Effects of Different Supplemental Levels of Tributyrin on Growth Performance, Serum Biochemical Indices, Intestinal Morphology and Nutrient Digestibility of Weaned Piglets

ZHU Rongsheng; XU Wei; WANG Huaizhong; SUN Shouli; LIU Xinhua; LIU Junzhen; HU Hongmei

doi:10.3969/j.issn.1006-267x.2020.02.022

2020 , Vol. 32 >Issue 2: 664 - 673

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.02.022

SWINE NUTRITION AND FEED

Effects of Different Supplemental Levels of Tributyrin on Growth Performance, Serum Biochemical Indices, Intestinal Morphology and Nutrient Digestibility of Weaned Piglets

ZHU Rongsheng ,
XU Wei ,
WANG Huaizhong ,
SUN Shouli ,
LIU Xinhua ,
LIU Junzhen ,
HU Hongmei

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1. Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan 250100, China;
2. Key Laboratory of Disease Control and Animal Breeding of Shandong Province, Jinan 250100, China;
3. Shandong Animal Health Technology Center, Jinan 250022, China

Received date: 2019-07-31

Online published: 2020-02-21

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Abstract

This experiment was to evaluate the effects of different supplemental levels of tributyrin on the growth performance, serum biochemical indices, intestinal morphology and nutrient digestibility of weaned piglets. Two hundred "Duroc×Landrace×Large White" weaned piglets at the age of 21 days with 7.66 kg were selected and randomly divided into 5 groups with 5 replicates in each group and 8 pigs in each replicate. Pigs in the control group were fed the basal diet supplemented with 40 mg/kg bacitracin zinc, and those in the experimental groups Ⅰ, Ⅱ, Ⅲ and Ⅳ were fed the basal diets supplemented with 1 000, 1 500, 2 000 and 2 500 mg/kg tributyrin, respectively. The trial lasted for 42 days. The results showed that, compared with the control group, dietary 2 000 and 2 500 mg/kg tributyrin significantly increased the average daily gain (P<0.05), significantly decreased the feed to gain ratio (P<0.05), and significantly increased the serum content of immunoglobulin M (P<0.05) of weaned piglets. Compared with the control group, dietary 1 500, 2 000 and 2 500 mg/kg tributyrin significantly increased the contents of serum glucose and total protein (P<0.05), significantly increased the villus height and the villus height to crypt depth ratio in jejunum and ileum (P<0.05), significantly increased the apparent digestibility of crude protein, crude fat, calcium and phosphorus (P<0.05), and significantly decreased the globulin content and the diamine oxidase activity in serum (P<0.05) of weaned piglets. Compared with the control group, dietary 1 000 mg/kg tributyrate significantly increased the serum total protein content (P<0.05), significantly decreased the serum diamine oxidase activity (P<0.05), and significantly increased the apparent digestibility of crude protein and crude fat (P<0.05) of weaned piglets. It is concluded that dietary 1 000 to 1 500 mg/kg tributyrin can be a substitute for the antibiotic drug additives, and dietary 2 000 to 2 500 mg/kg tributyrin can not only replace the antibiotic drug additives, but also significantly improve the growth performance, promote intestinal morphology, enhance immunity and increase nutrient digestibility of weaned piglets.

Key words： tributyrin; weaned piglets; growth performance; serum biochemical indices; intestinal morphology; nutrient digestibility

Cite this article

ZHU Rongsheng , XU Wei , WANG Huaizhong , SUN Shouli , LIU Xinhua , LIU Junzhen , HU Hongmei . Effects of Different Supplemental Levels of Tributyrin on Growth Performance, Serum Biochemical Indices, Intestinal Morphology and Nutrient Digestibility of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2020 , 32(2) : 664 -673 . DOI: 10.3969/j.issn.1006-267x.2020.02.022

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