Effects of 5-Hydroxytryptamine Precursor on Lactation Performance and Plasma Biochemical Indexes of Perinatal Ewes

SANG Dan; NAMIRGA; SUN Haizhou; JIN Lu; ZHANG Chongzhi; ZHANG Chunhua; WANG Shuangsuo; LIU Yongjun; AO Changjin

doi:10.3969/j.issn.1006-267x.2019.12.026

Chinese Journal of Animal Nutrition >

2019 , Vol. 31 >Issue 12: 5601 - 5612

DOI: https://doi.org/10.3969/j.issn.1006-267x.2019.12.026

Effects of 5-Hydroxytryptamine Precursor on Lactation Performance and Plasma Biochemical Indexes of Perinatal Ewes

SANG Dan ,
NAMIRGA ,
SUN Haizhou ,
JIN Lu ,
ZHANG Chongzhi ,
ZHANG Chunhua ,
WANG Shuangsuo ,
LIU Yongjun ,
AO Changjin

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1. College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China;
2. Animal Nutrition and Feed Research Institution of Inner Mongolia Academy of Agriculture and Animal Husbandry Academy, Hohhot 010031, China;
3. Urat Front Banner Livestock Improvement Station, Bayannur 014400, China

Received date: 2019-06-24

Online published: 2019-12-13

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Abstract

This study was conducted to investigate the effect of 5-hydroxytryptamine (5-HT) precursor on lactation performance and plasma biochemical indexes of perinatal ewes. Thirty ewes of Bamei sheep in the same perinatal period with good body condition and body weight of (64.52±4.11) kg were randomly divided into 3 groups which were control group, 5-hydroxy-tryptophan (5-HTP) group (perfused 5-HTP) and tryptophan (Trp) group (perfused Trp), respectively, each group contained 10 ewes. Ewes jugular vein perfusion was conducted from prenatal day 7 to postpartum day 0, the perfusion dose of 5-HTP and Trp was 0.178 mg/kg BW, and the concentration was 0.1 mg/mL; the control group was perfused with the same dose of saline. The experiment lasted form prenatal day 7 to postpartum day 30. The results showed as follows:1) 5-HTP and Trp had no significant effects on milk yield and milk protein content of ewes (P>0.05), but significantly decreased the milk fat and milk non-fat solid content of ewes at postpartum day 3 (P<0.05). 2) 5-HTP and Trp could significantly increase the plasma 5-HT concentration of ewes at prenatal day 0 and postpartum days 3, 6 and 9 (P<0.05). 3) 5-HTP and Trp could significantly increase the plasma glucose concentration of ewes at prenatal day 0 and postpartum days 3, 6 and 9 (P<0.05), significantly decreased the plasma non-esterified fatty acid (NEFA) concentration of ewes at prenatal day 0 and postpartum days 3 and 9 (P<0.05), and significantly decreased the plasma insulin (INS) concentration of ewes at prenatal day 0 and postpartum days 3 and 6 (P<0.05). In conclusion, perfused 5-HT precursor can affect the milk fat and milk non-fat solid content of perinatal ewes, increase the plasma glucose concentration, and decrease the plasma NEFA and INS concentrations.

Key words： 5-HT; lactation performance; plasma biochemical indexes; ewes

Cite this article

SANG Dan , NAMIRGA , SUN Haizhou , JIN Lu , ZHANG Chongzhi , ZHANG Chunhua , WANG Shuangsuo , LIU Yongjun , AO Changjin . Effects of 5-Hydroxytryptamine Precursor on Lactation Performance and Plasma Biochemical Indexes of Perinatal Ewes[J]. Chinese Journal of Animal Nutrition, 2019 , 31(12) : 5601 -5612 . DOI: 10.3969/j.issn.1006-267x.2019.12.026

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