HUANG Yanhua, WANG Yongmei, CAO Junming . Effects of Dietary Glutathione on Growth Performance, Serum Biochemical Indices and Antioxidant Capacity of Juvenile Lateolabrax japonicus[J]. Chinese Journal of Animal Nutrition, 2019 , 31(7) : 3207 -3217 . DOI: 10.3969/j.issn.1006-267x.2019.07.032

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