Effects of Diets Fermented with Bacteria and Enzyme on Growth Performance, Nutrient Digestibility, Serum Biochemical Indices and Intestinal Barrier Function of Piglets

FENG Jiangxin; CHEN Daiwen; YU Bing; HE Jun; YU Jie; MAO Xiangbing; HUANG Zhiqing; LUO Yuheng; LUO Junqiu; ZHENG Ping

doi:10.3969/j.issn.1006-267x.2020.03.016

2020 , Vol. 32 >Issue 3: 1099 - 1108

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.03.016

Effects of Diets Fermented with Bacteria and Enzyme on Growth Performance, Nutrient Digestibility, Serum Biochemical Indices and Intestinal Barrier Function of Piglets

FENG Jiangxin ,
CHEN Daiwen ,
YU Bing ,
HE Jun ,
YU Jie ,
MAO Xiangbing ,
HUANG Zhiqing ,
LUO Yuheng ,
LUO Junqiu ,
ZHENG Ping

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Key Laboratory for Animal Disease-Resistance Nutrition of Ministry of Education, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China

Received date: 2019-09-10

Online published: 2020-03-13

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Abstract

The purpose of this experiment was to investigate the effects of diets fermented with bacterial and enzymes on growth performance, nutrient digestibility, serum biochemical indices and intestinal barrier function of piglets. A total of 96 Duroc×Landrace×Yorkshire piglets of 42-day-old with body weight of (8.99±0.75) kg were randomly allocated into 4 groups with 8 replicates per group and 3 piglets per replicate. They were assigned to the control group (CON group, basal diet), antibiotic group (AB group, basal diet+75 mg/kg chlortetracycline), 12 h fermentation group (12 h FER group, 12 h fermented diet) and 24 h fermentation group (24 h FER group, 24 h fermented diet). The trial period was 21 days. The results showed as follows:1) compared with the CON group, the average daily gain (ADG) of piglets in both 12 h FER group and 24 h FER group were significantly increased (P<0.05), while the feed to gain ratio (F/G) and diarrhea rate were significantly reduced (P<0.05). Compared with the AB group, the ADG of piglets in the 24 h FER group was significantly increased (P<0.05), and there was no significant difference in diarrhea rate between two fermented groups (P>0.05) 2) Compared with the CON group and AB group, the digestibility of dry matter, crude protein, ether extract, ash, total energy and total phosphorus in two fermented groups was significantly increased (P<0.05), and there was no significant difference between the two fermented groups (P>0.05). 3) Compared with the CON group and AB group, the crypt depth in duodenum of piglets in 12 h FER group was significantly decreased (P<0.05), the villus height to crypt depth ratio (V/C) in duodenum, the number of goblet cells in jejunum mucosa and ileal villi height of piglets in 12 h FER group were significantly increased (P<0.05), and the occludin (OCLN) mRNA relative expression level in ileum of piglets was significantly increased (P<0.05); the duodenal V/C as well as ileal villi height of piglets in 24 h FER group were significantly increased (P<0.05), and the mRNA expression levels of claudin-1 (CLDN-1) and zonula occludens-1 (ZO-1) in jejunum as well as OCLN mRNA expression level in ileum of piglets in 24 h FER group were significantly increased (P<0.05). This experiment shows that diet fermented with bacteria and enzymes can improve nutrient digestibility and intestinal health, reduce diarrhea rate, thereby resulting in the improvement of growth performance of piglets, and the effects of the fermentation is equivalent or superior to chlortetracycline supplementation.

Key words： fermentation; piglets; growth performance; intestinal barrier

Cite this article

FENG Jiangxin , CHEN Daiwen , YU Bing , HE Jun , YU Jie , MAO Xiangbing , HUANG Zhiqing , LUO Yuheng , LUO Junqiu , ZHENG Ping . Effects of Diets Fermented with Bacteria and Enzyme on Growth Performance, Nutrient Digestibility, Serum Biochemical Indices and Intestinal Barrier Function of Piglets[J]. Chinese Journal of Animal Nutrition, 2020 , 32(3) : 1099 -1108 . DOI: 10.3969/j.issn.1006-267x.2020.03.016

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