Effects of Artemisia argyi Aqueous Extract on Intestinal Mucosal Morphology of Broilers Stimulated with Lipopolysaccharide

ZHANG Linghui; DU Haidong; MAO Chenyu; ZHANG Pengfei; JIN Xiao; XU Yuanqing; SHI Binlin

doi:10.3969/j.issn.1006-267x.2019.11.042

2019 , Vol. 31 >Issue 11: 5256 - 5261

DOI: https://doi.org/10.3969/j.issn.1006-267x.2019.11.042

Effects of Artemisia argyi Aqueous Extract on Intestinal Mucosal Morphology of Broilers Stimulated with Lipopolysaccharide

ZHANG Linghui ,
DU Haidong ,
MAO Chenyu ,
ZHANG Pengfei ,
JIN Xiao ,
XU Yuanqing ,
SHI Binlin

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College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China

Received date: 2019-04-15

Online published: 2019-11-19

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Abstract

This experiment was conducted to investigate the effects of Artemisia argyi aqueous extract (AAE) on intestinal mucosal morphology of broilers stimulated with lipopolysaccharide (LPS). A total of 96 one-day-old AA broilers were randomly divided into 4 treatments (6 replicates per treatment, 4 broilers per replicate). Treatments 1 and 2 were fed a basal diet, and treatments 3 and 4 were fed the basal diet supplemented with 1 000 mg/kg AAE. On days 14, 16, 18 and 20, respectively, the broilers in treatments 2 and 4 were intraperitoneally injected with LPS solution at a dose of 500 μg/kg BW, and the broilers in treatments 1 and 3 were injected with the same amount of normal saline. The test period was 21 days. The results showed as follows:when no AAE was added in diets, the villus height of duodenum and jejunum of broilers injected with LPS was significantly lower than that of broilers injected with normal saline (P<0.05), but the addition of AAE to the diet alleviated the decrease of villus height caused by LPS, and there was significant interaction between AAE and LPS (P<0.05); but for ileum, there were no significant differences in villus height, crypt depth, and the ratio of villus height to crypt depth (P>0.05). The above results suggest that AAE can alleviate the intestinal mucosal damage caused by immune stress in broilers stimulated with LPS to a certain extent.

Key words： Artemisia argyi aqueous extract; broiler; intestinal mucosal morphology; lipopolysaccharide

Cite this article

ZHANG Linghui , DU Haidong , MAO Chenyu , ZHANG Pengfei , JIN Xiao , XU Yuanqing , SHI Binlin . Effects of Artemisia argyi Aqueous Extract on Intestinal Mucosal Morphology of Broilers Stimulated with Lipopolysaccharide[J]. Chinese Journal of Animal Nutrition, 2019 , 31(11) : 5256 -5261 . DOI: 10.3969/j.issn.1006-267x.2019.11.042

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