Effect of &alpha;-Glycerol Monolaurate on Growth Performance, Fecal Microorganism and Serum Immune Factor of Weaned Piglets

LAN Junhong; GUO Xiqin; TANG Jianing; ZHANG Lingling; XU Yinglei; YANG Caimei

doi:10.3969/j.issn.1006-267x.2020.03.020

Chinese Journal of Animal Nutrition >

2020 , Vol. 32 >Issue 3: 1136 - 1142

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.03.020

Effect of α-Glycerol Monolaurate on Growth Performance, Fecal Microorganism and Serum Immune Factor of Weaned Piglets

LAN Junhong ,
GUO Xiqin ,
TANG Jianing ,
ZHANG Lingling ,
XU Yinglei ,
YANG Caimei

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1. College of Animal Science and Technology, Zhejiang Agriculture and Forestry University, Lin'an 311300, China;
2. Zhejiang Huijia Biotechnology Co., Ltd., Anji 313300, China

Received date: 2019-09-05

Online published: 2020-03-13

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Abstract

The experiment was conducted to investigate the effects of α-glycerol monolaurate (α-GML) on growth performance, fecal microorganism and serum immune factor of weaned piglets. A total of 270 piglets weaned at 25 days of age were randomly divided into 3 groups with 6 replicates per group and 15 piglets per replicate according to the same gender and similar weight[(6.74±0.86) kg]. Piglets in the control group were fed a basal diet, and the others in the experimental groups were fed the basal diets supplemented with 500 and 1 000 mg/kg α-GML, respectively. The experiment lasted for 21 days. The results showed as follows:1) compared with the control group, dietary 1 000 mg/kg α-GML increased the daily weight gain of weaned piglets and reduced the feed to gain ratio significantly (P<0.05). 2) Compared with the control group, dietary 1 000 mg/kg α-GML significant reduced the number of Escherichia coli and Salmonella in piglet feces after weaning for 14 and 21 days (P<0.05), and significantly increased the Lactobacillus number in piglet feces after weaning for 21 days (P<0.05). 3) Compared with the control group, dietary 1 000 mg/kg α-GML significantly reduced the contents of inflammatory factors such as tumor necrosis factor-α (TNF-α), interleukin (IL-6) and interleukin-1β (IL-1β) in serum of piglets after weaning for 21 days (P<0.05), while had no significant effects on the serum interferon-β (IFN-β) content (P>0.05). These results indicate that α-GML can significantly improve the growth performance of weaned piglets, reduce the number of intestinal pathogenic bacteria, and relieve inflammation.

Key words： α-glycerol monolaurate; weaned piglets; growth performance; fecal bacteria; immune factor

Cite this article

LAN Junhong , GUO Xiqin , TANG Jianing , ZHANG Lingling , XU Yinglei , YANG Caimei . Effect of α-Glycerol Monolaurate on Growth Performance, Fecal Microorganism and Serum Immune Factor of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2020 , 32(3) : 1136 -1142 . DOI: 10.3969/j.issn.1006-267x.2020.03.020

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