Effects of Clostridium butyricum on Growth Performance and Serum Biochemical Indices of Broilers

ZHENG Aijuan; WU Zhengke; PIRZADO Shoaib Ahmed; CAI Huiyi; CHEN Zhimin; CHANG Wenhuan; DENG Xuejuan; LIU Guohua

doi:10.3969/j.issn.1006-267x.2019.12.017

Chinese Journal of Animal Nutrition >

2019 , Vol. 31 >Issue 12: 5519 - 5525

DOI: https://doi.org/10.3969/j.issn.1006-267x.2019.12.017

Effects of Clostridium butyricum on Growth Performance and Serum Biochemical Indices of Broilers

ZHENG Aijuan ,
WU Zhengke ,
PIRZADO Shoaib Ahmed ,
CAI Huiyi ,
CHEN Zhimin ,
CHANG Wenhuan ,
DENG Xuejuan ,
LIU Guohua

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1. Key Laboratory of Feed Biotechnology of Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China;
2. National Engineering Research Center for Biological Feed Development, Beijing 100081, China

Received date: 2019-05-20

Online published: 2019-12-13

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Abstract

The present study evaluated the effects of Clostridium butyricum on growth performance and serum biochemical indices by adding it into the basal diet of broilers. One hundred and eighty 1-day-old healthy Arbor Acres broiler chickens were randomly allotted to three groups as the control group without antibiotic (non-antibiotic control group), antibiotic group and Clostridium butyricum group with six replicates per group and 10 chickens per replicate. Broilers in the non-antibiotic control group were fed the basal diet, those in the antibiotic group were fed the basal diet supplemented with 5 mg/kg flavomycin, 75 mg/kg aureomycin and 20 mg/kg kitasamycin, and those in the Clostridium butyricum group were fed the basal diet supplemented with 2.5×10⁸ CFU/kg Clostridium butyricum for 42 days. The results showed as follows:1) the supplementation of Clostridium butyricum did not significantly affect body weight of broilers at 21 and 42 days of age, as well as average daily gain and feed to gain ratio of broilers from 1 to 21 days of age (P>0.05). Compared with the non-antibiotic control group, the supplementation of Clostridium butyricum significantly reduced the average daily feed intake of broilers from 1 to 21 days of age (P<0.05). 2) Compared with the non-antibiotic control group and the antibiotic group, the supplementation of Clostridium butyricum significantly increased the serum contents of triglyceride and total cholesterol and alkaline phosphatase activity of 42-day-old broilers (P<0.05). 3) Compared with the non-antibiotic control group or the antibiotic group, the supplementation of Clostridium butyricum significantly increased the serum contents of total protein, albumin and globulin of 42-day-old broilers (P<0.05). Compared with the non-antibiotic control group, the supplementation of Clostridium butyricum extremely significantly decreased serum ammonia content of 21- and 42-day-old broilers (P<0.01), and significantly decreased the serum uric acid content of 21-day-old broilers (P<0.05). In conclusion, the supplementation of Clostridium butyrate can significantly improve lipid metabolism, increase the serum protein content, and decrease the content of protein metabolites of broilers.

Key words： Clostridium butyricum; broilers; growth performance; serum biochemical indices

Cite this article

ZHENG Aijuan , WU Zhengke , PIRZADO Shoaib Ahmed , CAI Huiyi , CHEN Zhimin , CHANG Wenhuan , DENG Xuejuan , LIU Guohua . Effects of Clostridium butyricum on Growth Performance and Serum Biochemical Indices of Broilers[J]. Chinese Journal of Animal Nutrition, 2019 , 31(12) : 5519 -5525 . DOI: 10.3969/j.issn.1006-267x.2019.12.017

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