Biological Function of Rosemary Extract and Its Application in Animal Production

  • DUAN Guangying ,
  • PENG Fang ,
  • SONG Zehe ,
  • FAN Zhiyong
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  • College of Animal Science and Technology, Hunan Co-Innovation Center of Animal Production Safety, Hunan Engineering Research Center of Poultry Production Safety, Hunan Agricultural University, Changsha 410128, China

Received date: 2019-07-14

  Online published: 2020-02-21

Abstract

Rosemary and rosemary extract have many biological functions such as anti-oxidation, bacteriostatic, anti-tumor, anti-inflammatory, hypolipidemic and liver protection. Therefore, they have been long concerned by people at home and abroad. This paper reviews the absorption and metabolism, biological functions of rosemary extract and its application in animal production, and aims to provide a theoretical basis for further development of the application of rosemary extract in animal production.

Cite this article

DUAN Guangying , PENG Fang , SONG Zehe , FAN Zhiyong . Biological Function of Rosemary Extract and Its Application in Animal Production[J]. Chinese Journal of Animal Nutrition, 2020 , 32(2) : 516 -522 . DOI: 10.3969/j.issn.1006-267x.2020.02.005

References

[1] 许艺凡,刘普,刘佩佩,等.HPLC-DAD法测定迷迭香茎和叶中11种抗氧化活性成分[J].中草药,2018,49(9):2153-2157.
[2] DE OLIVEIRA J R,CAMARGO S E A,DE OLIVEIRA L D.Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent[J].Journal of Biomedical Science,2019,26:5.
[3] BEL-RHLID R,CRESPY V,PAGÉ-ZOERKLER N,et al.Hydrolysis of rosmarinic acid from rosemary extract with esterases and Lactobacillus johnsonii in vitro and in a gastrointestinal model[J].Journal of Agricultural & Food Chemistry,2009,57(17):7700-7705.  
[4] LAFAY S,GIL-IZQUIERDO A.Bioavailability of phenolic acids[J].Phytochemistry Reviews,2008,7(2):301-311.  
[5] 刘胜男,余敏敏,潘菁菁,等.模拟胃肠道消化过程中迷迭香提取物总酚及抗氧化活性变化规律研究[J/OL].食品工业科技:1-9[2019-09-12].http://kns.cnki.net/kcms/detail/11.1759.TS.20190426.1422.026.html.
[6] 刘国艳,张洁,徐鑫,等.体外消化对芹菜黄酮混合物和单体的含量及抗氧化应激能力的影响[J].食品科学,2018,39(18):8-14.
[7] SVEDSTRÖM U,VUORELA H,KOSTIAINEN R,et al.Fractionation of polyphenols in hawthorn into polymeric procyanidins,phenolic acids and flavonoids prior to high-performance liquid chromatographic analysis[J].Journal of Chromatography A,2006,1112(1/2):103-111.
[8] PÉREZ-SÁNCHEZ A,PÉREZ-SÁNCHEZ I,BARRAJÓN-CATALÁN E,et al.Evaluation of the intestinal permeability of rosemary (Rosmarinus officinalis L.) extract polyphenols and terpenoids in Caco-2 cell monolayers[J].PLoS One,2017,12(2):e172063.
[9] FERNÁNDEZ-OCHOA Á,BORRÁS-LINARES I,PÉREZ-SÁNCHEZ A,et al.Phenolic compounds in rosemary as potential source of bioactive compounds against colorectal cancer:in situ absorption and metabolism study[J].Journal of Functional Foods,2017,33:202-210.
[10] 周慧灵,梁婉娴,徐道立,等.迷迭香活性提取物的药理作用研究进展[J].环球中医药,2015,8(12):1542-1545.
[11] FADEL O,EL KIRAT K,MORANDAT S.The natural antioxidant rosmarinic acid spontaneously penetrates membranes to inhibit lipid peroxidation in situ[J].Biochimica et Biophysica Acta:Biomembranes,2011,1808(12):2973-2980.  
[12] 郑秋闿,范晶晶.迷迭香提取物的主要成分及其抗氧化作用研究[J].实验技术与管理,2017,34(8):43-46.
[13] 刘凤霞,王莹,薛刚,等.迷迭香脂溶性提取物在栀子油中的抗氧化性研究[J].中国油脂,2019,44(1):101-104.
[14] GAO Y,ZHUANG H,YEH H Y,et al.Effect of rosemary extract on microbial growth,pH,color,and lipid oxidation in cold plasma-processed ground chicken patties[J].Innovative Food Science & Emerging Technologies,2019,57:102168.
[15] 鲁青,黄继超,朱宗帅,等.响应面法优化天然抗氧化剂抑制调理鸡排褪色和脂质氧化工艺[J].食品科学,2019,40(6):296-303.
[16] 贾娜,郭倩,宋立,等.迷迭香提取对鸡肉糜冷藏过程中品质特性的影响[J].食品与发酵科技,2014,50(1):60-63,91.
[17] 张志毕,杨晖,张媛,等.迷迭香提取物对小鼠急性酒精肝模型保护作用研究[J].天然产物研究与开发,2017,29(2):229-234.
[18] DE OLIVEIRA J R,DE JESUS D,FIGUEIRA L W,et al.Biological activities of Rosmarinus officinalis L. (rosemary) extract as analyzed in microorganisms and cells[J].Experimental Biology and Medicine,2017,242(6):625-634.  
[19] MORENO S,SCHEYER T,ROMANO C S,et al.Antioxidant and antimicrobial activities of rosemary extracts linked to their polyphenol composition[J].Free Radical Research,2006,40(2):223-231.  
[20] SACCO C,BELLUMORI M,SANTOMAURO F,et al.An in vitro evaluation of the antibacterial activity of the non-volatile phenolic fraction from rosemary leaves[J].Natural Product Research,2014,29(16):1537-1544.
[21] EKAMBARAM S P,PERUMAL S S,BALAKRISHNAN A,et al.Antibacterial synergy between rosmarinic acid and antibiotics against methicillin-resistant Staphylococcus aureus[J].Journal of Intercultural Ethnopharmacology,2016,5(4):358-363.  
[22] JEONG S,PARK H,HONG S,et al.Lipophilic modification enhances anti-colitic properties of rosmarinic acid by potentiating its HIF-prolyl hydroxylases inhibitory activity[J].European Journal of Pharmacology,2015,747:114-122.
[23] GONZÁLEZ-VALLINAS M,REGLERO G,DE MOLINA A R.Rosemary (Rosmarinus officinalis L.) extract as a potential complementary agent in anticancer therapy[J].Nutrition and Cancer,2015,67(8):1223-1231.  
[24] GONZÁLEZ-VALLINAS M,MOLINA S,VICENTE G,et al.Expression of microRNA-15b and the glycosyltransferase GCNT3 correlates with antitumor efficacy of Rosemary diterpenes in colon and pancreatic cancer[J].PLoS One,2014,9(6):e98556.
[25] 曹树稳,余燕影,温辉梁,等.迷迭香提取物的抗乳腺癌活性研究[J].营养学报,2001,23(3):225-229.
[26] XU Y C,JIANG Z J,JI G,et al.Inhibition of bone metastasis from breast carcinoma by rosmarinic acid[J].Planta Medica,2010,76(10):956-962.  
[27] 李婉婷,韦立群,李清,等.迷迭香酸类似物-11通过EGFR-JNK通路抑制人胃癌MGC-803细胞增殖和迁移[J].中国药理学通报,2019,35(4):504-509.
[28] ISHIDA Y I,YAMASAKI M,YUKIZAKI C,et al.Carnosol,rosemary ingredient,induces apoptosis in adult T-cell leukemia/lymphoma cells via glutathione depletion:proteomic approach using fluorescent two-dimensional differential gel electrophoresis[J].Human Cell,2014,27(2):68-77.  
[29] 姚杨,李蓉,苏杰,等.迷迭香酸对口腔溃疡大鼠炎症因子和免疫功能的影响[J].医学研究生学报,2018,31(1):29-32.
[30] SELMI S,RTIBI K,GRAMI D,et al.Rosemary (Rosmarinus officinalis) essential oil components exhibit anti-hyperglycemic,anti-hyperlipidemic and antioxidant effects in experimental diabetes[J].Pathophysiology,2017,24(4):297-303.  
[31] ZHAO Y T,SEDIGHI R,WANG P,et al.Carnosic Acid as a major bioactive component in rosemary extract ameliorates high-fat-diet-induced obesity and metabolic syndrome in mice[J].Journal of Agricultural and Food Chemistry,2015,63(19):4843-4852.  
[32] RAŠKOVIC A,MILANOVIC I,PAVLOVIC N,et al.Antioxidant activity of rosemary (Rosmarinus officinalis L.) essential oil and its hepatoprotective potential[J].BMC Complementary and Alternative Medicinevolume,2014,14:225.
[33] VAQUERO M R,YÁÑEZ-GASCÓN M J,VILLALBA R G,et al.Inhibition of gastric lipase as a mechanism for body weight and plasma lipids reduction in zucker rats fed a rosemary extract rich in carnosic acid[J].PLoS One,2012,7(6):e39773.
[34] VON SCHONFELD C,HUBER R,TRITTLER R,et al.Rosemary has immunosuppressant activity mediated through the STAT3 pathway[J].Complementary Therapies in Medicine,2018,40:165-170.
[35] MATHLOUTHI N,BOUZAIENNE T,OUESLATI I,et al.Use of rosemary,oregano,and a commercial blend of essential oils in broiler chickens:in vitro antimicrobial activities and effects on growth performance[J].Journal of Animal Science,2011,90(3):813-823.
[36] 刘亚楠,李爱华,谢恺舟,等.迷迭香提取物对京海黄鸡生长性能、免疫器官指数和血清抗氧化性的影响[J].中国兽医学报,2016,36(7):1218-1223,1272.
[37] 李爱华.迷迭香提取物对京海黄鸡肉用性能、肉品质及部分盲肠微生物的影响[D].硕士学位论文.扬州:扬州大学,2014:154-156.
[38] 吕玲.日粮添加迷迭香及其精油可改善鸡肉品质[J].中国家禽,2011,33(18):72.
[39] 王晓慧,辛世杰,邹文斌,等.日粮中添加迷迭香及维生素E、维生素C和大豆油的组合对高温期蛋鸡不同组织HSP70LYZ基因表达量的影响[J].中国兽医学报,2019,39(4):767-773.
[40] 杨建生,林雨鑫,安婷婷,等.迷迭香草粉对高温蛋鸡产蛋性能、蛋品质和血清指标的影响[J].中国饲料,2016(19):9-11,25.
[41] DE OLIVEIRA M J,DE SOUZA K A,VITAL A C P,et al.Clove and rosemary essential oils and encapsuled active principles (eugenol,thymol and vanillin blend) on meat quality of feedlot-finished heifers[J].Meat Science,2017,130:50-57.
[42] YAGOUBI Y,HAJJI H,SMETI S,et al.Growth performance,carcass and noncarcass traits and meat quality of Barbarine lambs fed rosemary distillation residues[J].Animal,2018,12(11):1-8.
[43] LIOTTA L,CHIOFALO V,D'ALESSANDRO E,et al.Supplementation of Rosemary extract in the diet of Nero Siciliano pigs:evaluation of the antioxidant properties on meat quality[J].Animal,2015,9(6):1065-1072.  
[44] ZORAL M A,ISHIKAWA Y,OHSHIMA T,et al.Toxicological effects and pharmacokinetics of rosemary (Rosmarinus officinalis) extract in common carp (Cyprinus carpio)[J].Aquaculture,2018,495:955-960.
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