Effects of Dietary Manganese on Fat Deposition and Lipid Metabolism of Fat Tissue in 3 to 4-Month-Old Rex Rabbits

CHEN Xiaoyang; YANG Gouyu; LI Fan; ZHANG Bin; LI Chenyang; LI Fuchang

doi:10.3969/j.issn.1006-267x.2020.04.042

Chinese Journal of Animal Nutrition >

2020 , Vol. 32 >Issue 4: 1836 - 1841

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.04.042

Effects of Dietary Manganese on Fat Deposition and Lipid Metabolism of Fat Tissue in 3 to 4-Month-Old Rex Rabbits

CHEN Xiaoyang ,
YANG Gouyu ,
LI Fan ,
ZHANG Bin ,
LI Chenyang ,
LI Fuchang

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1. College of Animal Science and Technology, Shandong Agricultural University, Tai'an 271018, China;
2. Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Tai'an 271018, China

Received date: 2019-10-17

Online published: 2020-04-16

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Abstract

The experiment was conducted to investigate the effects of dietary manganese on lipid metabolism of fat tissue in growing Rex rabbits. Two hundred 3-month-old health Rex rabbits with similar body weight and good health were randomly divided into 5 groups with 40 replicates in each group and 1 rabbit in each replicate. Rabbits in 5 groups were fed a basal diet containing 0 (control), 5, 10, 20 and 40 mg/kg manganese (in the form of manganese sulfate), respectively. The trial lasted for 7 days for adaptation, and 29 days for test. The results showed as follows:1) compared with the control group, the addition of 10 to 20 mg/kg manganese significantly reduced the scapular fat deposition rate (P<0.05), and the addition of 5 to 40 mg/kg manganese significantly reduced the perigastric fat deposition rate (P<0.05). The level of manganese in the diet had no effect on the perirenal fat deposition rate (P>0.05). 2) The levels of manganese added to the diet had no significant effects on the expression levels of carnitine fatty acyltransferase 2 (CPT2), hormone sensitive lipase (HSL) and peroxisome proliferator-activated receptor beta (PPARβ) genes (P>0.05). Compared with the control group, the addition of 20 to 40 mg/kg manganese significantly reduced the expression level of fatty acid synthase (FAS) gene (P<0.05); the addition of 20 to 40 mg/kg manganese significantly reduced the expression of acetyl-CoA carboxylase (ACC) gene (P<0.05); the addition of 10 to 40 mg/kg manganese in the diet significantly increased the expression of carnitine fatty acyltransferase 1 (CPT1) gene (P<0.05); the addition of 10 to 20 mg/kg manganese in the diet significantly increased the expression of peroxisome proliferator-activated receptor alpha (PPARα) gene (P<0.05). From what has been discussed above, addition of manganese affects fat deposition and fat metabolism of Rex rabbits. When the level of manganese addition is 20 mg/kg, it can effectively promote the oxidation and decomposition of fat in fat tissue, inhibit fat synthesis in fat tissue, and reduce the deposition rate of body fat.

Key words： manganese; Rex rabbits; fat; fat metabolism; genetic expression

Cite this article

CHEN Xiaoyang , YANG Gouyu , LI Fan , ZHANG Bin , LI Chenyang , LI Fuchang . Effects of Dietary Manganese on Fat Deposition and Lipid Metabolism of Fat Tissue in 3 to 4-Month-Old Rex Rabbits[J]. Chinese Journal of Animal Nutrition, 2020 , 32(4) : 1836 -1841 . DOI: 10.3969/j.issn.1006-267x.2020.04.042

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