[1] D'ANIELLO A.
D-aspartic acid:an endogenous amino acid with an important neuroendocrine role[J].Brain Research Reviews,2007,53(2):215-234.
[2] D'ANIELLO A,GIUDITTA A.Identification of
D-aspartic acid in the brain of
Octopus vulgaris lam[J].Journal of Neurochemistry,1977,29(6):1053-1057.
[3] NEIDLE A,DUNLOP D S.Developmental changes in free
D-aspartic acid in the chicken embryo and in the neonatal rat[J].Life Sciences,1990,46(21):1517-1522.
[4] DUNLOP D S,NEIDLE A,MCHALE D,et al.The presence of free
D-aspartic acid in rodents and man[J].Biochemical and Biophysical Research Communications,1986,141(1):27-32.
[5] D'ANIELLO A,DI FIORE M M,FISHER G H,et al.Occurrence of
D-aspartic acid and N-methyl-
D-aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth hormone release[J].The FASEB Journal,2000,14(5):699-714.
[6] ERRICO F,NISTICÒ R,NAPOLITANO F,et al.Increased
D-aspartate brain content rescues hippocampal age-related synaptic plasticity deterioration of mice[J].Neurobiology of Aging,2011,32(12):2229-2243.
[7] LI Y Y,HAN H,YIN J,et al.
D- and
L-aspartate regulates growth performance,inflammation and intestinal microbial community in young pigs[J].Food & Function,2019,10(2):1028-1037.
[8] JORGE V,NICOLE T,FARID H S,et al.
D-aspartic acid beta-hydroxamate for the treatment of viral infections and tumors:US,US5571839[P].1996-11-05.
[9] YANAGIDA T,KOJIMA Y,YAMASAKI K,et al.Studies on structures of degradation products of aspoxicillin.Ⅱ.Polymerization products of aspoxicillin in aqueous solution[J].Yakugaku Zasshi,1990,110(6):400-406.
[10] 代书玲,徐虹,欧阳平凯.
D-天冬氨酸的制备和应用[J].南京工业大学学报,2003,25(2):108-110.
[11] LEE J A,HOMMA H,TASHIRO K,et al.
D-aspartate localization in the rat pituitary gland and retina[J].Brain Research,1999,838(1/2):193-199.
[12] D'ANIELLO S,SPINELLI P,FERRANDINO G,et al.Cephalopod vision involves dicarboxylic amino acids:
D-aspartate,
L-aspartate and
L-glutamate[J].Biochemical Journal,2005,386:331-340.
[13] HUANG A S,LEE D A,BLACKSHAW S.
D-aspartate and d-aspartate oxidase show selective and developmentally dynamic localization in mouse retina[J].Experimental Eye Research,2008,86(4):704-709.
[14] FURUCHI T,HOMMA H.Free
D-aspartate in mammals[J].Biological & Pharmaceutical Bulletin,2005,28(9):1566-1570.
[15] D'ANIELLO A,LEE J M,PETRUCELLI L,et al.Regional decreases of free
D-aspartate levels in Alzheimer's disease[J].Neuroscience Letters,1998,250(2):131-134.
[16] ERRICO F,NISTICÒ R,PALMA G,et al.Increased levels of
D-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibility[J].Molecular and Cellular Neuroscience,2008,37(2):236-246.
[17] ERRICO F,ROSSI S,NAPOLITANO F,et al.
D-aspartate prevents corticostriatal long-term depression and attenuates schizophrenia-like symptoms induced by amphetamine and MK-801[J].Journal of Neuroscience,2008,28(41):10404-10414.
[18] TOPO E,SORICELLI A,DI MAIO A,et al.Evidence for the involvement of
D-aspartic acid in learning and memory of rat[J].Amino Acids,2010,38(5):1561-1569.
[19] KIM P M,DUAN X,HUANG A S,et al.Aspartate racemase,generating neuronal
D-aspartate,regulates adult neurogenesis[J].Proceedings of the National Academy of Sciences of the United States of America,2010,107(7):3175-3179.
[20] TSURUGIZAWA T,UNEYAMA H,TORⅡ K.Brain amino acid sensing[J].Diabetes,Obesity and Metabolism,2014,16(S1):41-48.
[21] D'ANIELLO S,SOMORJAI I,GARCIA-FERNÀNDEZ J,et al.
D-aspartic acid is a novel endogenous neurotransmitter[J].The FASEB Journal,2011,25(3):1014-1027.
[22] GENCHI G.An overview on
D-amino acids[J].Amino Acids,2017,49(9):1521-1533.
[23] LONG Z Q,LEE J A,OKAMOTO T,et al.
D-aspartate in a prolactin-secreting clonal strain of rat pituitary tumor cells (GH
3)[J].Biochemical and Biophysical Research Communications,2000,276(3):1143-1147.
[24] SAKAI K,HOMMA H,LEE J A,et al.
D-aspartic acid localization during postnatal development of rat adrenal gland[J].Biochemical and Biophysical Research Communications,1997,235(2):433-436.
[25] WOLOSKER H,D'ANIELLO A,SNYDER S H.
D-aspartate disposition in neuronal and endocrine tissues:ontogeny,biosynthesis and release[J].Neuroscience,2000,100(1):183-189.
[26] HASHIMOTO A,OKA T,NISHIKAWA T.Anatomical distribution and postnatal changes in endogenous free
D-aspartate and
D-serine in rat brain and periphery[J].European Journal of Neuroscience,1995,7(8):1657-1663.
[27] GONZÁLEZ S L,LABOMBARDA F,GONZÁLEZ DENISELLE M C,et al.Progesterone up-regulates neuronal brain-derived neurotrophic factor expression in the injured spinal cord[J].Neuroscience,2004,125(3):605-614.
[28] TAKAO T,FLINT N,LEE L,et al.17beta-estradiol protects oligodendrocytes from cytotoxicity induced cell death[J].Journal of Neurochemistry,2004,89(3):660-673.
[29] GIATTI S,CARUSO D,BORASO M,et al.Neuroprotective effects of progesterone in chronic experimental autoimmune encephalomyelitis[J].Journal of Neuroendocrinology,2012,24(6):851-861.
[30] AFRAEI S,D'ANIELLO A,SEDAGHAT R,et al.Therapeutic effects of
D-aspartate in a mouse model of multiple sclerosis[J].Journal of Food and Drug Analysis,2017,25(3):699-708.
[31] YE J N,CHEN X S,SU L,et al.Progesterone alleviates neural behavioral deficits and demyelination with reduced degeneration of oligodendroglial cells in cuprizone-induced mice[J].PLoS One,2013,8(1):e54590.
[32] DI FIORE M M,SANTILLO A,FALVO S,et al.Molecular mechanisms elicited by
D-aspartate in leydig cells and spermatogonia[J].International Journal of Molecular Sciences,2016,17(7):1127.
[33] DI FIORE M M,BURRONE L,SANTILLO A,et al.Endocrine activity of
D-aspartate in nonmammalian animals[M]//YOSHIMURA T,NISHIKAWA T,HOMMA H.
D-amino acids:physiology,metabolism,and application.Tokyo:Springer,2016:157-172.
[34] MILLER W L.Molecular biology of steroid hormone synthesis[J].Endocrine Reviews,1988,9(3):295-318.
[35] MILLER W L.StAR search-what we know about how the steroidogenic acute regulatory protein mediates mitochondrial cholesterol import[J].Molecular Endocrinology,2007,21(3):589-601.
[36] CARREAU S,BOURAIMA-LELONG H,DELALANDE C.Estrogens in male germ cells[J].Spermatogenesis,2011,1(2):90-94.
[37] DI FIORE M M,SANTILLO A,FALVO S,et al.Sex hormone levels in the brain of
D-aspartate-treated rats[J].Comptes Rendus Biologies,2018,341(1):9-15.
[38] WALKER W H.Testosterone signaling and the regulation of spermatogenesis[J].Spermatogenesis,2011,1(2):116-120.
[39] SANTILLO A,FALVO S,CHIEFFI P,et al.
D-aspartate affects NMDA receptor-extracellular signal-regulated kinase pathway and upregulates androgen receptor expression in the rat testis[J].Theriogenology,2014,81(5):744-751.
[40] SANTILLO A,FALVO S,CHIEFFI P,et al.
D-aspartate induces proliferative pathways in spermatogonial GC-1 cells[J].Journal of Cellular Physiology,2016,231(2):490-495.
[41] DI NISIO A,DE TONI L,FERIGO M,et al.
D-aspartic acid stimulates steroidogenesis through the delay of LH receptor internalization in a mammalian Leydig cell line[J].Journal of Endocrinological Investigation,2016,39(2):207-213.
[42] FALVO S,DI FIORE M M,BURRONE L,et al.Androgen and oestrogen modulation by
D-aspartate in rat epididymis[J].Reproduction,Fertility and Development,2016,28(12):1865-1872.
[43] TOMITA K,TANAKA H,KAGEYAMA S,et al.The effect of
D-aspartate on spermatogenesis in mouse testis[J].Biology of Reproduction,2016,94(2):30.
[44] ANSARI M,ZHANDI M,KOHRAM H,et al.Improvement of post-thawed sperm quality and fertility of Arian rooster by oral administration of
D-aspartic acid[J].Theriogenology,2017,92:69-74.
[45] BARBATO V,TALEVI R,BRAUN S,et al.Supplementation of sperm media with zinc,
D-aspartate and co-enzyme Q10 protects bull sperm against exogenous oxidative stress and improves their ability to support embryo development[J].Zygote,2017,25(2):168-175.
[46] CHANDRASHEKAR K N,MURALIDHARA.
D-aspartic acid induced oxidative stress and mitochondrial dysfunctions in testis of prepubertal rats[J].Amino Acids,2010,38(3):817-827.
[47] LI Y Y,HAN H,YIN J,et al.Role of
D-aspartate on biosynthesis,racemization,and potential functions:a mini-review[J].Animal Nutrition,2018,4(3):311-315.
[48] BERG C P.Physiology of the
D-amino acids[J].Physiological Reviews,1953,33(2):145-189.
[49] ERWAN E,TOMONAGA S,OHMORI T,et al.Oral administration of
D-aspartate,but not of
L-aspartate,reduces food intake in chicks[J].The Journal of Poultry Science,2013,50(2):164-171.
[50] MARUYAMA K,SUNDE M L,HARPER A E.Effect of
D-alanine and
D-aspartic acid on the chick[J].The Journal of Nutrition,1972,102(11):1441-1451.
[51] KAMATH S H,BERG C P.Antagonism of the
D-forms of the essential amino acids toward the promotion of growth by
D-histidine[J].The Journal of Nutrition,1964,82(2):243-248.
[52] MARRETT L E,SUNDE M L.The effect of other
D-amino acids on the utilization of the isomers of methionine and its hydroxy analogue[J].Poultry Science,1965,44(4):957-964.
[53] DO P H,TRAN P V,BAHRY M A,et al.Oral administration of a medium containing both
D-aspartate-producing live bacteria and
D-aspartate reduces rectal temperature in chicks[J].British Poultry Science,2017,58(5):569-577.
[54] ERWAN E,TOMONAGA S,YOSHIDA J,et al.Central administration of
L- and
D-aspartate attenuates stress behaviors by social isolation and CRF in neonatal chicks[J].Amino Acids,2012,43(5):1969-1976.
