Effects of Feeding Artificial Milk on Growth Performance, Intestinal Antioxidant Capacity and Barrier Function of Piglets Weaning at 14 Days of Age

XIN Huailu; JIANG Junjie; CHEN Daiwen; HE Jian; LI Yuanfeng; YU Bing; HE Jun; HUANG Zhiqing; MAO Xiangbing; YU Jie; LUO Yuheng; LUO Junqiu; ZHENG Ping

doi:10.3969/j.issn.1006-267x.2020.03.017

2020 , Vol. 32 >Issue 3: 1109 - 1117

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.03.017

Effects of Feeding Artificial Milk on Growth Performance, Intestinal Antioxidant Capacity and Barrier Function of Piglets Weaning at 14 Days of Age

XIN Huailu ,
JIANG Junjie ,
CHEN Daiwen ,
HE Jian ,
LI Yuanfeng ,
YU Bing ,
HE Jun ,
HUANG Zhiqing ,
MAO Xiangbing ,
YU Jie ,
LUO Yuheng ,
LUO Junqiu ,
ZHENG Ping

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1. Key Laboratory for Animal Disease-Resistance Nutrition of Ministry of Education, Institute of Animal Nutrition, Sichuan Agricultural University, Ya'an 625014, China;
2. College of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China;
3. Feng Guang De Laboratory of Tols Tie Qi Li Shi Group, Mianyang 610000, China

Received date: 2019-08-21

Online published: 2020-03-13

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Abstract

This experiment was conducted to investigate the effects of feeding artificial milk on growth performance, intestinal antioxidant capacity and barrier function of piglets weaning at 14 days of age. One hundred and twelve "Landrace×Yorkshire" crossbred piglets at 14 days of age with average body weight of (4.79±0.56) kg from 14 litters were randomly assigned to weaning at 21 days of age group and weaning at 14 days of age group, with 7 replicates per group and 8 piglets per replicate. Piglets in weaning at 21 days of age group were fed breast milk by original sows from 14 to 21 days of age, and the others in weaning at 14 days of age group were fed artificial milk after weaning until 21 days of age. Piglets in two groups were fed same creep feed from 22 days of age, and the experiment lasted for 14 days. The results showed as follows:compared with weaning at 21 days of age, 1) weaning at 14 days of age extremely significantly decreased average daily gain (ADG) of piglets from 15 to 21 days of age (P<0.01), significantly increased average daily feed intake (ADFI) from 22 to 28 days of age (P<0.05), and significantly decreased body weight at 21 days of age and diarrhea rate (P<0.05). 2) Weaning at 14 days of age extremely significantly decreased jejunal crypt depth of piglets (P<0.01), and extremely significantly increased villus height to crypt depth ratio (P<0.01). 3) Weaning at 14 days of age extremely significantly increased mRNA relative expression level of ileal NACHT, LRR and PYD domains-containing protein 3 (NLRP3) of piglets (P<0.01), and significantly decreased jejunal mucosa catalase (CAT) activity (P<0.05). In summary, compared with weaning at 21 days of age, weaning at 14 days of age and feeding artificial milk decrease body weight at 28 days of age, jejunal antioxidant capacity and barrier function of piglets, but improve intestinal morphology and reduce diarrhea rate of piglets at 28 days of age.

Key words： artificial milk; weaning day; piglets; growth performance; intestinal health

Cite this article

XIN Huailu , JIANG Junjie , CHEN Daiwen , HE Jian , LI Yuanfeng , YU Bing , HE Jun , HUANG Zhiqing , MAO Xiangbing , YU Jie , LUO Yuheng , LUO Junqiu , ZHENG Ping . Effects of Feeding Artificial Milk on Growth Performance, Intestinal Antioxidant Capacity and Barrier Function of Piglets Weaning at 14 Days of Age[J]. Chinese Journal of Animal Nutrition, 2020 , 32(3) : 1109 -1117 . DOI: 10.3969/j.issn.1006-267x.2020.03.017

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