Effects of Selenium-Enrich Exopoly Saccharide on Growth Performance, Antioxidant Function, Intestinal Morphology and Antibacterial Peptide Expression of Weaned Piglets

  • LU Zeqing ,
  • HU Yuhan ,
  • HUANG Xiangyun ,
  • ZHANG Yu ,
  • WANG Fengqin ,
  • WANG Yizhen
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  • National Engineering Laboratory of Biological Feed Safety and Pollution Prevention and Control, Key Laboratory of Animal Nutrition and Feed Science in Eastern China, Zhejiang Provincial Laboratory of Feed and Animal Nutrition, Ministry of Agriculture, Institute of Feed Science, Zhejiang University, Hangzhou 310058, China

Received date: 2019-01-31

  Online published: 2019-08-19

Abstract

This experiment was conducted to investigate the effects exopoly saccharides (EPS) and selenium-enriched exopoly saccharides (Se-EPS) produced by Enterobacter cloacae Z0206 on growth performance, antioxidant function, intestinal morphology and antibacterial peptide expression of weaned piglets. A total of 150 piglets (Landrace×Yorkshire×Duroc) weaned at 28 days of age with similar body weight were randomly allocated into 5 groups with 3 replicates per group and 10 pigs per replicate. Pigs in the control (CON) group were fed a basal diet, pigs in the sodium selenite (Na2SeO3) group fed the basal diet+0.30 mg/kg Na2SeO3, pigs in the Na2SeO3+ astragalus polysaccharides (APS) group fed the basal diet+0.30 mg/kg Na2SeO3+560 mg/kg APS, pigs in the Na2SeO3+EPS group fed the basal diet+0.30 mg/kg Na2SeO3+560 mg/kg EPS, and pigs in the Se-EPS group fed the basal diet+560 mg/kg Se-EPS. The experiment lasted for 39 days. The results showed that compared with Na2SeO3 group, dietary supplemented with Se-EPS significantly increased the average daily gain of weaned piglets (P<0.05), significantly decreased the ratio of feed to gain (P<0.05), significantly increased the serum total antioxidant capacity (P<0.05), and significantly decreased the serum malondialdehyde content (P<0.05). Compared with the control group, dietary supplemented with Na2SeO3+EPS and Se-EPS significantly increased the villus height and villus height/crypt depth (V/C) in jejunum of weaned piglets (P<0.05), and dietary supplemented with Se-EPS significantly increased the mRNA relative expression of porcine β-defensin 1 (pBD-1) in duodenum and porcine β-defensin 2 (pBD-2) in jejunum and ileum (P<0.05). In conclusion, dietary supplemented with Se-EPS can improve the growth performance and antioxidant function, and promote intestinal endogenous antimicrobial peptide expression of weaned piglets.

Cite this article

LU Zeqing , HU Yuhan , HUANG Xiangyun , ZHANG Yu , WANG Fengqin , WANG Yizhen . Effects of Selenium-Enrich Exopoly Saccharide on Growth Performance, Antioxidant Function, Intestinal Morphology and Antibacterial Peptide Expression of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2019 , 31(8) : 3755 -3762 . DOI: 10.3969/j.issn.1006-267x.2019.08.037

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