Effects of Sodium Butyrate on Gastrointestinal Tract Development of Weaned Lambs

ZUO Lijun; CHEN Xiang; WANG Kexin; JIANG Ning; ZHANG Aizhong

doi:10.3969/j.issn.1006-267x.2020.04.052

Chinese Journal of Animal Nutrition >

2020 , Vol. 32 >Issue 4: 1916 - 1926

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.04.052

Effects of Sodium Butyrate on Gastrointestinal Tract Development of Weaned Lambs

ZUO Lijun ,
CHEN Xiang ,
WANG Kexin ,
JIANG Ning ,
ZHANG Aizhong

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Heilongjiang Key Laboratory of High Efficiency Utilization of Feed Resources and Nutrition Manipulation in Cold Region, College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing 163319, China

Received date: 2019-10-27

Online published: 2020-04-16

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Abstract

This experiment was conducted to study the effects of sodium butyrate on gastrointestinal tract development of weaned lambs. Twenty-four 42-day-old weaned lambs were randomly divided into 4 groups with 6 replicates in each group and 1 lamb in each replicate. Lambs in blank control group were fed a basal diet, lambs in antibiotic group were fed the basal diet supplemented with 250 mg/kg of flavomycin, and lambs in sodium butyrate group A and sodium butyrate group B were fed the basal diet supplemented 2 and 3 g/kg coated sodium butyrate, respectively. On days 14 and 28 of the trial, three lambs were selected from each group for slaughter sampling. The results showed that no significant differences in rumen relative weight and relative volume and each gastrointestinal tract morphology indices of weaned lambs among groups on day 14 of the trial (P>0.05). On day 28 of the trial, compared with the blank control group, the muscular layer thickness of rumen dorsal location and the muscular layer thickness and papillae height of rumen abdominal location in sodium butyrate group B were significantly increased (P<0.05), as well as the villus height of duodenum, jejunum and ileum, the villi surface area of jejunum and the villus height/crypt depth of jejunum and ileum (P<0.05). It can be seen that adding 3 g/kg of coated sodium butyrate to the diet for 28 days can promote the growth of rumen papillae and muscular layer, promote the growth of intestinal villi, and increase the intestinal villi height and villus height/crypt depth, which is beneficial to the development of gastrointestinal tract of weaned lambs.

Key words： weaned lambs; sodium butyrate; rumen; small intestine; development

Cite this article

ZUO Lijun , CHEN Xiang , WANG Kexin , JIANG Ning , ZHANG Aizhong . Effects of Sodium Butyrate on Gastrointestinal Tract Development of Weaned Lambs[J]. Chinese Journal of Animal Nutrition, 2020 , 32(4) : 1916 -1926 . DOI: 10.3969/j.issn.1006-267x.2020.04.052

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