Molecule Mechanism of Niacin Regulate Intestinal Epithelial Barrier Function of Animals

  • QIU Yueqin ,
  • YANG Xuefen ,
  • WANG Li ,
  • JIANG Zongyong
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  • 1. Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Livestock and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science of Ministry of Agriculture in South China, Guangdong Public Laboratory of Animal Breeding and Nutrition, Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou 510640, China;
    2. College of Animal Science, South China Agricultural University, Guangzhou 510640, China

Received date: 2019-08-05

  Online published: 2020-02-21

Abstract

As an important vitamin, niacin plays important effects on prevention intestinal inflammation and maintaining intestinal healthy and other aspects. Research shows that niacin can directly bind to niacin receptor G protein-coupled receptor 109A (GPR109A) to play its physiological role, and partakes in cell energy metabolism in form of coenzyme nicotinamide adenine dinucleotide (NAD+). This review mainly expounded the mechanism of niacin maintaining intestinal mucosal barrier function, to provide the scientific theoretical basis for maintaining intestinal health of weaned piglets.

Cite this article

QIU Yueqin , YANG Xuefen , WANG Li , JIANG Zongyong . Molecule Mechanism of Niacin Regulate Intestinal Epithelial Barrier Function of Animals[J]. Chinese Journal of Animal Nutrition, 2020 , 32(2) : 481 -486 . DOI: 10.3969/j.issn.1006-267x.2020.02.001

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