Effects of Zearalenone and Estradiol on Growth Performance, Nutrient Utilization and Ovary Morphology of Weaned Piglets

LIAO Wenshuang; ZHOU Min; XU Chang; YANG Weiren; YANG Zaibin; HUANG Libo; LIU Faxiao; LIU Mei; JIANG Shuzhen

doi:10.3969/j.issn.1006-267x.2020.03.019

Chinese Journal of Animal Nutrition >

2020 , Vol. 32 >Issue 3: 1127 - 1135

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.03.019

Effects of Zearalenone and Estradiol on Growth Performance, Nutrient Utilization and Ovary Morphology of Weaned Piglets

LIAO Wenshuang ,
ZHOU Min ,
XU Chang ,
YANG Weiren ,
YANG Zaibin ,
HUANG Libo ,
LIU Faxiao ,
LIU Mei ,
JIANG Shuzhen

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Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Technology, Shandong Agricultural University, Tai'an 271018, China

Received date: 2019-08-31

Online published: 2020-03-13

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Abstract

The objective of this study was to evaluate the effects of zearalenone (ZEA) and estradiol (E2) on the growth performance, nutrient utilization and ovary morphology of weaned piglets. A total of thirty healthy weaned gilts (Duroc×Landrace×Large White) aged of 28 to 32 days with an average weight of (13.57±0.41) kg were randomly allocated to three groups with 10 pigs in each group. Pigs in the control group were fed a basal diet, those in the ZEA group were fed the basal diet supplemented with 1.0 mg/kg ZEA, and those in the E2 group were treated with 0.75 mL (1.5 mg E2 per pig) estradiol benzoate every 3-day interval by intramuscular injection. The test lasted for 35 days after a 7-day adaptation. The results show as follows:1) compared with the control group, there were no significant effects on growth performance of weaned gilts in ZEA and E2 groups (P>0.05). 2) Compared with the control group, higher protein apparent metabolic rate (protein biological value and net protein utilization), activities of serum alkaline phosphatase (ALP) and lactic dehydrogenase (LDH) and ovary index of weaned gilts in the ZEA and E2 groups were observed (P<0.05), and ZEA and E2 stimulated follicle develop in the ovarian cortex and atresia follicles were observed. 3) Compare with the ZEA group, the ether extract apparent digestibility, protein apparent metabolic rate and serum LDH activity of weaned gilts in the E2 group was significantly higher (P<0.05), however, the ovary index was significantly lower (P<0.05); meanwhile E2 stimulated a large number of atretic primary follicles in the ovarian cortex. In conclusion, both ZEA and E2 can improve the protein utilization efficiency, disturb serum enzyme activity, promote the ovary development, and lead to atretic follicles of weaned gilts.

Key words： zearalenone; estradiol; gilt; growth performance; nutrient utilization; ovary morphology

Cite this article

LIAO Wenshuang , ZHOU Min , XU Chang , YANG Weiren , YANG Zaibin , HUANG Libo , LIU Faxiao , LIU Mei , JIANG Shuzhen . Effects of Zearalenone and Estradiol on Growth Performance, Nutrient Utilization and Ovary Morphology of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2020 , 32(3) : 1127 -1135 . DOI: 10.3969/j.issn.1006-267x.2020.03.019

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